Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Joanne Berghout"'
Autor:
Yaa Ababio, Scott P. Kelly, Franca S Angeli, Joanne Berghout, Kui Huang, Kathy Liu, Sara Burns, Cynthia Senerchia, Rob Moccia, Gabriel C. Brooks
Publikováno v:
American Journal of Medicine Open, Vol 10, Iss , Pp 100038- (2023)
Background: Dilated cardiomyopathy (DCM) contributes significantly to heart failure prevalence, yet supporting epidemiologic data is sparse. This study sought to estimate the period prevalence of DCM and the proportion of idiopathic DCM in the United
Externí odkaz:
https://doaj.org/article/6d203e22dd34425cbe092f4429a9a700
Autor:
Nicolas Garnier, Joanne Berghout, Aldona Zygmunt, Deependra Singh, Kui A Huang, Waltraud Kantz, Carl Rudolf Blankart, Sandra Gillner, Jiawei Zhao, Richard Roettger, Christina Saier, Jan Kirschner, Joern Schenk, Leon Atkins, Nuala Ryan, Kaja Zarakowska, Jana Zschüntzsch, Michela Zuccolo, Matthias Müllenborn, Yuen-Sum Man, Liz Goodman, Marie Trad, Anne Sophie Chalandon, Stefaan Sansen, Maria Martinez-Fresno, Shirlene Badger, Rudolf Walther van Olden, Robert Rothmann, Patrick Lehner, Christof Tschohl, Ludovic Baillon, Gulcin Gumus, Edith Gross, Rumen Stefanov, Georgi Iskrov, Ralitsa Raycheva, Kostadin Kostadinov, Elena Mitova, Moshe Einhorn, Yaron Einhorn, Josef Schepers, Miriam Hübner, Frauke Alves, Rowan Iskandar, Rudolf Mayer, Alessandra Renieri, Aneta Piperkova, Ivo Gut, Sergi Beltran, Mads Emil Matthiesen, Marion Poetz, Mats Hansson, Regina Trollmann, Emanuele Agolini, Silvia Ottombrino, Antonio Novelli, Enrico Bertini, Rita Selvatici, Marianna Farnè, Fernanda Fortunato, Alessandra Ferlini
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293503 (2023)
Since 72% of rare diseases are genetic in origin and mostly paediatrics, genetic newborn screening represents a diagnostic "window of opportunity". Therefore, many gNBS initiatives started in different European countries. Screen4Care is a research pr
Externí odkaz:
https://doaj.org/article/b1398ce8c27f41afbbe124544bb3d5b6
Autor:
Samir Rachid Zaim, Colleen Kenost, Joanne Berghout, Wesley Chiu, Liam Wilson, Hao Helen Zhang, Yves A. Lussier
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-22 (2020)
Abstract Background In this era of data science-driven bioinformatics, machine learning research has focused on feature selection as users want more interpretation and post-hoc analyses for biomarker detection. However, when there are more features (
Externí odkaz:
https://doaj.org/article/f79d3e96648b4b87a411af504b84c054
Autor:
Samir Rachid Zaim, Colleen Kenost, Joanne Berghout, Francesca Vitali, Helen Hao Zhang, Yves A. Lussier
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S5, Pp 1-15 (2019)
Abstract Background Gene expression profiling has benefited medicine by providing clinically relevant insights at the molecular candidate and systems levels. However, to adopt a more ‘precision’ approach that integrates individual variability inc
Externí odkaz:
https://doaj.org/article/d8c5db5cc7e148b698ae1058165d65a2
Autor:
Haiquan Li, Jungwei Fan, Francesca Vitali, Joanne Berghout, Dillon Aberasturi, Jianrong Li, Liam Wilson, Wesley Chiu, Minsu Pumarejo, Jiali Han, Colleen Kenost, Pradeep C. Koripella, Nima Pouladi, Dean Billheimer, Edward J. Bedrick, Yves A. Lussier
Publikováno v:
BMC Medical Genomics, Vol 11, Iss S6, Pp 1-15 (2018)
Abstract Background Forty-two percent of patients experience disease comorbidity, contributing substantially to mortality rates and increased healthcare costs. Yet, the possibility of underlying shared mechanisms for diseases remains not well establi
Externí odkaz:
https://doaj.org/article/7f9da742a05c4ac682be3d885ab0f45b
Autor:
Samir Rachid Zaim, Colleen Kenost, Joanne Berghout, Wesley Chiu, Liam Wilson, Hao Helen Zhang, Yves A. Lussier
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/67c94811c9134ae2985bfe11359ad101
Autor:
Qike Li, A. Grant Schissler, Vincent Gardeux, Ikbel Achour, Colleen Kenost, Joanne Berghout, Haiquan Li, Hao Helen Zhang, Yves A. Lussier
Publikováno v:
BMC Medical Genomics, Vol 10, Iss S1, Pp 5-16 (2017)
Abstract Background Transcriptome analytic tools are commonly used across patient cohorts to develop drugs and predict clinical outcomes. However, as precision medicine pursues more accurate and individualized treatment decisions, these methods are n
Externí odkaz:
https://doaj.org/article/e41206918a824ae38f85edb7960d8b1f
Autor:
Joanne Berghout, David Langlais, Irena Radovanovic, Mifong Tam, John D MacMicking, Mary M Stevenson, Philippe Gros
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003491 (2013)
Interferon Regulatory Factor 8 (IRF8) is required for development, maturation and expression of anti-microbial defenses of myeloid cells. BXH2 mice harbor a severely hypomorphic allele at Irf8 (Irf8(R294C)) that causes susceptibility to infection wit
Externí odkaz:
https://doaj.org/article/a35d16f33c834cc29282f236061241b1
Autor:
Silayuv E Bongfen, Ian-Gael Rodrigue-Gervais, Joanne Berghout, Sabrina Torre, Pablo Cingolani, Sean A Wiltshire, Gabriel A Leiva-Torres, Louis Letourneau, Robert Sladek, Mathieu Blanchette, Mark Lathrop, Marcel A Behr, Samantha Gruenheid, Silvia M Vidal, Maya Saleh, Philippe Gros
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31012 (2012)
Cerebral malaria (CM) is a lethal neurological complication of malaria. We implemented a genome-wide screen in mutagenized mice to identify host proteins involved in CM pathogenesis and whose inhibition may be of therapeutic value. One pedigree (P48)
Externí odkaz:
https://doaj.org/article/f2ebc22ce44b429ab6dc2ed68254a468
Autor:
Liam Wilson, Yves A. Lussier, Jiali Han, Colleen Kenost, Nima Pouladi, Francesca Vitali, Joanne Berghout, Minsu Pumarejo, Dean Billheimer, Pradeep C. Koripella, Jianrong Li, Dillon Aberasturi, Wesley Chiu, Jungwei Fan, Haiquan Li, Edward J. Bedrick
Publikováno v:
BMC Medical Genomics, Vol 11, Iss S6, Pp 1-15 (2018)
BMC Medical Genomics
BMC Medical Genomics
Background Forty-two percent of patients experience disease comorbidity, contributing substantially to mortality rates and increased healthcare costs. Yet, the possibility of underlying shared mechanisms for diseases remains not well established, and