Pulmonary Vascular Platform Models the Effects of Flow and Pressure on Endothelial Dysfunction in BMPR2 Associated Pulmonary Arterial Hypertension

Autor: Shannon Faley, Reid W. D’Amico, James West, Ha-na Shim, Leon M. Bellan, Vineet Agrawal, Joanna R. Prosser

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 9, p 2561 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 9

Endothelial dysfunction is a known consequence of bone morphogenetic protein type II receptor (BMPR2) mutations seen in pulmonary arterial hypertension (PAH). However, standard 2D cell culture models fail to mimic the mechanical environment seen in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c1f4d8aba5afeb007ce2302af3d698
http://www.mdpi.com/1422-0067/19/9/2561