Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Joanna Mikulak"'
Autor:
Sara Terzoli, Paolo Marzano, Valentina Cazzetta, Rocco Piazza, Inga Sandrock, Sarina Ravens, Likai Tan, Immo Prinz, Simone Balin, Michela Calvi, Anna Carletti, Assunta Cancellara, Nicolò Coianiz, Sara Franzese, Alessandro Frigo, Antonio Voza, Francesca Calcaterra, Clara Di Vito, Silvia Della Bella, Joanna Mikulak, Domenico Mavilio
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract γδ T cells provide rapid cellular immunity against pathogens. Here, we conducted matched single-cell RNA-sequencing and γδ-TCR-sequencing to delineate the molecular changes in γδ T cells during a longitudinal study following mRNA SARS-
Externí odkaz:
https://doaj.org/article/ed82b5055e4e4c92886da6d4f57cfc8d
Autor:
Paolo Marzano, Simone Balin, Sara Terzoli, Silvia Della Bella, Valentina Cazzetta, Rocco Piazza, Inga Sandrock, Sarina Ravens, Likai Tan, Immo Prinz, Francesca Calcaterra, Clara Di Vito, Assunta Cancellara, Michela Calvi, Anna Carletti, Sara Franzese, Alessandro Frigo, Ahmed Darwish, Antonio Voza, Joanna Mikulak, Domenico Mavilio
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHigher frequencies of mucosal-associated invariant T (MAIT) cells were associated with an increased adaptive response to mRNA BNT162b2 SARS-CoV-2 vaccine, however, the mechanistic insights into this relationship are unknown. In the presen
Externí odkaz:
https://doaj.org/article/df9be936320446999214947427c0b25e
Autor:
Claudia Carenza, Sara Franzese, Alessandra Castagna, Sara Terzoli, Matteo Simonelli, Pasquale Persico, Lorenzo Bello, Marco Conti Nibali, Federico Pessina, Paolo Kunderfranco, Clelia Peano, Simone Balin, Joanna Mikulak, Francesca Calcaterra, Raffaella Bonecchi, Benedetta Savino, Massimo Locati, Silvia Della Bella, Domenico Mavilio
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionAdult-type diffuse gliomas are malignant primary brain tumors characterized by very poor prognosis. Dendritic cells (DCs) are key in priming antitumor effector functions in cancer, but their role in gliomas remains poorly understood.Metho
Externí odkaz:
https://doaj.org/article/c5fce43a13f743ad9cbbc87709c2dfa9
Autor:
Alberto Mantovani, Barbara Franceschini, Domenico Mavilio, Cecilia Garlanda, Elena Bruni, Matteo Maria Cimino, Matteo Donadon, Roberta Carriero, Sara Terzoli, Rocco Piazza, Sarina Ravens, Immo Prinz, Valentina Cazzetta, Paolo Marzano, Paolo Kunderfranco, Clelia Peano, Cristiana Soldani, Federico Simone Colombo, Guido Torzilli, Joanna Mikulak
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background More than 50% of all patients with colorectal cancer (CRC) develop liver metastases (CLM), a clinical condition characterized by poor prognosis and lack of reliable prognostic markers. Vδ1 cells are a subset of tissue-resident gamma delta
Externí odkaz:
https://doaj.org/article/3aa6fb67f4ac490493471708b65d99fc
Autor:
Clara Di Vito, Francesca Calcaterra, Nicolò Coianiz, Sara Terzoli, Antonio Voza, Joanna Mikulak, Silvia Della Bella, Domenico Mavilio
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the control of viral infections in the absence of a prior antigen sensitization. Indeed, they display rapid effector functions against target cells with the
Externí odkaz:
https://doaj.org/article/51f4f372c6d541488a61d317e14f258e
Autor:
Elena Bruni, Valentina Cazzetta, Matteo Donadon, Matteo Cimino, Guido Torzilli, Gianmarco Spata, Gloria Leonardi, Francesco Dieli, Joanna Mikulak, Domenico Mavilio
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract Human (gamma delta) γδ T cells are unconventional innate-like lymphocytes displaying a broad array of anti-tumor activities with promising perspectives in cancer immunotherapy. In this context, Vδ2pos T cells represent the preferential ta
Externí odkaz:
https://doaj.org/article/90283269ab214e1b9f32c60c6481d39b
Autor:
Valentina Cazzetta, Elena Bruni, Sara Terzoli, Claudia Carenza, Sara Franzese, Rocco Piazza, Paolo Marzano, Matteo Donadon, Guido Torzilli, Matteo Cimino, Matteo Simonelli, Lorenzo Bello, Anna Villa, Likai Tan, Sarina Ravens, Immo Prinz, Domenico Supino, Federico S. Colombo, Enrico Lugli, Emanuela Marcenaro, Eric Vivier, Silvia Della Bella, Joanna Mikulak, Domenico Mavilio
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109871- (2021)
Summary: Human Vδ2 cells are innate-like γδ T effectors performing potent immune surveillance against tumors. The constitutive expression of NKG2A identifies a subset of Vδ2 T cells licensed with an intrinsic hyper-responsiveness against cancer.
Externí odkaz:
https://doaj.org/article/05645d72a7ba409498bd2a6ec58b97fb
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Natural Killer (NK) cells are innate lymphocytes playing pivotal roles in host defense and immune-surveillance. The homeostatic modulation of germ-line encoded/non-rearranged activating and inhibitory NK cell receptors (NKRs) determines the capabilit
Externí odkaz:
https://doaj.org/article/a1b999911da04e1eb98f348a69d8f81a
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The liver is considered a preferential tissue for NK cells residency. In humans, almost 50% of all intrahepatic lymphocytes are NK cells that are strongly imprinted in a liver-specific manner and show a broad spectrum of cellular heterogeneity. Hepat
Externí odkaz:
https://doaj.org/article/1b71df2752834932b46fa471ab88127d
Autor:
Marta Rusmini, Paola Griseri, Francesca Lantieri, Ivana Matera, Kelly L Hudspeth, Alessandra Roberto, Joanna Mikulak, Stefano Avanzini, Valentina Rossi, Girolamo Mattioli, Vincenzo Jasonni, Roberto Ravazzolo, William J Pavan, Alessio Pini-Prato, Isabella Ceccherini, Domenico Mavilio
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59066 (2013)
Hirschsprung disease (HSCR) is a rare congenital anomaly characterized by the absence of enteric ganglia in the distal intestinal tract. While classified as a multigenic disorder, the altered function of the RET tyrosine kinase receptor is responsibl
Externí odkaz:
https://doaj.org/article/b2f4adbada344814b0df37c59010517f