Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Joanna Sarzynska"'
Publikováno v:
ACS Omega, Vol 4, Iss 2, Pp 3029-3044 (2019)
Externí odkaz:
https://doaj.org/article/fbfad514685a45a191317e65c759701a
Autor:
Lucyna Budzko, Paulina Jackowiak, Karol Kamel, Joanna Sarzynska, Janusz M. Bujnicki, Marek Figlerowicz
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Activation-induced cytidine deaminase (AID) is known for its established role in antibody production. AID induces the diversification of antibodies by deaminating deoxycytidine (C) within immunoglobulin genes. The capacity of AID to deaminat
Externí odkaz:
https://doaj.org/article/8ffed197854841b4b662d412e8d4c692
Pseudouridine and N1-methylpseudouridine are the key modifications in the field of mRNA therapeutics and vaccine research. The accuracy of the design and development of therapeutic RNAs containing such modifications requires the accuracy of the secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff45bc7243c1fd5d32ae1a9344566cca
https://doi.org/10.26434/chemrxiv-2023-zblrz-v4
https://doi.org/10.26434/chemrxiv-2023-zblrz-v4
Pseudouridine and N1-methylpseudouridine are the key modifications in the field of mRNA therapeutics and vaccine research. The accuracy of the design and development of therapeutic RNAs containing such modifications requires the accuracy of the secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f2990e729f172942e0b705cb8888a8
https://doi.org/10.26434/chemrxiv-2023-zblrz
https://doi.org/10.26434/chemrxiv-2023-zblrz
Pseudouridine (Ψ) is one of the most common post-transcriptional modifications in RNA and has been known to play significant roles in several crucial biological processes. The N1-methyl derivative of pseudouridine i.e N1-methylpseudouridine has also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd6e26b86d944a7f392532e987d6c428
https://doi.org/10.1101/2023.03.19.533340
https://doi.org/10.1101/2023.03.19.533340
Autor:
Kamil Luwanski, Vladyslav Hlushchenko, Mariusz Popenda, Tomasz Zok, Joanna Sarzynska, Daniil Martsich, Marta Szachniuk, Maciej Antczak
Publikováno v:
Nucleic Acids Research. 50:W663-W669
Advances in experimental and computational techniques enable the exploration of large and complex RNA 3D structures. These, in turn, reveal previously unstudied properties and motifs not characteristic for small molecules with simple architectures. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f670d0c00f0222967883431ff1a80a75
https://doi.org/10.1093/nar/gkac218
https://doi.org/10.1093/nar/gkac218
Publikováno v:
Progress in Biophysics and Molecular Biology. :21-52
Inosine is one of the most common post-transcriptional modifications. Since its discovery, it has been noted for its ability to contribute to non-Watson-Crick interactions within RNA. Rapidly accumulating evidence points to the widespread generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f762af6684a74eb0817043f8f9d7f3b
https://doi.org/10.1016/j.pbiomolbio.2022.01.001
https://doi.org/10.1016/j.pbiomolbio.2022.01.001
LNA-induced dynamic stability in a therapeutic aptamer: insights from molecular dynamics simulations
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 41:2221-2230
Modulation of structural and thermodynamic properties of nucleic acids with synthetic modifications is a promising area of research with possible applications in nanotechnology and nanotherapeutics. Locked nucleic acid (LNA) is one such modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fca9be575c2dc717c78724b60e255a0
https://doi.org/10.1080/07391102.2022.2029567
https://doi.org/10.1080/07391102.2022.2029567
Inosine is one of the most abundant post-transcriptionally modified ribonucleosides which is known to play a major role in several important biological processes and is of great therapeutic importance. The growing importance of this modified ribonucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0206ef11402cfd290dde40eaaa813c78
https://doi.org/10.21203/rs.3.rs-2486374/v1
https://doi.org/10.21203/rs.3.rs-2486374/v1
Autor:
Joanna Sarzynska, Ryszard W. Adamiak, Agnieszka Korpeta, Marta Szachniuk, Mariusz Popenda, Tomasz Zok, Maciej Antczak
Publikováno v:
Nucleic Acids Research
Computational methods to predict RNA 3D structure have more and more practical applications in molecular biology and medicine. Therefore, it is crucial to intensify efforts to improve the accuracy and quality of predicted three-dimensional structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac3d8cbca37034aaaf57b76d20f51a2
http://europepmc.org/articles/PMC8464073
http://europepmc.org/articles/PMC8464073