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pro vyhledávání: '"Joanne Goranson-Siekierke"'
Autor:
Joanne Goranson-Siekierke, Ehmke Pohl, Randall K. Holmes, Tarmo Roosild, Michael K. Choi, Wim G. J. Hol
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 57:619-627
The diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae regulates the expression of the gene on corynebacteriophages that encodes diphtheria toxin (DT). Other genes regulated by DtxR include those that encode proteins involved in sider
Autor:
Wim G. J. Hol, Bjarni Pàll Ingason, Randall K. Holmes, Michael D. Feese, Joanne Goranson-Siekierke
Publikováno v:
Journal of Biological Chemistry. 276:5959-5966
Iron-dependent regulators are primary transcriptional regulators of virulence factors and iron scavenging systems that are important for infection by several bacterial pathogens. Here we present the 2.0-A crystal structure of the wild type iron-depen
Publikováno v:
Infection and Immunity. 67:1806-1811
The homodimeric diphtheria toxin repressor (DtxR) uses Fe 2+ as a corepressor, binds to iron-regulated promoters, and negatively regulates the syntheses of diphtheria toxin, corynebacterial siderophore, and several other Corynebacterium diphtheriae p
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 235