Zobrazeno 1 - 10 of 83 pro vyhledávání: '"Joanne C Masterson"'
1
Akademický článek
HIF-2α-dependent induction of miR-29a restrains TH1 activity during T cell dependent colitis
Autor: Agnieszka K. Czopik, Eóin N. McNamee, Victoria Vaughn, Xiangsheng Huang, In Hyuk Bang, Trent Clark, Yanyu Wang, Wei Ruan, Tom Nguyen, Joanne C. Masterson, Eunyoung Tak, Sandra Frank, Colm B. Collins, Howard Li, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Mark E. Gerich, Glenn T. Furuta, Xiaoyi Yuan, Anil K. Sood, Edwin F. de Zoeten, Holger K. Eltzschig
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Metabolic imbalance leading to inflammatory hypoxia and stabilization of hypoxia-inducible transcription factors (HIFs) is a hallmark of inflammatory bowel diseases. We hypothesize that HIF could be stabilized in CD4+ T cells during intestin
Externí odkaz: https://doaj.org/article/a669e42b23f44430a2592da34005a047
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2
Akademický článek
Esophageal microbiome in eosinophilic esophagitis.
Autor: J Kirk Harris, Rui Fang, Brandie D Wagner, Ha Na Choe, Caleb J Kelly, Shauna Schroeder, Wendy Moore, Mark J Stevens, Alyson Yeckes, Katie Amsden, Amir F Kagalwalla, Angelika Zalewski, Ikuo Hirano, Nirmala Gonsalves, Lauren N Henry, Joanne C Masterson, Charles E Robertson, Donald Y Leung, Norman R Pace, Steven J Ackerman, Glenn T Furuta, Sophie A Fillon
Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0128346 (2015)
The microbiome has been implicated in the pathogenesis of a number of allergic and inflammatory diseases. The mucosa affected by eosinophilic esophagitis (EoE) is composed of a stratified squamous epithelia and contains intraepithelial eosinophils. T
Externí odkaz: https://doaj.org/article/eaa5782acab94602bc11f3f4e1ca1a67
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3
Akademický článek
Novel device to sample the esophageal microbiome--the esophageal string test.
Autor: Sophie A Fillon, J Kirk Harris, Brandie D Wagner, Caleb J Kelly, Mark J Stevens, Wendy Moore, Rui Fang, Shauna Schroeder, Joanne C Masterson, Charles E Robertson, Norman R Pace, Steven J Ackerman, Glenn T Furuta
Publikováno v: PLoS ONE, Vol 7, Iss 9, p e42938 (2012)
A growing number of studies implicate the microbiome in the pathogenesis of intestinal inflammation. Previous work has shown that adults with esophagitis related to gastroesophageal reflux disease have altered esophageal microbiota compared to those
Externí odkaz: https://doaj.org/article/6f6d8892792645b5a6e7a1d53848bc47
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4
MicroRNA Dysregulation and Therapeutic Opportunities in Esophageal Diseases
Autor: Gary E. Markey, Claire L. Donohoe, Eoin N. McNamee, Joanne C. Masterson
Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology.
MicroRNAs (miRNAs) are a class of small endogenous RNA molecules between 18 to 25 nucleotides long. The primary function of miRNAs is in the posttranscriptional regulation of mRNA targets through RNA interference culminating in mRNA degradation or tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c62055133e0f1231e83e8db4d21f3d96
https://doi.org/10.1152/ajpgi.00184.2022
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6
Akademický článek
Heterogeneity of Intestinal Tissue Eosinophils: Potential Considerations for Next-Generation Eosinophil-Targeting Strategies
Autor: Joanne C. Masterson, Calies Menard-Katcher, Leigha D. Larsen, Glenn T. Furuta, Lisa A. Spencer
Publikováno v: Cells, Vol 10, Iss 2, p 426 (2021)
Eosinophils are implicated in the pathophysiology of a spectrum of eosinophil-associated diseases, including gastrointestinal eosinophilic diseases (EGIDs). Biologics that target the IL-5 pathway and are intended to ablate eosinophils have proved ben
Externí odkaz: https://doaj.org/article/644ca035b6c24af7ac815e4ff5f1dee2
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7
A Summary of the Meetings of the Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS) International Multidisciplinary Consensus
Autor: Christopher Ma, Alain M. Schoepfer, Ekaterina Safroneeva, Evan S. Dellon, Albert J. Bredenoord, Mirna Chehade, Margaret H. Collins, Brian G. Feagan, Glenn T. Furuta, Sandeep K. Gupta, Ikuo Hirano, Vipul Jairath, David A. Katzka, Rish K. Pai, Marc E. Rothenberg, Alex Straumann, Seema S. Aceves, Jeffrey A. Alexander, Nicoleta C. Arva, Dan Atkins, Luc Biedermann, Carine Blanchard, Antonella Cianferoni, Constanza Ciriza de los Rios, Frederic Clayton, Carla M. Davis, Nicola de Bortoli, Jorge A. Dias, Gary W. Falk, Robert M. Genta, Gisoo Ghaffari, Nirmala Gonsalves, Thomas Greuter, Russell Hopp, Karen S. Hsu Blatman, Elizabeth T. Jensen, Doug Johnston, Amir F. Kagalwalla, Helen M. Larsson, John Leung, Hubert Louis, Joanne C. Masterson, Calies Menard-Katcher, Paul A. Menard-Katcher, Fouad J. Moawad, Amanda B. Muir, Vincent A. Mukkada, Roberto Penagini, Robert D. Pesek, Kathryn Peterson, Philip E. Putnam, Alberto Ravelli, Edoardo V. Savarino, Christoph Schlag, Philipp Schreiner, Dagmar Simon, Thomas C. Smyrk, Jonathan M. Spergel, Tiffany H. Taft, Ingrid Terreehorst, Tim Vanuytsel, Carina Venter, Mario C. Vieira, Michael Vieth, Berber Vlieg-Boerstra, Ulrike von Arnim, Marjorie M. Walker, Joshua B. Wechsler, Philip Woodland, John T. Woosley, Guang-Yu Yang, Noam Zevit
Publikováno v: Gastroenterology, 161(3), 778-784. W.B. Saunders Ltd
The Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS) collaborators are a group of more than 70 gastroenterologists, pathologists, allergists, researchers, dietitians, psychologists, and methodologists who convened in a se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ae9fe7df4350648fc899671709fc91
https://doi.org/10.1053/j.gastro.2021.04.081
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