Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Joanna Maria Merchut-Maya"'
Publikováno v:
Cells, Vol 10, Iss 5, p 1068 (2021)
Lysosomes, acidic, membrane-bound organelles, are not only the core of the cellular recycling machinery, but they also serve as signaling hubs regulating various metabolic pathways. Lysosomes maintain energy homeostasis and provide pivotal substrates
Externí odkaz:
https://doaj.org/article/c304ecfcb58e460ab97c483ea8812261
Autor:
Dusana Majera, Zdenek Skrott, Katarina Chroma, Joanna Maria Merchut-Maya, Martin Mistrik, Jiri Bartek
Publikováno v:
Cells, Vol 9, Iss 2, p 469 (2020)
Research on repurposing the old alcohol-aversion drug disulfiram (DSF) for cancer treatment has identified inhibition of NPL4, an adaptor of the p97/VCP segregase essential for turnover of proteins involved in multiple pathways, as an unsuspected can
Externí odkaz:
https://doaj.org/article/723530eee941401d91ee45362c782d89
Human cytomegalovirus hijacks host stress response fueling replication stress and genome instability
Autor:
Joanna Maria Merchut-Maya, Jiri Bartek, Jirina Bartkova, Panagiotis Galanos, Mattia Russel Pantalone, MyungHee Lee, Huanhuan L. Cui, Patrick J. Shilling, Christian Beltoft Brøchner, Helle Broholm, Apolinar Maya-Mendoza, Cecilia Söderberg-Naucler
Publikováno v:
Cell Death & Differentiation. 29:1639-1653
Viral infections enhance cancer risk and threaten host genome integrity. Although human cytomegalovirus (HCMV) proteins have been detected in a wide spectrum of human malignancies and HCMV infections have been implicated in tumorigenesis, the underly
Autor:
Jiri Bartek, Jirina Bartkova, Christian B. Brøchner, Cecilia Söderberg-Nauclér, Apolinar Maya-Mendoza, Afsar Rahbar, Joanna Maria Merchut-Maya, Astrid Sehested, Olesja Fornara
Publikováno v:
Cell Cycle
Despite recent progress in research on brain tumors, including identification of cancer stem-like cells (CSCs), little is known about the interplay of stemness with the commonly observed infection by the human cytomegalovirus (HCMV) and the widesprea
Autor:
Jiri Bartek, Arnaldur Hall, Lin-Ping Wu, Robert Strauss, Joanna Maria Merchut-Maya, Seyed Moein Moghimi, Scott Maynard
Publikováno v:
Journal of Controlled Release. 309:158-172
Acquired resistance to the oncogenic BRAFE600 inhibitor vemurafenib is a major clinical challenge in the treatment of melanoma. Vemurafenib resistance is poorly understood; however, available evidence indicates that reprogrammed mitochondrial metabol
Autor:
Armando Bartolazzi, Marilena Raciti, Valentina Cianfanelli, Jiri Bartek, Rosalie C. Sears, Rikke Darling Rasmussen, Elena Papaleo, Jirina Bartkova, Guillermo Velasco, Miriam Di Marco, Robert E. Hynds, Francesco Russo, Petra Hamerlik, Salvatore Rizza, Emanuela Pupo, Cristiano De Stefanis, Franco Locatelli, Charles Swanton, Joanna Maria Merchut-Maya, Michele Pagano, Daniele Simoneschi, Søs Grønbæk Holdgaard, Letizia Lanzetti, Gergely Róna, Giacomo Milletti, Nélida Salvador, Giuseppe Filomeni, Luca Di Leo, Daniela De Zio, Francesca Nazio, Colin J. Daniel, Apolinar Maya-Mendoza, Alfie O’sullivan, Estibaliz Gabicagogeascoa, Angela Gallo, Francesco Cecconi, Silvia Campello, Matteo Bordi, Costanza Montagna, Yeon Tae Jeong, Valeriana Cesarini, David R. Pearce, Mar Lorente, Emiliano Maiani, Pasquale D’Acunzo, Marianna Carinci
Publikováno v:
Nature (Lond.) 592 (2021): 799–803. doi:10.1038/s41586-021-03422-5
info:cnr-pdr/source/autori:Maiani E.; Milletti G.; Nazio F.; Holdgaard S.G.; Bartkova J.; Rizza S.; Cianfanelli V.; Lorente M.; Simoneschi D.; Di Marco M.; D'Acunzo P.; Di Leo L.; Rasmussen R.; Montagna C.; Raciti M.; De Stefanis C.; Gabicagogeascoa E.; Rona G.; Salvador N.; Pupo E.; Merchut-Maya J.M.; Daniel C.J.; Carinci M.; Cesarini V.; O'sullivan A.; Jeong Y.-T.; Bordi M.; Russo F.; Campello S.; Gallo A.; Filomeni G.; Lanzetti L.; Sears R.C.; Hamerlik P.; Bartolazzi A.; Hynds R.E.; Pearce D.R.; Swanton C.; Pagano M.; Velasco G.; Papaleo E.; De Zio D.; Maya-Mendoza A.; Locatelli F.; Bartek J.; Cecconi F./titolo:AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity/doi:10.1038%2Fs41586-021-03422-5/rivista:Nature (Lond.)/anno:2021/pagina_da:799/pagina_a:803/intervallo_pagine:799–803/volume:592
Nature
Maiani, E, Milletti, G, Nazio, F, Holdgaard, S G, Bartkova, J, Rizza, S, Cianfanelli, V, Lorente, M, Simoneschi, D, Di Marco, M, D'Acunzo, P, Di Leo, L, Rasmussen, R, Montagna, C, Raciti, M, De Stefanis, C, Gabicagogeascoa, E, Rona, G, Salvador, N, Pupo, E, Merchut-Maya, J M, Daniel, C J, Carinci, M, Cesarini, V, O'sullivan, A, Jeong, Y-T, Bordi, M, Russo, F, Campello, S, Gallo, A, Filomeni, G, Lanzetti, L, Sears, R C, Hamerlik, P, Bartolazzi, A, Hynds, R E, Pearce, D R, Swanton, C, Pagano, M, Velasco, G, Papaleo, E, De Zio, D, Maya-Mendoza, A, Locatelli, F, Bartek, J & Cecconi, F 2021, ' AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity ', Nature, vol. 592, pp. 799-803 . https://doi.org/10.1038/s41586-021-03422-5
info:cnr-pdr/source/autori:Maiani E.; Milletti G.; Nazio F.; Holdgaard S.G.; Bartkova J.; Rizza S.; Cianfanelli V.; Lorente M.; Simoneschi D.; Di Marco M.; D'Acunzo P.; Di Leo L.; Rasmussen R.; Montagna C.; Raciti M.; De Stefanis C.; Gabicagogeascoa E.; Rona G.; Salvador N.; Pupo E.; Merchut-Maya J.M.; Daniel C.J.; Carinci M.; Cesarini V.; O'sullivan A.; Jeong Y.-T.; Bordi M.; Russo F.; Campello S.; Gallo A.; Filomeni G.; Lanzetti L.; Sears R.C.; Hamerlik P.; Bartolazzi A.; Hynds R.E.; Pearce D.R.; Swanton C.; Pagano M.; Velasco G.; Papaleo E.; De Zio D.; Maya-Mendoza A.; Locatelli F.; Bartek J.; Cecconi F./titolo:AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity/doi:10.1038%2Fs41586-021-03422-5/rivista:Nature (Lond.)/anno:2021/pagina_da:799/pagina_a:803/intervallo_pagine:799–803/volume:592
Nature
Maiani, E, Milletti, G, Nazio, F, Holdgaard, S G, Bartkova, J, Rizza, S, Cianfanelli, V, Lorente, M, Simoneschi, D, Di Marco, M, D'Acunzo, P, Di Leo, L, Rasmussen, R, Montagna, C, Raciti, M, De Stefanis, C, Gabicagogeascoa, E, Rona, G, Salvador, N, Pupo, E, Merchut-Maya, J M, Daniel, C J, Carinci, M, Cesarini, V, O'sullivan, A, Jeong, Y-T, Bordi, M, Russo, F, Campello, S, Gallo, A, Filomeni, G, Lanzetti, L, Sears, R C, Hamerlik, P, Bartolazzi, A, Hynds, R E, Pearce, D R, Swanton, C, Pagano, M, Velasco, G, Papaleo, E, De Zio, D, Maya-Mendoza, A, Locatelli, F, Bartek, J & Cecconi, F 2021, ' AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity ', Nature, vol. 592, pp. 799-803 . https://doi.org/10.1038/s41586-021-03422-5
Mammalian development, adult tissue homeostasis and the avoidance of severe diseases including cancer require a properly orchestrated cell cycle, as well as error-free genome maintenance. The key cell-fate decision to replicate the genome is controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb3a5f17bd536c3cceee8b07b588edc
https://hdl.handle.net/11590/423288
https://hdl.handle.net/11590/423288
Autor:
Katarina Chroma, Jiri Bartek, Dusana Majera, Martin Mistrik, Zdenek Skrott, Joanna Maria Merchut-Maya
Publikováno v:
Cells
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 469 (2020)
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 469 (2020)
Research on repurposing the old alcohol-aversion drug disulfiram (DSF) for cancer treatment has identified inhibition of NPL4, an adaptor of the p97/VCP segregase essential for turnover of proteins involved in multiple pathways, as an unsuspected can
Autor:
Joanna Maria Merchut-Maya, MyungHee Lee, Jiri Bartek, Pavel Moudry, Apolinar Maya-Mendoza, Robert Strauss
Publikováno v:
Nature. 559:279-284
Accurate replication of DNA requires stringent regulation to ensure genome integrity. In human cells, thousands of origins of replication are coordinately activated during S phase, and the velocity of replication forks is adjusted to fully replicate
Publikováno v:
DNA repair. 81
Replication of DNA is a fundamental biological process that ensures precise duplication of the genome and thus safeguards inheritance. Any errors occurring during this process must be repaired before the cell divides, by activating the DNA damage res
Autor:
Arnaldur, Hall, Scott, Maynard, Lin-Ping, Wu, Joanna Maria, Merchut-Maya, Robert, Strauss, Seyed Moein, Moghimi, Jiri, Bartek
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 309
Acquired resistance to the oncogenic BRAF