Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Joanne Heade"'
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1001 (2021)
The oral route of administration is by far the most convenient route, especially in the treatment of chronic conditions. However, many therapeutics present formulation difficulties which make them unsuitable for oral delivery. Recently, we synthesize
Externí odkaz:
https://doaj.org/article/648b800f325e41b3a0d88915270bbbe8
Autor:
Joanne Heade, Fiona McCartney, Miguel Chenlo, Olga Moreno Marro, Maja Severic, Robert Kent, Sinead B. Bleiel, Clara V. Alvarez, Brendan T. Griffin, David J. Brayden
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 656 (2021)
For many diabetics, daily, lifelong insulin injections are required to effectively manage blood glucose levels and the complications associated with the disease. This can be a burden and reduces patient quality of life. Our goal was to develop a more
Externí odkaz:
https://doaj.org/article/c01c94d1f0874249885cdebbad75c0fe
Publikováno v:
Pharmaceutics, Vol 11, Iss 2, p 78 (2019)
Salcaprozate sodium (SNAC) and sodium caprate (C10) are two of the most advanced intestinal permeation enhancers (PEs) that have been tested in clinical trials for oral delivery of macromolecules. Their effects on intestinal epithelia were studied fo
Externí odkaz:
https://doaj.org/article/61d28a5973274b619d400f667a20c77e
Publikováno v:
Pharmaceutics
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 1001, p 1001 (2021)
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 1001, p 1001 (2021)
The oral route of administration is by far the most convenient route, especially in the treatment of chronic conditions. However, many therapeutics present formulation difficulties which make them unsuitable for oral delivery. Recently, we synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb94ff4d2553d41512be9f74c188cff
In addition to their solubilizing properties, excipients used in lipid-based formulations can improve intestinal permeability of macromolecules. We determined whether admixing of medium-chain fatty acid (MCFA) permeation enhancers with a lipoidal exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bbabdef458b4334aee618852f1f6ef
Surfactant-based intestinal permeation enhancers (PEs) are constituents of several oral macromolecule formulations in clinical trials. This study examined the interaction of a test panel of surfactant-based-PEs with isolated rat colonic mucosae mount
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d83ab93eb5daeb55d5eb6ec47b238e0
Publikováno v:
Journal of pharmaceutical sciences. 107(6)
In addition to their solubilizing properties, excipients used in lipid-based formulations can improve intestinal permeability of macromolecules. We determined whether admixing of medium-chain fatty acid (MCFA) permeation enhancers with a lipoidal exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ddb2657c542ada93e2563142b200958
https://pubmed.ncbi.nlm.nih.gov/29462634
https://pubmed.ncbi.nlm.nih.gov/29462634
Publikováno v:
Peptides. 71
Two food-derived ACE inhibitory peptides, Ile-Pro-Pro (IPP) and Leu-Lys-Pro (LKP), may have potential as alternative treatments for treatment of mild- or pre-hypertension. Lack of stability to secretory and intracellular peptidases and poor permeabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6eed8af626e3e47a44841e85d7073a9
https://pubmed.ncbi.nlm.nih.gov/26048090
https://pubmed.ncbi.nlm.nih.gov/26048090
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 11, Iss 2, p 78 (2019)
Pharmaceutics, Vol 11, Iss 2, p 78 (2019)
Salcaprozate sodium (SNAC) and sodium caprate (C10) are two of the most advanced intestinal permeation enhancers (PEs) that have been tested in clinical trials for oral delivery of macromolecules. Their effects on intestinal epithelia were studied fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d980e4df5746bf19ed178864f4556d