Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Joanne M, Murabito"'
Autor:
Gareth Hawkes, Robin N. Beaumont, Zilin Li, Ravi Mandla, Xihao Li, Christine M. Albert, Donna K. Arnett, Allison E. Ashley-Koch, Aneel A. Ashrani, Kathleen C. Barnes, Eric Boerwinkle, Jennifer A. Brody, April P. Carson, Nathalie Chami, Yii-Der Ida Chen, Mina K. Chung, Joanne E. Curran, Dawood Darbar, Patrick T. Ellinor, Myrian Fornage, Victor R. Gordeuk, Xiuqing Guo, Jiang He, Chii-Min Hwu, Rita R. Kalyani, Robert Kaplan, Sharon L. R. Kardia, Charles Kooperberg, Ruth J. F. Loos, Steven A. Lubitz, Ryan L. Minster, Take Naseri, Satupa’itea Viali, Braxton D. Mitchell, Joanne M. Murabito, Nicholette D. Palmer, Bruce M. Psaty, Susan Redline, M. Benjamin Shoemaker, Edwin K. Silverman, Marilyn J. Telen, Scott T. Weiss, Lisa R. Yanek, Hufeng Zhou, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ching-Ti Liu, Kari E. North, Anne E. Justice, Jonathan M. Locke, Nick Owens, Anna Murray, Kashyap Patel, Timothy M. Frayling, Caroline F. Wright, Andrew R. Wood, Xihong Lin, Alisa Manning, Michael N. Weedon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The role of rare non-coding variation in complex human phenotypes is still largely unknown. To elucidate the impact of rare variants in regulatory elements, we performed a whole-genome sequencing association analysis for height using 333,100
Externí odkaz:
https://doaj.org/article/b2e3a91ecb614324b7f2fdd7370d5155
Autor:
Ahmed A. Y. Ragab, Margaret F. Doyle, Jiachen Chen, Yuan Fang, Kathryn L. Lunetta, Joanne M. Murabito
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Global life expectancy is rising, with the 60 + age group projected to hit 2 billion by 2050. Aging impacts the immune system. A notable marker of immune system aging is the presence of Aging-Related Immune Cell Phenotypes (ARIPs)
Externí odkaz:
https://doaj.org/article/c41cb3cf9955436687290af42e544dee
Autor:
Yuankai Zhang, Xuzhi Wang, Chathurangi H Pathiravasan, Nicole L Spartano, Honghuang Lin, Belinda Borrelli, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Ravi V Shah, Gregory D Lewis, Chunyu Liu, Joanne M Murabito, Matthew Nayor
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e56676 (2024)
BackgroundResting heart rate (HR) and routine physical activity are associated with cardiorespiratory fitness levels. Commercial smartwatches permit remote HR monitoring and step count recording in real-world settings over long periods of time, but t
Externí odkaz:
https://doaj.org/article/e9e5182e9c70429c97c986c03547143c
Autor:
Madeleine Carbonneau, Yi Li, Brenton Prescott, Chunyu Liu, Tianxiao Huan, Roby Joehanes, Joanne M. Murabito, Nancy L. Heard‐Costa, Vanessa Xanthakis, Daniel Levy, Jiantao Ma
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 11 (2024)
Background Life's Essential 8 (LE8) is an enhanced metric for cardiovascular health. The interrelations among LE8, biomarkers of aging, and disease risks are unclear. Methods and Results LE8 score was calculated for 5682 Framingham Heart Study partic
Externí odkaz:
https://doaj.org/article/1b64265b7fdb4c7e8fcd7a1aec80b27c
Autor:
Joanne M Murabito, Jamie M Faro, Yuankai Zhang, Angelo DeMalia, Alexander Hamel, Nakesha Agyapong, Hongshan Liu, Eric Schramm, David D McManus, Belinda Borrelli
Publikováno v:
JMIR Human Factors, Vol 11, p e56653 (2024)
BackgroundStudies evaluating the usability of mobile-phone assessments in older adults are limited. ObjectiveThis study aims to identify design-based barriers and facilitators to mobile app survey completion among 2 samples of older adults; those in
Externí odkaz:
https://doaj.org/article/611233275f6c4203bdcce75ef4377985
Autor:
Xuzhi Wang, Yuankai Zhang, Chathurangi H Pathiravasan, Nene C Ukonu, Jian Rong, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Naomi M Hamburg, Joanne M Murabito, Chunyu Liu, Gary F Mitchell
Publikováno v:
JMIR Cardio, Vol 8, p e54801 (2024)
BackgroundShort-term blood pressure variability (BPV) is associated with arterial stiffness in patients with hypertension. Few studies have examined associations between arterial stiffness and digital home BPV over a mid- to long-term time span, irre
Externí odkaz:
https://doaj.org/article/09999f0f3f80430f9aef7c4ab1b43faa
Autor:
Yun Soo Hong, Stephanie L. Battle, Wen Shi, Daniela Puiu, Vamsee Pillalamarri, Jiaqi Xie, Nathan Pankratz, Nicole J. Lake, Monkol Lek, Jerome I. Rotter, Stephen S. Rich, Charles Kooperberg, Alex P. Reiner, Paul L. Auer, Nancy Heard-Costa, Chunyu Liu, Meng Lai, Joanne M. Murabito, Daniel Levy, Megan L. Grove, Alvaro Alonso, Richard Gibbs, Shannon Dugan-Perez, Lukasz P. Gondek, Eliseo Guallar, Dan E. Arking
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mitochondria carry their own circular genome and disruption of the mitochondrial genome is associated with various aging-related diseases. Unlike the nuclear genome, mitochondrial DNA (mtDNA) can be present at 1000 s to 10,000 s copies in so
Externí odkaz:
https://doaj.org/article/8424ec81fd124e7695c09c8c5db1a8bc
Autor:
Mariana F. Ramirez, Michael Honigberg, Dongyu Wang, Juhi K. Parekh, Kamila Bielawski, Paul Courchesne, Martin D. Larson, Daniel Levy, Joanne M. Murabito, Jennifer E. Ho, Emily S. Lau
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 16 (2023)
Background Premature and early menopause are independently associated with greater risk of cardiovascular disease (CVD). However, mechanisms linking age of menopause with CVD remain poorly characterized. Methods and Results We measured 71 circulating
Externí odkaz:
https://doaj.org/article/811f832177584edd8aa262d80a8022bf
Autor:
Chathurangi H. Pathiravasan, Yuankai Zhang, Xuzhi Wang, Ludovic Trinquart, Emelia J. Benjamin, Belinda Borrelli, David D. McManus, Vik Kheterpal, Honghuang Lin, Nicole L. Spartano, Eric Schramm, Chunyu Liu, Joanne M. Murabito
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-11 (2022)
Abstract Long-term use of digital devices is critical for successful clinical or research use, but digital health studies are challenged by a rapid drop-off in participation. A nested e-cohort (eFHS) is embedded in the Framingham Heart Study and uses
Externí odkaz:
https://doaj.org/article/7e28d9f22a3d48a79663ea723f5f6793
Autor:
M d Mesbah Uddin, Ngoc Quynh H. Nguyen, Bing Yu, Jennifer A. Brody, Akhil Pampana, Tetsushi Nakao, Myriam Fornage, Jan Bressler, Nona Sotoodehnia, Joshua S. Weinstock, Michael C. Honigberg, Daniel Nachun, Romit Bhattacharya, Gabriel K. Griffin, Varuna Chander, Richard A. Gibbs, Jerome I. Rotter, Chunyu Liu, Andrea A. Baccarelli, Daniel I. Chasman, Eric A. Whitsel, Douglas P. Kiel, Joanne M. Murabito, Eric Boerwinkle, Benjamin L. Ebert, Siddhartha Jaiswal, James S. Floyd, Alexander G. Bick, Christie M. Ballantyne, Bruce M. Psaty, Pradeep Natarajan, Karen N. Conneely
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Clonal hematopoiesis, often caused by mutations in DNMT3A and TET2, is associated with blood cancer and coronary artery disease. Here, the authors conduct an epigenome-wide association study, finding that clonal hematopoiesis caused by DNMT3A vs. TET
Externí odkaz:
https://doaj.org/article/c22e81f057bd44ef857ef1b82f628c5a