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of 9
pro vyhledávání: '"Joanne Clark-Matott"'
Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection
Autor:
Yevgeniya I. Shurubor, Marilena D’Aurelio, Joanne Clark-Matott, Elena P. Isakova, Yulia I. Deryabina, M. Flint Beal, Arthur J. L. Cooper, Boris F. Krasnikov
Publikováno v:
Molecules, Vol 22, Iss 9, p 1388 (2017)
Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) play essential roles in cell energy metabolism. Dysregulation of the biosynthesis and functioning of both compounds may contribute to various pathological conditions. We describe here a simple and s
Externí odkaz:
https://doaj.org/article/4c7eaf3ef90a4746864aeebced8fb847
Autor:
Yuka Okusha, Benjamin J. Lang, Ayesha Murshid, Thiago J. Borges, Kristina M. Holton, Joanne Clark-Matott, Sachin Doshi, Tsuneya Ikezu, Stuart K. Calderwood
Publikováno v:
Cell Stress and Chaperones. 27:479-483
Autor:
Yuka Okusha, Benjamin J. Lang, Ayesha Murshid, Thiago J. Borges, Kristina M. Holton, Joanne Clark-Matott, Sachin Doshi, Tsuneya Ikezu, Stuart K. Calderwood
Publikováno v:
Cell Stress Chaperones
Delivery of exogenous heat shock protein 90α (Hsp90α) and/or its induced expression in neural tissues has been suggested as a potential strategy to combat neurodegenerative disease. However, within a neurodegenerative context, a pro-inflammatory re
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-2 (2017)
Externí odkaz:
https://doaj.org/article/7d336d6c356540a492cf8882cff7e952
Autor:
Rebecca S. Taylor, Daniela Riveros, Janice A. Nagy, Benjamin Sanchez, David Simon, Joanne Clark-Matott, Seward B. Rutkove, Neeta A. Abraham
Publikováno v:
Muscle Nerve
Introduction Improved methods are needed to detect and quantify age-related muscle change. In this study we assessed the electrical properties of muscle impacted by acquired mitochondrial DNA mutations via the PolG mouse, which exhibits typical age-a
Autor:
Mark A. Tarnopolsky, Myron Flint Beal, Xiaoxing Ma, Ayesha Saleem, David Simon, Joanne Clark-Matott, Adeel Safdar, Ying Dai, Yevgeniya I. Shurubor
Publikováno v:
Neurobiology of Aging. 36:2972-2983
Mitochondrial DNA (mtDNA) mutator mice express a mutated form of mtDNA polymerase gamma that results an accelerated accumulation of somatic mtDNA mutations in association with a premature aging phenotype. An exploratory metabolomic analysis of cortic
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-2 (2017)
Autor:
Tanya Simuni, Bernard Ravina, Cornelia Kamp, John C. Morgan, Joanne Clark-Matott, Saloni Sharma, Liana Baker, Jordan J. Elm, G. Webster Ross, Marina E. Emborg, Susan R. Dunlop, David Simon, Allison K. Graebner
Publikováno v:
Journal of Parkinson's disease. 5(4)
Pioglitazone, an oral hypoglycemic agent, recently failed to show promise as a disease-modifying agent in a 44-week phase 2 placebo-controlled study in 210 Parkinson's disease (PD) subjects. We analyzed peripheral biomarkers, including leukocyte PGC-
Publikováno v:
Molecular Therapy. 24:S150
In the brain, expression of the transcription factor Pituitary Homeobox 3 or Paired-Like Homeodomain Transcription Factor 3 (PITX3) is crucial to the development and maintenance of dopaminergic neurons. During brain development, PITX3 functions in co