Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Joanna Przybyl"'
Autor:
Peng V. Wu, Matt Fish, Florette K. Hazard, Chunfang Zhu, Sujay Vennam, Hannah Walton, Dhananjay Wagh, John Coller, Joanna Przybyl, Maurizio Morri, Norma Neff, Robert B. West, Roel Nusse
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Cancers evolve not only through the acquisition and clonal transmission of somatic mutations but also by epigenetic mechanisms that modify cell phenotype. Here, we use histology-guided and spatial transcriptomics to characterize hepatoblasto
Externí odkaz:
https://doaj.org/article/2d94ec01e9d046b7b6d307f07deb9f1b
Autor:
Angela Tolwani, Magdalena Matusiak, Nam Bui, Erna Forgó, Sushama Varma, Lucia Baratto, Andrei Iagaru, Alexander J. Lazar, Matt van de Rijn, Joanna Przybyl
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Metabolic reprogramming of tumor cells and the increase of glucose uptake is one of the hallmarks of cancer. In order to identify metabolic pathways activated in leiomyosarcoma (LMS), we analyzed transcriptomic profiles of distinct subtypes
Externí odkaz:
https://doaj.org/article/fc3aae85255741adb708ed42e7403540
Autor:
Joanna Przybyl
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/63963ec17742492ba857c5cec6fbb073
Autor:
Joanna Przybyl, Lien Spans, Kristen Ganjoo, Nam Bui, David Mohler, Jeffrey Norton, George Poultsides, Maria Debiec-Rychter, Matt van de Rijn
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
High-level amplification of MDM2 and other genes in the 12q13–15 locus is a hallmark genetic feature of well-differentiated and dedifferentiated liposarcomas (WDLPS and DDLPS, respectively). Detection of this genomic aberration in plasma cell-free
Externí odkaz:
https://doaj.org/article/2d53d83c1672452da1da60f50e69f872
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-2 (2019)
Abstract A recent study on 15 patients with synovial sarcoma demonstrated very low prevalence of tumor-specific fusion transcripts in peripheral blood specimens. Our results in an independent cohort of 38 patients with synovial sarcoma support these
Externí odkaz:
https://doaj.org/article/8b8024e7e421463782002659a0bf4b67
Publikováno v:
Sarcoma, Vol 2012 (2012)
Synovial sarcoma (SS), an aggressive type of soft tissue tumor, occurs mostly in adolescents and young adults. The origin and molecular mechanism of the development of SS remain only partially known. Over 90% of SS cases are characterized by the t(X;
Externí odkaz:
https://doaj.org/article/1c7d796b98844c898a58ca885c12e065
Autor:
Mushriq Al-Jazrawe, Steven Xu, Raymond Poon, Qingxia Wei, Joanna Przybyl, Sushama Varma, Matt van de Rijn, Benjamin A. Alman
Publikováno v:
Cancer Research Communications. 3:697-708
The interaction between neoplastic and stromal cells within a tumor mass plays an important role in cancer biology. However, it is challenging to distinguish between tumor and stromal cells in mesenchymal tumors because lineage-specific cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bea65ef27f30583cb45558e40ff8788
https://doi.org/10.1158/2767-9764.crc-22-0403
https://doi.org/10.1158/2767-9764.crc-22-0403
Autor:
Benjamin Alman, Matt van de Rijn, Sushama Varma, Joanna Przybyl, Qingxia Wei, Raymond Poon, Steven Xu, Mushriq Al-Jazrawe
Densitometry of selected secreted proteome from mutant and non-mutant conditioned media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f94a09f2dcd7fcf32e431a8b04652f
https://doi.org/10.1158/2767-9764.22692860.v1
https://doi.org/10.1158/2767-9764.22692860.v1
Autor:
Benjamin Alman, Matt van de Rijn, Sushama Varma, Joanna Przybyl, Qingxia Wei, Raymond Poon, Steven Xu, Mushriq Al-Jazrawe
Cell surface profiling data of mutant and non-mutant desmoid tumor-derived colonies. Name of the sample indicates the mutation status (mutant (MUT) or wildtype (WT)) of the pooled colonies and the genotype (T41A or S45F) of the original primary sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4383942153f7ca326cba7c2ad0707089
https://doi.org/10.1158/2767-9764.22692827.v1
https://doi.org/10.1158/2767-9764.22692827.v1
Autor:
Benjamin Alman, Matt van de Rijn, Sushama Varma, Joanna Przybyl, Qingxia Wei, Raymond Poon, Steven Xu, Mushriq Al-Jazrawe
The interaction between neoplastic and stromal cells within a tumor mass plays an important role in cancer biology. However, it is challenging to distinguish between tumor and stromal cells in mesenchymal tumors because lineage-specific cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af021cd273e8187fad6f875a11114a6
https://doi.org/10.1158/2767-9764.c.6493286
https://doi.org/10.1158/2767-9764.c.6493286