Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Joanne L, Dunster"'
Autor:
Chukiat Tantiwong, Joanne L. Dunster, Rachel Cavill, Michael G. Tomlinson, Christoph Wierling, Johan W. M. Heemskerk, Jonathan M. Gibbins
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Receptor diffusion plays an essential role in cellular signalling via the plasma membrane microenvironment and receptor interactions, but the regulation is not well understood. To aid in understanding of the key determinants of receptor diff
Externí odkaz:
https://doaj.org/article/2abb3eaafda6408294a30fc4910406b0
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
IntroductionAdvancing understanding of key factors that determine the magnitude of the hemostatic response may facilitate the identification of individuals at risk of generating an occlusive thrombus as a result of an atherothrombotic event such as a
Externí odkaz:
https://doaj.org/article/c4d6ed06112a4061a610fe589a40dbd9
Autor:
Delia I. Fernández, Isabella Provenzale, Hilaire Y.F. Cheung, Jan van Groningen, Bibian M.E. Tullemans, Alicia Veninga, Joanne L. Dunster, Saman Honarnejad, Helma van den Hurk, Marijke J.E. Kuijpers, Johan W.M. Heemskerk
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103718- (2022)
Summary: Antiplatelet drugs targeting G-protein-coupled receptors (GPCRs), used for the secondary prevention of arterial thrombosis, coincide with an increased bleeding risk. Targeting ITAM-linked receptors, such as the collagen receptor glycoprotein
Externí odkaz:
https://doaj.org/article/41f61631ed79476488c1835c6a7c8eef
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008413 (2020)
Many common medical conditions (such as cancer, arthritis, chronic obstructive pulmonary disease (COPD), and others) are associated with inflammation, and even more so when combined with the effects of ageing and multimorbidity. While the inflammator
Externí odkaz:
https://doaj.org/article/7418d2b4d19b4200aefbc80a73f1c593
Autor:
Joanne L. Dunster, Martin R. Nelson
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ead9dc36e219c8f33c50b681fdd58fd4
https://doi.org/10.1016/b978-0-12-821618-7.00029-8
https://doi.org/10.1016/b978-0-12-821618-7.00029-8
Publikováno v:
Chaos, Solitons & Fractals. 170:113338
Autor:
Dmitry Yu. Nechipurenko, Vitaly Volpert, Mikhail A. Panteleev, Fazoil Ataullahanov, Joanne L. Dunster, Valeriia N. Kaneva
Publikováno v:
Biophys J
Biophysical Journal
Biophysical Journal, 2021, 120 (2), pp.334-351. ⟨10.1016/j.bpj.2020.10.049⟩
Biophysical Journal
Biophysical Journal, 2021, 120 (2), pp.334-351. ⟨10.1016/j.bpj.2020.10.049⟩
Damage to arterial vessel walls leads to the formation of platelet aggregate, which acts as a physical obstacle for bleeding. An arterial thrombus is heterogeneous; it has a dense inner part (core) and an unstable outer part (shell). The thrombus she
Autor:
Rocel C. Saputil, Joanne L. Dunster, Neline Kriek, Yunchuan Ding, Michelle M.H. Tan, Emma Thorley, Clio Pillay, Asad Charania, Margarita Dominguez-Villar, Wayne A. Mitchell, Amna Malik, Jonathan M. Gibbins, Nichola Cooper
Publikováno v:
Blood. 140:11263-11264
Autor:
Rocel C. Saputil, Joanne L. Dunster, Neline Kriek, Yunchuan Ding, Anuradha Bhide, Alice C J Hart, Michelle MH Tan, Emma Thorley, Ariam Teklemichael, Wayne A. Mitchell, Amna Malik, Jonathan M. Gibbins, Nichola Cooper
Publikováno v:
Blood. 140:2691-2692
Autor:
Jo L. Mitchell, Yasmin M. M. Mohammed, Jonathan M. Gibbins, Kirk A. Taylor, Joanne L. Dunster, Chris I. Jones
Publikováno v:
Journal of visualized experiments : JoVE. (176)
Platelets react rapidly to vascular injury and undergo activation in response to a range of stimuli to limit blood loss. Many platelet function tests measure endpoint responses after a defined time period and not the rate of platelet activation. Howe