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of 5
pro vyhledávání: '"Joanne G.W. Nijhof"'
Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency
Autor:
Joanne G.W. Nijhof, Adriaan A. Mulder, Frank R. de Gruijl, Leon H.F. Mullenders, Carina van Pelt, David L. Mitchell
Publikováno v:
Carcinogenesis. 28:792-800
Ultraviolet (UV) radiation induces cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts (6-4PPs) in DNA, which through gene mutations (e.g. in P53) may lead to skin carcinogenesis. Upon chronic low-level UV exposure, certain basal cells in mo
Autor:
Joanne G.W. Nijhof, Rebecca J. Morris, Leon C. King, John C. Peckham, Raymond W. Tennant, Mayumi Ito, Amy Elmore, Margaret M. Humble, Carl D. Bortner, Norris D. Flagler, Linda D. Adams, Grace E. Kissling, Dhimant Desai, George Cotsarelis, Matthew Ehinger, Shantu Amin, Carol S. Trempus
Publikováno v:
Cancer research. 67(9)
The cell surface marker CD34 marks mouse hair follicle bulge cells, which have attributes of stem cells, including quiescence and multipotency. Using a CD34 knockout (KO) mouse, we tested the hypothesis that CD34 may participate in tumor development
Autor:
Aat M. Mulder, Esther M. Hoogervorst, Joanne G.W. Nijhof, Leon H.F. Mullenders, Frank R. de Gruijl, Ewoud N. Speksnijder
Publikováno v:
DNA repair. 6(11)
Ultraviolet (UV) radiation induces cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts ((6-4)PPs) in DNA, which may give rise to clusters of cells expressing mutant p53 (‘p53 patches’) and eventually to skin carcinomas. We have previousl
Autor:
Carina van Pelt, Frank R. de Gruijl, Leon H.F. Mullenders, Joanne G.W. Nijhof, Richard L. Boyd, Adam Giangreco, Kristin M. Braun, Hiroshi Kawamoto, Rein Willemze, Fiona M. Watt, Willem van Ewijk
Publikováno v:
Development (Cambridge, England). 133(15)
We describe a novel murine progenitor cell population localised to a previously uncharacterised region between sebaceous glands and the hair follicle bulge, defined by its reactivity to the thymic epithelial progenitor cell marker MTS24. MTS24 labels
Autor:
Joanne G.W. Nijhof, Carina van Pelt, Adriaan A. Mulder, David L. Mitchell, Leon H.F. Mullenders, Frank R. de Gruijl
Publikováno v:
Carcinogenesis; Apr2007, Vol. 28 Issue 4, p792-800, 9p