Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Joanna Mika"'
Autor:
Aleksandra Bober, Anna Piotrowska, Katarzyna Pawlik, Katarzyna Ciapała, Magdalena Maciuszek, Wioletta Makuch, Joanna Mika
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7410 (2024)
The ligands of chemokine receptors 2 and 5 (CCR2 and CCR5, respectively) are associated with the pathomechanism of neuropathic pain development, but their role in painful diabetic neuropathy remains unclear. Therefore, the aim of our study was to exa
Externí odkaz:
https://doaj.org/article/a7e81ade1c3848a99564ca7feb38cb70
Autor:
Agata Ciechanowska, Joanna Mika
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3788 (2024)
Despite significant progress in modern medicine and pharmacology, damage to the nervous system with various etiologies still poses a challenge to doctors and scientists. Injuries lead to neuroimmunological changes in the central nervous system (CNS),
Externí odkaz:
https://doaj.org/article/6465634fba394060af092fa2f73afaa7
Autor:
Katarzyna Ciapała, Joanna Mika
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1624 (2023)
Neuropathic pain is a complex and debilitating condition that affects millions of people worldwide. Unlike acute pain, which is short-term and starts suddenly in response to an injury, neuropathic pain arises from somatosensory nervous system damage
Externí odkaz:
https://doaj.org/article/2d4f759427fc42938813c706635ce268
Autor:
Agata Ciechanowska, Ewelina Rojewska, Anna Piotrowska, Justyna Barut, Katarzyna Pawlik, Katarzyna Ciapała, Grzegorz Kreiner, Joanna Mika
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recent studies have indicated the involvement of chemokine-C-motif ligand 1 (XCL1) in nociceptive transmission; however, the participation of its two receptors, canonical chemokine-C-motif receptor 1 (XCR1) and integrin alpha-9 (ITGA9), recently reco
Externí odkaz:
https://doaj.org/article/5724257977e54b9595b0dd126e1e3370
Autor:
Katarzyna Pawlik, Joanna Mika
Publikováno v:
Molecules, Vol 28, Iss 15, p 5766 (2023)
Neuropathic pain is a debilitating condition that affects millions of people worldwide. Numerous studies indicate that this type of pain is a chronic condition with a complex mechanism that tends to worsen over time, leading to a significant deterior
Externí odkaz:
https://doaj.org/article/aee396a730484548a7e40a85c064ae17
Autor:
Renata Zajączkowska, Katarzyna Pawlik, Katarzyna Ciapała, Anna Piotrowska, Agata Ciechanowska, Ewelina Rojewska, Magdalena Kocot-Kępska, Wioletta Makuch, Jerzy Wordliczek, Joanna Mika
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 1023 (2023)
Neuropathic pain is a chronic condition that significantly reduces the quality of life of many patients as a result of ineffective pain relief therapy. For that reason, looking for new analgesics remains an important issue. Mirogabalin is a new gabap
Externí odkaz:
https://doaj.org/article/86ad7ee8a43242a6bf44d5fd165d36a4
Autor:
Magdalena Kocot-Kępska, Katarzyna Pawlik, Katarzyna Ciapała, Wioletta Makuch, Renata Zajączkowska, Jan Dobrogowski, Anna Przeklasa-Muszyńska, Joanna Mika
Publikováno v:
Brain Sciences, Vol 13, Iss 6, p 858 (2023)
Neuropathic pain remains a clinical challenge due to its complex and not yet fully understood pathomechanism, which result in limited analgesic effectiveness of the management offered, particularly for patients with acute, refractory neuropathic pain
Externí odkaz:
https://doaj.org/article/6fe0c100b0c14522b725dcd49a5ad756
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9000 (2023)
Treatment of neuropathic pain remains a challenge for modern medicine due to the insufficiently understood molecular mechanisms of its development and maintenance. One of the most important cascades that modulate the nociceptive response is the famil
Externí odkaz:
https://doaj.org/article/e3a18a7cc1e74bbfa3aa1faabd53b8ee
Autor:
Marco Oggioni, Domenico Mercurio, Denise Minuta, Stefano Fumagalli, Katarzyna Popiolek-Barczyk, Marina Sironi, Agata Ciechanowska, Stefania Ippati, Daiana De Blasio, Carlo Perego, Joanna Mika, Cecilia Garlanda, Maria-Grazia De Simoni
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Long pentraxin PTX3, a pattern recognition molecule involved in innate immune responses, is upregulated by pro-inflammatory stimuli, contributors to secondary damage in traumatic brain injury (TBI). We analyzed PTX3 involvement in mice subje
Externí odkaz:
https://doaj.org/article/ab84c6e775b8498fa19cd39f64b559e4
Publikováno v:
Brain Sciences, Vol 13, Iss 4, p 579 (2023)
Neuropathic pain pathophysiology is not fully understood, but it was recently shown that MIP-1 family members (CCL3, CCL4, and CCL9) have strong pronociceptive properties. Our goal was to examine how pharmacological modulation of these chemokines and
Externí odkaz:
https://doaj.org/article/e2779acf3c31405d8bfb762cc2ab1fa5