Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joanne Huber"'
Autor:
Kevin M. Byrne, M. Teresa Díez, Joanne Huber, Oscar Salazar, Deborah L. Zink, Olga Genilloud, Sheo B. Singh, Francisca Vicente, Angela Basilio
Publikováno v:
Organic Letters. 8:5449-5452
Inhibition of protein synthesis is one of the validated and highly successful targets for inhibition of bacterial growth; this mechanism is a target of a large number of clinical drugs. Ribosomal protein S4, a primary protein, is a potential target f
Autor:
Francisca Vicente, Angela Basilio, Olga Genilloud, Sheo B. Singh, M. Teresa Díez, Deborah L. Zink, Kevin M. Byrne, Oscar Salazar, Joanne Huber
Publikováno v:
ChemInform. 38
Autor:
Gail G. Hammond, J.V. Heck, Dann L. Parker, Timothy A. Blizzard, Kenneth J. Wildonger, Jon G. Sundelof, Walter J. May, Ronald W. Ratcliffe, Sherman T. Waddell, Robert R. Wilkening, Milton L. Hammond, Joanne Huber, Karen Dorso, Gina M. Santorelli, Joyce Kohler, E. St. Rose, Jerry D. Morgan
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(5)
A series of 1beta-methyl-2-(naphthosultamyl)methyl-carbapenems bearing dicationic groups on the naphthosultamyl moiety was prepared and evaluated for activity against resistant gram-positive bacteria. Based on a combination of excellent in vitro anti