Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Joanne K. Tobacman"'
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-4 (2024)
Abstract Proglucagon mRNA expression and GLP-1 secretion by cultured human L-cells (NCI-H716) were inhibited following exposure to λ-carrageenan, a commonly used additive in processed foods. Carrageenan is composed of sulfated or unsulfated galactos
Externí odkaz:
https://doaj.org/article/b79378c588164a67b7a958128d947dca
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Immunostaining in lungs of patients who died with COVID-19 infection showed increased intensity and distribution of chondroitin sulfate and decline in N-acetylgalactostamine-4-sulfatase (Arylsulfatase B; ARSB). To explain these findings, hum
Externí odkaz:
https://doaj.org/article/954e5fe337e246769f3e781862f06b24
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5851 (2024)
The effects of the enzyme N-acetylgalactosamine-4-sulfatase (Arylsulfatase B, ARSB), which removes the 4-sulfate group at the non-reducing end of chondroitin 4-sulfate, on the expression of PD-L1 were determined, and the underlying mechanism of PD-L1
Externí odkaz:
https://doaj.org/article/5a4b990e27ec466587501363d5238b37
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13146 (2022)
The enzyme N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) was originally identified as a lysosomal enzyme which was deficient in Mucopolysaccharidosis VI (MPS VI; Maroteaux-Lamy Syndrome). The newly directed attention to the impact of ARSB
Externí odkaz:
https://doaj.org/article/a727909c4e3842bab628766b1afa7f70
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Exposure to low concentration of the common food additive carrageenan (10 mg/L) for only six days led to glucose intolerance and insulin resistance in the C57BL/6J mouse. Longer exposure produced fasting hyperglycemia but with no increase in weight,
Externí odkaz:
https://doaj.org/article/35807c73e1e84314986c1fa88ba6efbb
Publikováno v:
Journal of Diabetes Research, Vol 2015 (2015)
Aims. Major aims were to determine whether exposure to the commonly used food additive carrageenan could induce fasting hyperglycemia and could increase the effects of a high fat diet on glucose intolerance and dyslipidemia. Methods. C57BL/6J mice we
Externí odkaz:
https://doaj.org/article/48d217052f394159a1708853dbf981ea
Autor:
Sumit Bhattacharyya, Liquan Xue, Suzanne Devkota, Eugene Chang, Stephan Morris, Joanne K. Tobacman
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
The common food additive carrageenan is a known activator of inflammation in mammalian tissues and stimulates both the canonical and noncanonical pathways of NF-κB activation. Exposure to low concentrations of carrageenan (10 μg/mL in the water sup
Externí odkaz:
https://doaj.org/article/470184db464a42f0b3b6a6e391c20bbe
Immunostaining in lungs of patients who died with Covid-19 infection showed increased intensity and distribution of chondroitin sulfate and carbohydrate sulfotransferase (CHST)15 and decline in N-acetylgalactostamine-4-sulfatase (Arylsulfatase B; ARS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a1544655b974f5255d8a0e6c2033f4e
https://doi.org/10.1101/2023.01.24.23284890
https://doi.org/10.1101/2023.01.24.23284890
Publikováno v:
Pathobiology. 89:81-91
Introduction: The potential role of accumulation of chondroitin sulfates (CSs) in the pathobiology of COVID-19 has not been examined. Accumulation may occur by increased synthesis or by decline in activity of the enzyme arylsulfatase B (ARSB; N-acety
Autor:
Amar Dodda, Hui Xie, Allan G. Halline, Krista A. Varady, Joanne K. Tobacman, Sumit Bhattacharyya, Leo Feferman, Stephen B. Hanauer
Publikováno v:
Nutrition and Healthy Aging
BACKGROUND: Carrageenan is a very common food additive in Western diets, but predictably causes inflammation in thousands of cell-based and animal experiments. OBJECTIVE: To assess the impact of carrageenan exposure on the interval to relapse in pati