Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Joanne Baffic"'
Autor:
Carl P. Sparrow, Sushma Patel, Joanne Baffic, Yu-Sheng Chao, Melba Hernandez, My-Hanh Lam, Judy Montenegro, Samuel D. Wright, Patricia A. Detmers
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 10, Pp 1747-1757 (1999)
The fluorescent cholesterol analog 22-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-23,24-bisnor-5-cholen-3β-ol (fluoresterol) was characterized as a tool for exploring the biochemistry and cell biology of intestinal cholesterol absorption. Hamsters
Externí odkaz:
https://doaj.org/article/801c013a20924848bc1b4d95d043787d
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 11, Pp 2201-2208 (1998)
Monocytes can be activated by incubation with opsonized zymosan (Zop), and under these conditions can oxidize low density lipoprotein (LDL). We have characterized the biochemical changes in the lipoprotein after this oxidation. We found that monocyte
Externí odkaz:
https://doaj.org/article/f4c0b350422e47f0a8438840d1172ec4
Autor:
Joanne Baffic, Yu-Sheng Chao, A. Brian Jones, Weiguo Liu, Steve Chen, John G. Menke, Carl P. Sparrow, Melba Hernandez, Sherrie X McCormick, Xiaohua Li, Aileen Bouffard, Tom S. Chen, John G. Ondeyka, James F. Dropinski, Jianhua Wang, Neelam Sharma, Sheo B. Singh, Karen L. MacNaul, Charlotte Burton, Nancy S. Hayes, My-Hanh Lam
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2824-2828
Liver X receptors are nuclear receptors that regulate metabolism of cholesterol. They are activated by oxysterols resulting in increased transcription of the ABCA1 gene, promoting cholesterol efflux and HDL formation. We have identified podocarpic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91291554a85a4cdd26920f44ff0310f
https://doi.org/10.1016/j.bmcl.2005.03.100
https://doi.org/10.1016/j.bmcl.2005.03.100
Autor:
Joel P. Berger, Melba Hernandez, Wei Han, Carl P. Sparrow, Chhabi Biswas, Joanne Baffic, James V. Heck, Pei-Ran Wang, Samuel D. Wright, Gaochao Zhou, Yu-Sheng Chao, Qiu Guo, David E. Moller, Karen L. MacNaul, Denise P. Milot, Ranjit C. Desai, Neelam Sharma, Soumya P. Sahoo, Marc C. Ippolito, My-Hanh Lam, Linda J. Kelly, Margaret Wu, Thomas W. Doebber
Publikováno v:
Endocrinology. 145:1640-1648
Patients with type 2 diabetes mellitus exhibit hyperglycemia and dyslipidemia as well as a markedly increased incidence of atherosclerotic cardiovascular disease. Here we report the characterization of a novel arylthiazolidinedione capable of lowerin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175dcc68b6952d7d3f93601399fd22f8
https://doi.org/10.1210/en.2003-1270
https://doi.org/10.1210/en.2003-1270
Autor:
S. Patel, Joanne Baffic, Yu-Sheng Chao, Carl P. Sparrow, Samuel D. Wright, Melba Hernandez, My-Hanh Lam, Judy Montenegro, Patricia A. Detmers
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 10, Pp 1747-1757 (1999)
The fluorescent cholesterol analog 22-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-23,24-bisnor-5-cholen-3β-ol (fluoresterol) was characterized as a tool for exploring the biochemistry and cell biology of intestinal cholesterol absorption. Hamsters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0bf3813811053aa8275c319d0f30c1
https://doi.org/10.1016/s0022-2275(20)34891-4
https://doi.org/10.1016/s0022-2275(20)34891-4
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 11, Pp 2201-2208 (1998)
Monocytes can be activated by incubation with opsonized zymosan (Zop), and under these conditions can oxidize low density lipoprotein (LDL). We have characterized the biochemical changes in the lipoprotein after this oxidation. We found that monocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b73a3a270f9553612951e1d816c3ee2
http://www.sciencedirect.com/science/article/pii/S0022227520324755
http://www.sciencedirect.com/science/article/pii/S0022227520324755
Autor:
Samuel D. Wright, David E. Moller, Gaochao Zhou, Karen L. MacNaul, Patrick Xin, Carl P. Sparrow, Yu-Sheng Chao, My-Hanh Lam, Soumya P. Sahoo, Azriel Schmidt, Alex Elbrecht, Nancy S. Hayes, Linda J. Kelly, John G. Menke, Jianhua Wang, Joanne Baffic
Publikováno v:
Endocrinology. 143(7)
The liver X receptors, LXRalpha and LXRbeta, are members of the nuclear receptor superfamily. Originally identified as orphans, both receptor subtypes have since been shown to be activated by naturally occurring oxysterols. LXRalpha knockout mice fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27908b7c67929342564677bdc5822a4e
https://pubmed.ncbi.nlm.nih.gov/12072387
https://pubmed.ncbi.nlm.nih.gov/12072387
Autor:
John G. Ondeyka, Nancy S. Hayes, Xuan Fu, Carl P. Sparrow, Joanne Baffic, Gaochao Zhou, A. Brian Jones, Samuel D. Wright, Alan D. Adams, Sheo B. Singh, Jianhua Wang, John G. Menke, My-Hanh Lam, Erik G. Lund, David E. Moller, Karen L. MacNaul
Publikováno v:
The Journal of biological chemistry. 277(12)
The LXR nuclear receptors are intracellular sensors of cholesterol excess and are activated by various oxysterols. LXRs have been shown to regulate multiple genes of lipid metabolism, including ABCA1 (formerly known as ABC1). ABCA1 is a lipid pump th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5964d5a7150057e4a1863f88291bddf0
https://pubmed.ncbi.nlm.nih.gov/11790770
https://pubmed.ncbi.nlm.nih.gov/11790770
Autor:
Robert W. Marquis, Catherine A. Cullinan, Johan Auwerx, Conrad Santini, Nathalie Hennuyer, Carl P. Sparrow, Gregory D. Berger, David E. Moller, Richard L. Tolman, Joanne Baffic, Roy G. Smith, Catherine Fievet, Joel P. Berger, Hélène Duez, Julia Peinado-Onsurbe, Mark D. Leibowitz
Publikováno v:
FEBS letters. 473(3)
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors, which heterodimerize with the retinoid X receptor and bind to peroxisome proliferator response elements in the promoters of regulated genes. Despite the wealth of information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e820804a56ba06d07effd08987f0cf
https://pubmed.ncbi.nlm.nih.gov/10818235
https://pubmed.ncbi.nlm.nih.gov/10818235