Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Joanne, Trgovcich"'
Autor:
Laura M. Carlson, Krista Christensen, Sharon K. Sagiv, Pradeep Rajan, Carolyn R. Klocke, Pamela J. Lein, Evan Coffman, Rachel M. Shaffer, Erin E. Yost, Xabier Arzuaga, Pam Factor-Litvak, Alexander Sergeev, Michal Toborek, Michael S. Bloom, Joanne Trgovcich, Todd A. Jusko, Larry Robertson, John D. Meeker, Aileen F. Keating, Robyn Blain, Raquel A. Silva, Samantha Snow, Cynthia Lin, Kelly Shipkowski, Brandall Ingle, Geniece M. Lehmann
Assessing health outcomes associated with exposure to polychlorinated biphenyls (PCBs) is important given their persistent and ubiquitous nature. PCBs are classified as a Group 1 carcinogen, but the full range of potential noncancer health effects fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8243a2f0fe88dad74fee76fd1a8acd
https://escholarship.org/uc/item/4s17623s
https://escholarship.org/uc/item/4s17623s
Publikováno v:
Viruses, Vol 6, Iss 4, Pp 1502-1524 (2014)
Interferons (IFNs) activate the first lines of defense against viruses, and promote innate and adaptive immune responses to viruses. We report that the immediate early 1 (IE1) protein of human cytomegalovirus (HCMV) disrupts signaling by IFNγ. The c
Externí odkaz:
https://doaj.org/article/12704c7251f24803b16ae4d7ac7c58ee
Autor:
Joanne Trgovcich, Michelle Kincaid, Alicia Thomas, Marion Griessl, Peter Zimmerman, Varun Dwivedi, Valerie Bergdall, Paul Klenerman, Charles H Cook
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
Cytomegalovirus (CMV) has been shown to induce large populations of CD8 T-effector memory cells that unlike central memory persist in large quantities following infection, a phenomenon commonly termed "memory inflation". Although murine models to dat
Externí odkaz:
https://doaj.org/article/e60f78e315ab4ba0876ac49a87c89392
Autor:
Vanda Juranic Lisnic, Marina Babic Cac, Berislav Lisnic, Tihana Trsan, Adam Mefferd, Chitrangada Das Mukhopadhyay, Charles H Cook, Stipan Jonjic, Joanne Trgovcich
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003611 (2013)
Major gaps in our knowledge of pathogen genes and how these gene products interact with host gene products to cause disease represent a major obstacle to progress in vaccine and antiviral drug development for the herpesviruses. To begin to bridge the
Externí odkaz:
https://doaj.org/article/396d831f7630403caf723175c1d1a3c7
Autor:
Lisa Marcinowski, Mélanie Tanguy, Astrid Krmpotic, Bernd Rädle, Vanda J Lisnić, Lee Tuddenham, Béatrice Chane-Woon-Ming, Zsolt Ruzsics, Florian Erhard, Corinna Benkartek, Marina Babic, Ralf Zimmer, Joanne Trgovcich, Ulrich H Koszinowski, Stipan Jonjic, Sébastien Pfeffer, Lars Dölken
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002510 (2012)
Cytomegaloviruses express large amounts of viral miRNAs during lytic infection, yet, they only modestly alter the cellular miRNA profile. The most prominent alteration upon lytic murine cytomegalovirus (MCMV) infection is the rapid degradation of the
Externí odkaz:
https://doaj.org/article/bc6b3dba698d4ee5a8e3e24afff86ee8
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2277 (2008)
PML gene was discovered as a fusion partner with retinoic acid receptor (RAR) alpha in the t(15:17) chromosomal translocation associated with acute promyelocytic leukemia (APL). Nuclear PML protein has been implicated in cell growth, tumor suppressio
Externí odkaz:
https://doaj.org/article/d2ee0c5f804b475690349e80ea33183d
Autor:
Michael Gutknecht, Sara Byrd, Varun Dwivedi, Charles H. Cook, Marion Griessl, Sara A. Mansfield, Joanne Trgovcich
Publikováno v:
Journal of Medical Virology. 88:1408-1416
Roughly 1/3rd of immune competent patients will reactivate latent cytomegalovirus (CMV) during critical illness. There are no standard methods to detect reactivation, and some investigators have postulated that presence of DNA in BAL fluid is indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50a8e49e9fa8cf28b6b6b0d7f2c5d6a4
https://doi.org/10.1002/jmv.24472
https://doi.org/10.1002/jmv.24472
Publikováno v:
Journal of Cellular and Molecular Medicine
MicroRNAs (miRNAs) have emerged as important regulators in the post-transcriptional control of gene expression. The discovery of their presence not only in tissues but also in extratissular fluids, including blood, urine and cerebro-spinal fluid, tog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f50cfb7d21c46f86addee4cd6977a32
https://doi.org/10.1111/jcmm.12236
https://doi.org/10.1111/jcmm.12236
Autor:
Alicia Thomas, Peter D. Zimmerman, Paul Klenerman, Marion Griessl, Joanne Trgovcich, Valerie K. Bergdall, Michelle Kincaid, Varun Dwivedi, Charles H. Cook
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
Cytomegalovirus (CMV) has been shown to induce large populations of CD8 T-effector memory cells that unlike central memory persist in large quantities following infection, a phenomenon commonly termed “memory inflation”. Although murine models to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8781a5ed43d89a47e446c929a43519
http://europepmc.org/articles/PMC5117776
http://europepmc.org/articles/PMC5117776
Autor:
Stuart Sims, Michelle Kincaid, Jonathan E. Campbell, Joanne Trgovcich, Charles H. Cook, Peter D. Zimmerman, Paul Klenerman
Heterologous antigen encounters can induce transient T-memory contraction, allowing cytomegaloviral recrudescence in latently infected immunocompetent hosts. It is clear that latent CMV can reactivate in immunocompetent individuals, but the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cdb9b4f16d7bd0f7ed380d669482e9
https://doi.org/10.1189/jlb.1211635
https://doi.org/10.1189/jlb.1211635