Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joanna R. Ghali"'
Autor:
Joanna R Ghali, Kim M O'Sullivan, Peter J Eggenhuizen, Stephen R Holdsworth, A Richard Kitching
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123118 (2015)
Fms-like tyrosine kinase 3-ligand (FL) is a growth factor that may expand dendritic cell and regulatory T cell populations. We hypothesised that FL-induced regulatory T cells would protect mice from experimental rapidly progressive glomerulonephritis
Externí odkaz:
https://doaj.org/article/b82402d73a524bd3ba747305ffffd658
Autor:
Stephen R. Holdsworth, Kim M. O’Sullivan, Peter J. Eggenhuizen, Joanna R. Ghali, A. Richard Kitching
Publikováno v:
Nephron. 135:207-223
Background/Aims: Interleukin (IL)-17A and IL-17F are proinflammatory cytokines, which signal through a receptor complex consisting of IL-17RA and IL-17RC subunits. We sought to define the role of IL-17RA expression by leukocytes and stromal cells in
Publikováno v:
Immunology. 150:100-114
Regulatory T (Treg) cells are a suppressive CD4+ T‐cell subset. We generated induced Treg (iTreg) cells and explored their therapeutic potential in a murine model of rapidly progressive glomerulonephritis. Polyclonal naive CD4+ T cells were culture
Autor:
Qi Cao, Yiping Wang, Geoff Yu Zhang, David Harris, Dhanushka A. Hapudeniya, Andrew J. Sawyer, Ya Wang, Joanna R. Ghali, Jimmy Jianheng Zhou, Yuan Min Wang, Guoping Zheng, Stephen I. Alexander, Min Hu
Publikováno v:
Nephrology. 21:81-85
Regulatory T cells (Tregs) have been recognized as having a major role in maintaining peripheral tolerance and preventing and limiting autoimmune and chronic inflammatory diseases. Tregs derive from the thymus and also develop peripherally. In this r
Publikováno v:
Nephrology. 21:86-96
Regulatory T cells (Tregs) are CD4+ T cells that can suppress immune responses by effector T cells, B cells and innate immune cells. This review discusses the role that Tregs play in murine models of immune-mediated renal diseases and acute kidney in
Autor:
André Veillette, Steve Rockman, Sean Riminton, Alexander Karnowski, Matthew C. Cook, Cindy S. Ma, Carola G. Vinuesa, Stuart G. Tangye, Changqi Wang, Yew Ann Leong, Fabienne Mackay, Lei Zhu, Charles R. Mackay, Wei Wei, Zhanguo Li, Xin Jack Hu, Yan Ding, Kirsten Vandenberg, Joanna R. Ghali, Gabrielle T. Belz, Robert Brink, Di Yu, Jing He, Louis M Tsai, Nina Chevalier, Xiaolin Sun, Pamela L. Schwartzberg
Publikováno v:
Immunity. 39:770-781
Follicular B helper T (Tfh) cells support high affinity and long-term antibody responses. Here we found that within circulating CXCR5(+) CD4(+) T cells in humans and mice, the CCR7(lo)PD-1(hi) subset has a partial Tfh effector phenotype, whereas CCR7
Publikováno v:
Nephrology (Carlton, Vic.). 21(2)
Regulatory T cells (Tregs) are CD4+ T cells that can suppress immune responses by effector T cells, B cells and innate immune cells. This review discusses the role that Tregs play in murine models of immune-mediated renal diseases and acute kidney in
Autor:
Stephen R. Holdsworth, Maliha A. Alikhan, Mary B. Khouri, Dragana Odobasic, Poh Y. Gan, Joanna R. Ghali, Shaun A. Summers, Amy J. Chan, A. Richard Kitching, Joshua D. Ooi, Michael J. Hickey
Toll-like receptor 9 (TLR9) enhances proinflammatory responses, but whether it can act in a regulatory capacity remains to be established. In experimental murine AKI induced by cisplatin, Tlr9(-/-) mice developed enhanced renal injury and exhibited f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3778b1b91da0a5a191b9c71ac4c4b3d8
https://europepmc.org/articles/PMC4769185/
https://europepmc.org/articles/PMC4769185/
Autor:
Peter J. Eggenhuizen, Stephen R. Holdsworth, A. Richard Kitching, Joanna R. Ghali, Kim M. O’Sullivan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0123118 (2015)
PLoS ONE, Vol 10, Iss 4, p e0123118 (2015)
Fms-like tyrosine kinase 3-ligand (FL) is a growth factor that may expand dendritic cell and regulatory T cell populations. We hypothesised that FL-induced regulatory T cells would protect mice from experimental rapidly progressive glomerulonephritis
Publikováno v:
Current medicinal chemistry. 22(38)
T helper (Th) cells belong to the adaptive immune system and provide an effective and antigen-specific means of host protection. Th17 cells are a subset of Th cells, characterized by the production of the inflammatory cytokines interleukin (IL)-17A (