Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joanne F. Berson"'
Autor:
Michael S. Marks, Ilse Hurbain, Danielle Tenza, Graça Raposo, Steven T. Truschel, Penelope C. Thomas, Alexander C. Theos, Joanne F. Berson, Dawn C. Harper
Publikováno v:
Developmental Cell. 10:343-354
Cargo partitioning into intralumenal vesicles (ILVs) of multivesicular endosomes underlies such cellular processes as receptor downregulation, viral budding, and biogenesis of lysosome-related organelles such as melanosomes. We show that the melanoso
Publikováno v:
Journal of Investigative Dermatology. 121:821-830
Pmel17 is a approximately 100 kDa pigment cell specific glycoprotein that plays a crucial part in the morphogenesis of melanosome precursors. Anti-Pmel17 immunoprecipitates from metabolically pulse labeled melanoma cells and melanocytes contain, in a
Autor:
Alexander C. Theos, Dawn C. Harper, Michael S. Marks, Graça Raposo, Joanne F. Berson, Danielle Tenza
Publikováno v:
Journal of Cell Biology. 161:521-533
Lysosome-related organelles are cell type–specific intracellular compartments with distinct morphologies and functions. The molecular mechanisms governing the formation of their unique structural features are not known. Melanosomes and their precur
Publikováno v:
Molecular Biology of the Cell. 12:3451-3464
Melanosomes are tissue-specific organelles within which melanin is synthesized and stored. The melanocyte-specific glycoprotein Pmel17 is enriched in the lumen of premelanosomes, where it associates with characteristic striations of unknown compositi
Publikováno v:
The Journal of Cell Biology
Melanosomes and premelanosomes are lysosome-related organelles with a unique structure and cohort of resident proteins. We have positioned these organelles relative to endosomes and lysosomes in pigmented melanoma cells and melanocytes. Melanosome re
Publikováno v:
Journal of Biological Chemistry. 274:12780-12789
Distinct cytoplasmic sorting signals target integral membrane proteins to late endosomal compartments, but it is not known whether different signals direct targeting by different pathways. The availability of multiple pathways may permit some cell ty
Autor:
Julie D. Turner, Stephen C. Peiper, Trevor L. Hoffman, Michael J. Orsini, James A. Hoxie, Robert W. Doms, Joanne F. Berson, Benjamin J. Doranz, Lawrence F. Brass
Publikováno v:
Journal of Virology. 73:2752-2761
The interaction of the chemokine stromal cell-derived factor 1 (SDF-1) with its receptor CXCR4 is vital for cell trafficking during development, is capable of inhibiting human immunodeficiency virus type 1 (HIV-1) utilization of CXCR4 as a coreceptor
Autor:
Julie D. Turner, Robert W. Doms, Celia C. LaBranche, Thomas J. Matthews, Joanne F. Berson, Michael J. Endres, James A. Hoxie
Publikováno v:
Journal of Reproductive Immunology. 41:197-211
HIV entry is mediated by an interaction between CD4 and members of the chemokine receptor family of proteins. It is likely that CD4 induces conformational changes in the viral envelope glycoproteins that facilitate a subsequent interaction with the c
Autor:
Robert W. Doms, Joanne F. Berson
Publikováno v:
Seminars in Immunology. 10:237-248
Ten seven-transmembrane-domain G protein-coupled receptors have been identified that are functional HIV-1, HIV-2 and SIV coreceptors. However, the specific structures these receptors have in common that enable them to mediate HIV entry are unknown. S
Autor:
Matthew Sharron, Zhao-hai Lu, Yin-Hua Cen, Zi-xuan Wang, Yi Sun, Joanne F. Berson, Tian-yuan Zhang, Stephen C. Peiper
Publikováno v:
Journal of Biological Chemistry. 273:15007-15015
The interaction of human immunodeficiency virus type 1 (HIV-1) with CD4 and one of a cadre of chemokine receptors triggers conformational changes in the HIV-1 envelope (Env) glycoprotein that lead to membrane fusion. The coreceptor activity of the se