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pro vyhledávání: '"Joanna M.P. Melia"'
Genetic studies have informed on the genetic landscape of schizophrenia, and the next challenge is to link the genetic associations to mechanistic studies. A common single nucleotide polymorphism in the zinc and manganese transporter ZIP8 (rs13107325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8163aa9d384e9b2df76956e2149bde4d
https://doi.org/10.1101/2021.10.18.464839
https://doi.org/10.1101/2021.10.18.464839
Autor:
Cynthia L. Sears, Richard B. Thompson, Mark Donowitz, Dax Fu, Fengyi Wan, Ruxian Lin, Joanna M.P. Melia, Ramnik J. Xavier
Publikováno v:
Biochemical and Biophysical Research Communications. 515:325-331
Transition metals are required for intestinal homeostasis and provide essential nutrients for the resident microbiota. Abnormalities in metal homeostasis are common in Crohn's disease (CD), but remain poorly defined and causes appear multifactorial.
Autor:
Fengyi Wan, Sarah L. J. Michel, Shaoguang Wu, Joanna M.P. Melia, Talin Haritunians, Xinqun Wu, Cynthia L. Sears, Sodbo Zh Sharapov, Laxmi Sunuwar, Heather M. Neu, Azra Frkatović, Mark Donowitz, Gordan Lauc, Qinchuan Wang, Dermot P.B. McGovern
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight
JCI Insight
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Autor:
Laura C. Cappelli, Patrick M. Forde, William H. Sharfman, Karthik Suresh, Jiajia Zhang, Evan J. Lipson, Joanne Riemer, Jose M. Monroy-Trujillo, Lyle W. Ostrow, Julie R. Brahmer, Aanika Balaji, Jarushka Naidoo, Jenna Mammen, Joanna M.P. Melia, Amy K. Kim, Meghan Berkenstock, Inbal Sander
Publikováno v:
Journal of Clinical Oncology. 38:e15074-e15074
e15074 Background: Immune checkpoint inhibitors (ICIs) cause immune-related adverse events (irAEs) that may require multidisciplinary input. We developed an IR-Tox program consisting of an electronic irAE referral platform +/- in-person consultation,