Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages.

Autor: Ruth Forman, Larisa Logunova, Hannah Smith, Kelly Wemyss, Iris Mair, Louis Boon, Judith E Allen, Werner Muller, Joanne L Pennock, Kathryn J Else

Publikováno v: PLoS Pathogens, Vol 17, Iss 7, p e1009768 (2021)

The intestinal nematode parasite Trichuris muris dwells in the caecum and proximal colon driving an acute resolving intestinal inflammation dominated by the presence of macrophages. Notably, these macrophages are characterised by their expression of

Externí odkaz: https://doaj.org/article/c66c777140c7426f8f87146164ffbd92

Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages

Autor: Werner Müller, Hannah Smith, Louis Boon, Kelly Wemyss, Iris Mair, Judith E. Allen, Larisa Logunova, Ruth Forman, Kathryn J. Else, Joanne L. Pennock

Publikováno v: PLoS Pathogens, Vol 17, Iss 7, p e1009768 (2021)
Forman, R, Logunova, L, Smith, H, Wemyss, K, Mair, I, Boon, L, Allen, J, Muller, W, Pennock, J & Else, K 2021, ' Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELM alpha plus macrophages ', PL o S Pathogens, vol. 17, no. 7, e1009768, pp. e1009768 . https://doi.org/10.1371/journal.ppat.1009768
PLoS Pathogens

The intestinal nematode parasite Trichuris muris dwells in the caecum and proximal colon driving an acute resolving intestinal inflammation dominated by the presence of macrophages. Notably, these macrophages are characterised by their expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4900d6f161587e8f6a8da1c3cc3591a6
https://doaj.org/article/c66c777140c7426f8f87146164ffbd92

Splenic capture and in vivo intracellular biodegradation of biological-grade graphene oxide sheets

Autor: Irene de Lázaro, Cyrill Bussy, Neus Lozano, Bakri M. Assas, Leon Newman, Kostas Kostarelos, Sarah J. Haigh, Yein Nam, Eric Prestat, Dhifaf A. Jasim, Joanne L. Pennock

Publikováno v: ACS Nano
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Newman, L, Jasim, D, Prestat, E, Lozano, N, De Lazaro Del Rey, I, Nam, Y, Assas, M, Pennock, J, Haigh, S, Bussy, C & Kostarelos, K 2020, ' Splenic Capture and In Vivo Intracellular Biodegradation of Biological-grade Graphene Oxide Sheets ', A C S Nano, vol. 14, no. 8, pp. 10168-10186 . https://doi.org/10.1021/acsnano.0c03438

Carbon nanomaterials, including 2D graphene-based materials, have shown promising applicability to drug delivery, tissue engineering, diagnostics, and various other biomedical areas. However, to exploit the benefits of these materials in some of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8254cb3e371513b1d9d7ec0fe0fea311
https://ddd.uab.cat/record/236007

Early induction of C/EBPβ expression as a potential marker of steroid responsive colitis

Autor: Scott Levison, Mushref Bakri Assas, Joanne L. Pennock

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Assas, M, Levison, S & Pennock, J 2019, ' Early induction of C/EBPβ expression as a potential marker of steroid responsive colitis. ', Scientific Reports, vol. 9, no. 1, pp. 13087 . https://doi.org/10.1038/s41598-019-48251-9

The precise mechanism of hydrocortisone immune regulation in the management of colitis is poorly understood. Whilst not without limitations, its ability to suppress pathology and rapidly improve patient clinical outcome is key. We were interested in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba16d9302b4c8795a4703ca91862a57
http://europepmc.org/articles/PMC6739378

Staphylococcus aureus second immunoglobulin-binding protein drives atopic dermatitis via IL-33

Autor: Charis R Saville, Hiroshi Matsuda, Joanne L. Pennock, Kenshiro Matsuda, Arwa Al Kindi, Helen L. Williams, Abdullah M. Alkahtani, Akane Tanaka, Yasmine Alshammari, Catherine A. O'Neill, Hayley M. Bennett, Peter D. Arkwright, Soo Yee Tan

Publikováno v: Al Kindi, A, Williams, H, Matsuda, K, Alkahtani, A, Saville, C, Bennett, H, Alshammari, Y, Tan, S Y, O'Neill, C, Tanaka, A, Matsuda, H, Arkwright, P & Pennock, J 2021, ' Staphylococcus aureus Second Immunoglobulin-Binding Protein drives atopic dermatitis via IL-33 ', Journal of Allergy and Clinical Immunology, vol. 147, no. 4, 0, pp. 1354-1368.e3 . https://doi.org/10.1016/j.jaci.2020.09.023

Background Staphylococcus aureus is the dominant infective trigger of atopic dermatitis (AD). How this bacterium drives type 2 allergic pathology in the absence of infection in patients with AD is unclear. Objective We sought to identify the S aureus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98ba9896de5ebe012a3a112016465ce
https://doi.org/10.1016/j.jaci.2020.09.023