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Autor:
Sharmista Chatterjee, Minerva Hughes, Martin K. McDermott, Dinesh V. Patwardhan, Tina Zhang, Anastasiya Belyaeva, Celia N. Cruz, Joanne Leadbetter, Nancy Tang, David M. Saylor, Ariel Ash-Shakoor, Conrad W. Merkle, Xiaoli Hu, Reginald K. Avery, Taylor Moot, Sepideh Parvinian
Publikováno v:
AAPS PharmSciTech. 16:811-823
The drug coating process for coated drug-eluting stents (DES) has been identified as a key source of inter- and intra-batch variability in drug elution rates. Quality-by-design (QbD) principles were applied to gain an understanding of the ultrasonic