Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joanna Wegrzyn Woltosz"'
Autor:
Christopher P. Venner, Joanna Wegrzyn Woltosz, Thomas J. Nevill, H. Joachim Deeg, Gisela Caceres, Uwe Platzbecker, Bart L. Scott, Lubomir Sokol, Sandy Sung, Alan F. List, Aly Karsan
Publikováno v:
Haematologica, Vol 98, Iss 3 (2013)
We examined whether lenalidomide exposure up-regulates miRNAs and mRNAs, previously shown to play a role in the disease phenotype of del(5q) myelodysplastic syndrome, in pre-treatment CD34+ marrow cells. We hypothesized that increased expression woul
Externí odkaz:
https://doaj.org/article/037dbe181834463da7611ea11427fd02
Autor:
Tony Hui, Qi Cao, Joanna Wegrzyn-Woltosz, Kieran O'Neill, Colin A. Hammond, David J.H.F. Knapp, Emma Laks, Michelle Moksa, Samuel Aparicio, Connie J. Eaves, Aly Karsan, Martin Hirst
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 578-592 (2018)
Summary: Increasing evidence of functional and transcriptional heterogeneity in phenotypically similar cells examined individually has prompted interest in obtaining parallel methylome data. We describe the development and application of such a proto
Externí odkaz:
https://doaj.org/article/2e0fa26ae7804df3820af3c233fd2998
Autor:
Patricia Umlandt, Linda Chang, Melody Lu, Jeremy Parker, Megan Fuller, Joanna Wegrzyn-Woltosz, Aly Karsan, Jenny Li, Jeffrey C. F. Lam, Aparna Gopal, Rawa Ibrahim
Activation of inflammatory pathways is associated with bone marrow failure syndromes, but how specific molecules impact on the marrow microenvironment is not well elucidated. We report a novel role for the miR-145 target, Toll/Interleukin-1 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab03d8a626bc0630fa0c428898cc251
Autor:
Samuel Aparicio, Emma Laks, Qi Cao, Aly Karsan, Colin A. Hammond, Joanna Wegrzyn-Woltosz, Michelle Moksa, Martin Hirst, Connie J. Eaves, David J.H.F. Knapp, Kieran O'Neill, Tony Hui
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 11, Iss 2, Pp 578-592 (2018)
Stem Cell Reports, Vol 11, Iss 2, Pp 578-592 (2018)
Summary Increasing evidence of functional and transcriptional heterogeneity in phenotypically similar cells examined individually has prompted interest in obtaining parallel methylome data. We describe the development and application of such a protoc
Molecular etiology of an indolent lymphoproliferative disorder determined by whole-genome sequencing
Autor:
Janessa Laskin, Aly Karsan, Kerry J. Savage, Marco A. Marra, Joanna Wegrzyn-Woltosz, Jacqueline E. Schein, Andrew P. Weng, Steven J.M. Jones, Randy D. Gascoyne, Richard A. Moore, Yongjun Zhao, Yaoqing Shen, Yvonne Y. Li, Jeremy Parker, Erin Pleasance
Publikováno v:
Cold Spring Harbor Molecular Case Studies
In an attempt to assess potential treatment options, whole-genome and transcriptome sequencing were performed on a patient with an unclassifiable small lymphoproliferative disorder. Variants from genome sequencing were prioritized using a combination
Autor:
Jeffrey C. F. Lam, Megan Fuller, Rawa Ibrahim, Kate Slowski, Joanna Wegrzyn-Woltosz, Aly Karsan, Patricia Umlandt
Publikováno v:
Blood. 124:527-527
Myelodysplastic syndromes (MDS) are a collection of hematopoietic malignancies in which genomic abnormalities within the hematopoietic stem cell (HSC) compartment results in dysplasia of the marrow cells and ineffective hematopoiesis. As a result, th
Publikováno v:
Experimental Hematology. 41:S49