Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joanna Szczęśniak"'
Autor:
Andrzej Gondela, Marcin Leś, Maciej Mikulski, Łukasz Włoszczak, Frank Becker, Kamila Olech, Shivapriya Ramaswamy, Marcin Król, Henryk Pawlik, Christian Herhaus, Jose Alvarez, Joanna Szczęśniak, Heike Schilke, Paulina Niedziejko, Lindsey Crowley, Roberta Ferretti, Mireille Krier, Pamela Wahra, Pia Böpple, Timo Heinrich, Justyna Martyka, Ewa Sitek, Karol Zuchowicz, Ada Sala-Hojman, Anna Bartosik, Stefano Minguzzi, Łukasz Dudek, Frank Czauderna, Mateusz Nowak, Ansgar Wegener, Michal Galezowski, Carl Petersson, Sven Jäckel
Publikováno v:
Journal of medicinal chemistry. 64(16)
Due to increased lactate production during glucose metabolism, tumor cells heavily rely on efficient lactate transport to avoid intracellular lactate accumulation and acidification. Monocarboxylate transporter 4 (MCT4/SLC16A3) is a lactate transporte
Autor:
Jose Alvarez, Agnieszka Dreas, Kamila Kozłowska, Kinga Michalik, Magdalena Zastawna, Anna Wrobel, Karol Zuchowicz, Andrzej Mazan, Peter Littlewood, Justyna Martyka, Magdalena Łośko, Tomasz Rzymski, Agnieszka Sroka-Porada, Paulina Niedziejko, Urszula Kulesza, Luigi Stasi, Joanna Szczęśniak, Krzysztof Brzózka, Adam Radzimierski, Katarzyna Wnuk-Lipinska, Katarzyna Wiklik, Anna Kowal
Publikováno v:
Cancer Research. 80:3656-3656
Background: Synthetic lethality is one of the most innovative approaches for selective targeting of cancer cells with defined genetic background. SMARCA2 and SMARCA4 are two mutually exclusive helicase/ATPase catalytic subunits belonging to SWI/SNF c