Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Joanne M, Fraser"'
Publikováno v:
The Journal of Immunology. 180:7305-7317
Regulatory CD4+CD25+Foxp3+ T cells play a critical role in controlling autoimmunity and T cell homeostasis. However, their role in regulation of lymphopenia-induced proliferation (LIP), a potential mechanism for generation of autoaggressive T cells,
Publikováno v:
Journal of Leukocyte Biology. 83:1230-1239
Although regulatory CD4CD25 forkhead box p3 (Foxp3) T cells (Tregs) are generally thought to arise in the thymus as a sepa- rate lineage of CD4 T cells, they can also be in- duced de novo in the periphery. Peripheral devel- opment of Tregs from naive
Publikováno v:
Immunology. 119:126-133
InsHA mice express the haemagglutinin (HA) protein from influenza virus A/PR/8 H1N1 (PR8) as a self antigen on pancreatic islet beta cells. We have utilized these mice to investigate the ability of resting B cells expressing Kd to induce self-toleran
Autor:
Alexander Khoruts, Joanne M. Fraser
Publikováno v:
Immunology Letters
It is well recognized that the composition of the mature T cell population is subject to strict homeostatic control. The TCR repertoire and relative proportions of various T cell subsets are established in the thymus, and continue to be shaped and re
Publikováno v:
Cutis. 72
Duac Topical Gel (clindamycin 1%-benzoyl peroxide 5%) is a uniform, aqueous gel manufactured under the US Food and Drug Administration (FDA) Current Good Manufacturing Practice (cGMP) regulations and controls, which ensure that consistent product is
Publikováno v:
Biochemical pharmacology. 44(9)
2,2,2-Trifluoroethanol (TFE) is a metabolite of anesthetic agents and chlorofluorocarbon alternatives. Its toxicity in rats is a consequence of its metabolism to 2,2,2-trifluoroacetaldehyde (TFAld) and then to trifluoroacetic acid (TFAA). The enzymes
Publikováno v:
Journal of the American Academy of Dermatology. 50:P16
Publikováno v:
Journal of the American Academy of Dermatology. 50:P11
Publikováno v:
Toxicologic Pathology. 15:388-400
The lethal effects of the fluorinated ether anesthetic, fluroxene, in rats are a consequence of its metabolism, which is catalyzed by cytochrome P-450 to the toxic metabolite 2,2,2-trifluoroethanol (TFE). The anesthetic or TFE (0.21 g/kg) caused decr
Publikováno v:
Toxicology and applied pharmacology. 84(1)
2,2,2-Trifluoroethanol (TFE) is the toxic metabolite of the anesthetic agent fluroxene. TFE treatment (0.21 g/kg, ip) of male Wistar rats significantly reduced peripheral white blood cell count, bone marrow nucleated cellularity, and dry weight of th