Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Joanna Szmydynger-Chodobska"'
Autor:
Steven W. Threlkeld, Emma Morales Cestero, John Marshall, Joanna Szmydynger-Chodobska, Adam Chodobski
Publikováno v:
Neurotrauma Reports, Vol 3, Iss 1, Pp 207-216 (2022)
Traumatic brain injury (TBI) exacts significant neurological and financial costs on patients and their families. In adult patients with moderate-to-severe TBI, central auditory impairments have been reported. These auditory impairments may interfere
Externí odkaz:
https://doaj.org/article/c59954c170684b86bf689b2137525f41
Autor:
Adam Chodobski, Jean-François Ghersi-Egea, Jane Preston-Kennedy, Zoran Redzic, Nathalie Strazielle, Joanna Szmydynger-Chodobska, Robert G. Thorne
Publikováno v:
Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-6 (2019)
Abstract This article highlights the scientific achievements, professional career, and personal interactions of Malcolm B. Segal who passed away in July this year. Born in 1937 in Goodmayes, Essex, UK, Segal rose to the Chairman position in the Divis
Externí odkaz:
https://doaj.org/article/4de1240650bc4da18a6f3d0dca9cdbf1
Autor:
John Marshall, Joanna Szmydynger-Chodobska, Mengia S. Rioult-Pedotti, Kara Lau, Andrea T. Chin, Siva K. Reddy Kotla, Rakesh Kumar Tiwari, Keykavous Parang, Steven W. Threlkeld, Adam Chodobski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Brain-derived neurotrophic factor (BDNF), a key player in regulating synaptic strength and learning, is dysregulated following traumatic brain injury (TBI), suggesting that stimulation of BDNF signaling pathways may facilitate functional rec
Externí odkaz:
https://doaj.org/article/44c107a080a54523a1e0b98d597f1b43
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167677 (2016)
The pathophysiological mechanisms underlying mild traumatic brain injury (mTBI) are not well understood, but likely involve neuroinflammation. Here the controlled cortical impact model of mTBI in rats was used to test this hypothesis. Mild TBI caused
Externí odkaz:
https://doaj.org/article/a9e390cac5684b5e945ccc5ee52ff7c3
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79328 (2013)
Several lines of evidence indicate that the blood-cerebrospinal fluid barrier (BCSFB), which primarily resides in the choroid plexus (CP), plays a significant pathophysiological role not only in neuroinflammatory diseases, such as multiple sclerosis,
Externí odkaz:
https://doaj.org/article/310cc626b9ff44d6922d91d1057ed74d
Autor:
Adam Chodobski, Gregory D. Jay, Tannin A. Schmidt, Nathalie Strazielle, Marissa Bennett, Holly A. Richendrfer, Hyung Jin Lee, Emma Morales Cestero, Joanna Szmydynger-Chodobska, Jean-François Ghersi-Egea, Steven W. Threlkeld, Andrea T. Chin
Publikováno v:
Journal of Neurotrauma
Neuroinflammation and dysfunction of the blood–brain barrier (BBB) are two prominent mechanisms of secondary injury in neurotrauma. It has been suggested that Toll-like receptors (TLRs) play important roles in initiating and propagating neuroinflam
Autor:
Jean-François Ghersi-Egea, Robert G. Thorne, Nathalie Strazielle, Adam Chodobski, Jane Preston-Kennedy, Zoran B. Redzic, Joanna Szmydynger-Chodobska
Publikováno v:
Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-6 (2019)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
This article highlights the scientific achievements, professional career, and personal interactions of Malcolm B. Segal who passed away in July this year. Born in 1937 in Goodmayes, Essex, UK, Segal rose to the Chairman position in the Division of Ph
Autor:
Nicole Glaser, Jeff E. Schunk, Shara R. Bialo, Jonathan E. Bennett, Rongzi Shan, Kimberly S. Quayle, Joanna Szmydynger-Chodobska, Adam Chodobski, Nathan Kuppermann, T. Charles Casper, Aris Garro, Arleta Rewers
Publikováno v:
Pediatric Diabetes. 18:95-102
Background and objective Matrix metalloproteinases (MMPs) mediate blood–brain barrier dysfunction in inflammatory disease states. Our objective was to compare circulating MMPs in children with diabetic ketoacidosis (DKA) to children with type 1 dia
Autor:
Joanna Szmydynger-Chodobska, Adam Chodobski, Mengia S. Rioult-Pedotti, Keykavous Parang, John Marshall, Andrea T. Chin, Rakesh Tiwari, Steven W. Threlkeld, Kara Lau, Siva K. Reddy Kotla
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Brain-derived neurotrophic factor (BDNF), a key player in regulating synaptic strength and learning, is dysregulated following traumatic brain injury (TBI), suggesting that stimulation of BDNF signaling pathways may facilitate functional recovery. Th
Publikováno v:
Translational Stroke Research. 2:492-516
The blood-brain barrier (BBB) is formed by tightly connected cerebrovascular endothelial cells, but its normal function also depends on paracrine interactions between the brain endothelium and closely located glia. There is a growing consensus that b