Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joanne K. Gardner"'
Autor:
Connie Jackaman, Joanne K. Gardner, Federica Tomay, Joshua Spowart, Hannah Crabb, Danielle E. Dye, Simon Fox, Stephen Proksch, Pat Metharom, Satvinder S. Dhaliwal, Delia J. Nelson
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Increasing life expectancy is associated with increased cancer incidence, yet the effect of cancer and anti-cancer treatment on elderly patients and their immune systems is not well understood. Declining T cell function with aging in response to infe
Externí odkaz:
https://doaj.org/article/06c4c63caab64849b58b54f7f6e78f6d
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Aging is associated with an increased incidence of cancer. One contributing factor could be modulation of immune cells responsible for anti-tumor responses, such as dendritic cells (DCs) and T cells. These immunological changes may also impact the ef
Externí odkaz:
https://doaj.org/article/e9d3a43bf2e54649a3adce411203ce8e
Autor:
Lelinh Duong, Hannah G. Radley-Crabb, Joanne K. Gardner, Federica Tomay, Danielle E. Dye, Miranda D. Grounds, Fiona J. Pixley, Delia J. Nelson, Connie Jackaman
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Most cancers emerge in the elderly, including lung cancer and mesothelioma, yet the elderly remain an underrepresented population in pre-clinical cancer studies and clinical trials. The immune system plays a critical role in the effectiveness of many
Externí odkaz:
https://doaj.org/article/a75ea3d3d6244e59b54676d2c6b43b13
Autor:
Joanne K Gardner, Cyril D S Mamotte, Priya Patel, Teong Ling Yeoh, Connie Jackaman, Delia J Nelson
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123563 (2015)
Dendritic cells (DCs) play an important role in the generation of anti-cancer immune responses, however there is evidence that DCs in cancer patients are dysfunctional. Lipid accumulation driven by tumor-derived factors has recently been shown to con
Externí odkaz:
https://doaj.org/article/19accf8c9e384f04aebba9a1b187e300
Publikováno v:
Ageing Research Reviews. 38:40-51
Dendritic cells (DCs) undergo continuous changes throughout life, and there is evidence that elderly DCs have a reduced capacity to stimulate T cells, which may contribute to impaired anti-tumour immune responses in elderly people with cancer. Change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fa9659dbab16e7111fc3c695b3876e
https://doi.org/10.1016/j.arr.2017.07.002
https://doi.org/10.1016/j.arr.2017.07.002
Autor:
Pat Metharom, Simon A. Fox, Stephen Proksch, Danielle E. Dye, Satvinder S. Dhaliwal, Delia J. Nelson, Hannah Crabb, Federica Tomay, Connie Jackaman, Joanne K. Gardner, Joshua Spowart
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Increasing life expectancy is associated with increased cancer incidence, yet the effect of cancer and anti-cancer treatment on elderly patients and their immune systems is not well understood. Declining T cell function with aging in response to infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b225b508181346a7ad8f12ad479ea525
https://doaj.org/article/06c4c63caab64849b58b54f7f6e78f6d
https://doaj.org/article/06c4c63caab64849b58b54f7f6e78f6d
Publikováno v:
Regenerative Medicine and Plastic Surgery ISBN: 9783030199616
Human skin regeneration is highly dependent on the growth factors provided by mesenchymal support cells. Here we review the current understanding of the various cell types both heterotypic and homotypic that are capable of promoting the culture, expa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9845bd5a066bb1ac958c7c94da4aac8
https://doi.org/10.1007/978-3-030-19962-3_7
https://doi.org/10.1007/978-3-030-19962-3_7
Autor:
Connie, Jackaman, Joanne K, Gardner, Federica, Tomay, Joshua, Spowart, Hannah, Crabb, Danielle E, Dye, Simon, Fox, Stephen, Proksch, Pat, Metharom, Satvinder S, Dhaliwal, Delia J, Nelson
Publikováno v:
Oncoimmunology
Increasing life expectancy is associated with increased cancer incidence, yet the effect of cancer and anti-cancer treatment on elderly patients and their immune systems is not well understood. Declining T cell function with aging in response to infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2da78e432dde0ab20b307f810b84c8be
https://pubmed.ncbi.nlm.nih.gov/30906657
https://pubmed.ncbi.nlm.nih.gov/30906657
Autor:
Hannah G. Radley-Crabb, Miranda D. Grounds, Danielle E. Dye, Delia J. Nelson, Federica Tomay, Connie Jackaman, Joanne K. Gardner, Fiona J. Pixley, Lelinh Duong
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics, Vol 9 (2018)
Most cancers emerge in the elderly, including lung cancer and mesothelioma, yet the elderly remain an underrepresented population in pre-clinical cancer studies and clinical trials. The immune system plays a critical role in the effectiveness of many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8b5f54f83d5cd919b16a1fc4c9ea1d
https://pubmed.ncbi.nlm.nih.gov/30459812
https://pubmed.ncbi.nlm.nih.gov/30459812
Autor:
Delia J. Nelson, Anna K. Nowak, John M. Alvarez, Arthur W. Musk, Cyril D. S. Mamotte, Scott M.J. Cornwall, Joanne K. Gardner, Connie Jackaman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0195313 (2018)
PLoS ONE, Vol 13, Iss 4, p e0195313 (2018)
There is evidence that dendritic cells (DCs) undergo age-related changes that modulate their function with their key role being priming antigen-specific effector T cells. This occurs once DCs develop into antigen-presenting cells in response to stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4504f478cc9e91a11b4580939c708902
http://europepmc.org/articles/PMC5898732
http://europepmc.org/articles/PMC5898732