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pro vyhledávání: '"Joanna Summerbell"'
Publikováno v:
British Journal of Clinical Pharmacology. 36:399-404
1. The aims of this study were two-fold. First, to define ranges of blood esterase activities in three groups, namely young subjects, fit community dwelling elderly and frail, chronically hospitalised elderly subjects, and second, to determine whethe
Autor:
Joanna Summerbell, Catherine Yelland, Hilary Wynne, Barbara Herd, K. W. Woodhouse, Elizabeth Nicholson
Publikováno v:
Age and ageing. 20(1)
The activity of the phase 1 enzyme aspirin esterase was studied in liver tissue from 16 patients, aged 45-88 years. No correlation between age and enzyme activity was found in post-mitochondrial, cytosolic and microsomal fractions. These results prov
Publikováno v:
Age and ageing. 19(2)
The kinetics of the phase I enzyme aspirin esterase were estimated in plasma from ten young volunteers, seven healthy elderly volunteers, and in ten frail elderly subjects. Maximal reaction velocity at enzyme saturation (vmax) was similar in young an