Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joanne E. Cook"'
Autor:
Joanne E. Cook, Maria V. D. Soares, Jeff M. Faint, Arne N. Akbar, W. Bergler, Jean M. Fletcher, Peter C. L. Beverley, Nicholas Hammerschmitt, Fiona J. Plunkett, Malcolm H.A. Rustin, Mike Salmon, Lavina L. Belaramani, Caroline S. Verbeke
Human-virus-specific CD8+ T cells that are found during primary infection have been studied almost exclusively in the peripheral blood, and it is unclear whether these cells are regulated in the same way as those in secondary lymphoid tissue. We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cd768401fc38e0795a4073d8419319
https://doi.org/10.1182/blood-2003-06-1791
https://doi.org/10.1182/blood-2003-06-1791
Autor:
C. H. Orteu, Sarah E. Jackson, Joanne E. Cook, Malcolm H.A. Rustin, Peter C. L. Beverley, Arne N. Akbar, Milica Vukmanovic-Stejic, Maria V. D. Soares, Jean M. Fletcher, Mike Salmon, John R. Reed, Graham R. Foster, Katie E. Birch
Publikováno v:
The Journal of Experimental Medicine
The extent of human memory T cell proliferation, differentiation, and telomere erosion that occurs after a single episode of immune challenge in vivo is unclear. To investigate this, we injected tuberculin purified protein derivative (PPD) into the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76e80dc3439e288df38f71e7056f8eb
https://ora.ox.ac.uk/objects/uuid:3023f882-5d77-4fd4-8315-32656e454d87
https://ora.ox.ac.uk/objects/uuid:3023f882-5d77-4fd4-8315-32656e454d87
Autor:
Janine Oldham, Diana L. Wallace, Marion Bérard, Joanne E. Cook, Arne N. Akbar, Peter C. L. Beverley, David F. Tough, Maria V. D. Soares
Publikováno v:
Immunology. 119:243-253
Interleukin (IL)-7 and IL-15 are cytokines implicated in homeostatic control of the peripheral CD8 T-cell pool. We compared the effects of IL-7 and IL-15 on survival and proliferation of purified human CD8+ T-cell subsets. Low concentrations of eithe
Autor:
Diana L, Wallace, Marion, Bérard, Maria V D, Soares, Janine, Oldham, Joanne E, Cook, Arne N, Akbar, David F, Tough, Peter C L, Beverley
Publikováno v:
Immunology. 119(2)
Interleukin (IL)-7 and IL-15 are cytokines implicated in homeostatic control of the peripheral CD8 T-cell pool. We compared the effects of IL-7 and IL-15 on survival and proliferation of purified human CD8+ T-cell subsets. Low concentrations of eithe
Autor:
Katie E. Birch, Mike Salmon, Malcolm H.A. Rustin, Joanne E. Cook, Sarah E. Jackson, Milica Vukmanovic-Stejic, Arne N. Akbar, Jean M. Fletcher, Pádraic J. Dunne
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(12)
Repeated antigenic encounter drives proliferation and differentiation of memory T cell pools. An important question is whether certain specific T cells may be driven eventually to exhaustion in elderly individuals since the human life expectancy is i
Autor:
Joanne E. Cook, Peter C. L. Beverley
Publikováno v:
Experimental gerontology. 36(3)
Heteroduplex analysis allows global analysis of T cell receptor clonality. This review outlines the method, compares it to other available techniques for the study of clonality and reviews current literature on how these are being used to investigate
Autor:
Milica Vukmanovic-Stejic, Yan Zhang, Peter C. L. Beverley, Joanne E. Cook, Arne N. Akbar, Joanne E. Masters, Leonie S. Taams, A McQuaid, Malcolm H.A. Rustin, Jean M. Fletcher, Derek C. Macallan
Publikováno v:
Journal of Clinical Investigation. 116:2828-2828
While memory T cells are maintained by continuous turnover, it is not clear how human regulatory CD4(+)CD45RO(+)CD25(hi) Foxp3(+) T lymphocyte populations persist throughout life. We therefore used deuterium labeling of cycling cells in vivo to deter