Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Joanna Melia"'
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 2, Pp 260-270 (2024)
Background and Aims: Approximately 1 in 4 patients with ulcerative colitis experiences a severe exacerbation of disease requiring hospitalization, termed acute severe ulcerative colitis (ASUC). These episodes pose a major burden on patients with ulce
Externí odkaz:
https://doaj.org/article/436620bc82764d04a8d8e57005149d21
Autor:
Laxmi Sunuwar, Azra Frkatović, Sodbo Sharapov, Qinchuan Wang, Heather M. Neu, Xinqun Wu, Talin Haritunians, Fengyi Wan, Sarah Michel, Shaoguang Wu, Mark Donowitz, Dermot McGovern, Gordan Lauc, Cynthia Sears, Joanna Melia
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Externí odkaz:
https://doaj.org/article/c8a8d7250ef44726afdebb8c100fb512
Publikováno v:
bioRxiv
Manganese is a diet−derived micronutrient that is essential for critical cellular processes like redox homeostasis, protein glycosylation, and lipid and carbohydrate metabolism. Control of Mn availability, especially at the local site of infection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9a504e07851d4340658f5bf1ed5d28
https://europepmc.org/articles/PMC10055399/
https://europepmc.org/articles/PMC10055399/
Publikováno v:
Gastroenterology. 164:S57
Ulcerative colitis (UC) is a subtype of inflammatory bowel disease (IBD) that causes relapsing and remitting inflammation in the colon and rectum. Numerous treatment options are available for patients with UC including biologics and small molecule in
Autor:
Gala M Godoy Brewer, George Salem, Muhammad A Afzal, Berkeley N Limketkai, Zadid Haq, Maryam Tajamal, Joanna Melia, Mark Lazarev, Florin M Selaru, Alyssa M. Parian
Publikováno v:
BMJ Open Gastroenterology
BackgroundPerianal Crohn’s disease (pCD) is a debilitating complication affecting up to 30% of Crohn’s disease (CD) population, leading to increased morbidity, mortality and decreased quality of life. Despite the growing armamentarium of medicati
Autor:
Evangelos Tsipotis, Reezwana Chowdhury, Sharon Dudley-Brown, Mark Lazarev, Joanna Melia, Alyssa Parian, Florin M. Selaru, Huimin Yu, Brindusa Truta
Publikováno v:
Gastroenterology. 162:S-292
Autor:
Laura A. Maas, Berkeley N. Limketkai, Mark Lazarev, Joanna Melia, Florin M. Selaru, Alyssa M. Parian
Publikováno v:
Gastroenterology. 162:S-817
Autor:
George Salem, Cristian Hernandez-Rocha, Reezwana Chowdhury, Laura A. Maas, Simon J. Hong, James Conner, Mark S. Silverberg, Sharon Dudley-Brown, Joanna Melia, Alyssa Parian, Florin M. Selaru, Brindusa Truta, Huimin Yu, Mark Lazarev
Publikováno v:
Gastroenterology. 162:S-434
Autor:
Florin M. Selaru, George Salem, Reezwana Chowdhury, Gala Godoy Brewer, Alyssa Parian, Berkeley N. Limketkai, Joanna Melia, Katie A. Falloon, Mark Lazarev
Publikováno v:
Inflammatory bowel diseases. 27(9)
Background Patients with long-standing ulcerative colitis (UC) are at an increased risk of colorectal cancer. Risk stratification is important to identify patients who require more frequent endoscopic surveillance. Serrated epithelial change (SEC) fo
Autor:
Alyssa Parian, Sharon Dudley-Brown, Anthony J. Rizzo, Bashar Safar, Susan L. Gearhart, Mark Lazarev, Michael R. Marohn, Steven R. Brant, Weston Bettner, Jonathan E. Efron, Brindusa Truta, Elizabeth C. Wick, Maryam Kherad Pezhouh, Joanna Melia, Sandy H. Fang
Publikováno v:
Inflammatory Bowel Diseases
Background In inflammatory bowel disease (IBD), many scenarios call for fecal diversion, leaving behind defunctionalized bowel. The theoretical risk of colorectal cancer (CRC) in this segment is frequently cited as a reason for resection. To date, no