Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joanna M. Wenda"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Substitution of lysine 27 with methionine in histone H3.3 (H3.3K27M) is a driver mutation of pediatric high-grade gliomas. Here the authors show that H3.3K27M-mediated alterations in H3K27me3 distribution result in ectopic DNA replication and cell cy
Externí odkaz:
https://doaj.org/article/15ff841362f0489ca570360241b3e7f6
Publikováno v:
Genome Research. 30:1740-1751
Histone H3.3 is a replication-independent variant of histone H3 with important roles in development, differentiation, and fertility. Here, we show that loss of H3.3 results in replication defects in Caenorhabditis elegans embryos at elevated temperat
Autor:
Karolina Łabędzka-Dmoch, Michal Rażew, Marta Gapińska, Jakub Piątkowski, Adam Kolondra, Hanna Salmonowicz, Joanna M. Wenda, Marcin Nowotny, Paweł Golik
Publikováno v:
RNA (New York, N.Y.). 28(5)
Pet127 is a mitochondrial protein found in multiple eukaryotic lineages, but absent from several taxa, including plants and animals. Distant homology suggests that it belongs to the divergent PD-(D/E)XK superfamily which includes various nucleases an
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Centromeres are chromosomal regions that serve as sites for kinetochore formation and microtubule attachment, processes that are essential for chromosome segregation during mitosis. Centromeres are almost universally defined by the histone variant CE
Centromeres are chromosomal regions that serve as sites for kinetochore formation and microtubule attachment, processes that are essential for chromosome segregation during mitosis. Centromeres are almost universally defined by the histone variant CE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12e7f9296798fde661a98a96625f90c
https://doi.org/10.1101/2021.07.01.450752
https://doi.org/10.1101/2021.07.01.450752
Autor:
Reinier F Prosée, Caroline Gabus, Isa Özdemir, Kamila Delaney, Monica Gotta, Florian A. Steiner, Françoise Schwager, Joanna M. Wenda
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 7, p e3000968 (2021)
PLoS biology, Vol. 19, No 7 (2021) P. e3000968
PLoS Biology, Vol 19, Iss 7, p e3000968 (2021)
PLoS biology, Vol. 19, No 7 (2021) P. e3000968
Centromere protein A (CENP-A) is a histone H3 variant that defines centromeric chromatin and is essential for centromere function. In most eukaryotes, CENP-A-containing chromatin is epigenetically maintained, and centromere identity is inherited from
Autor:
Kamila Delaney, Radha Raman Pandey, Florian A. Steiner, David Homolka, Ramesh S. Pillai, K.M. Chen, Mateusz Mendel, Cathrine Broberg Vågbø, Joanna M. Wenda
Publikováno v:
3125-3142.e25
Cell
Cell
Summary The N6-methyladenosine (m6A) RNA modification is used widely to alter the fate of mRNAs. Here we demonstrate that the C. elegans writer METT-10 (the ortholog of mouse METTL16) deposits an m6A mark on the 3′ splice site (AG) of the S-adenosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47b350471edf502b4abe27a847ae2cc
https://hdl.handle.net/11250/2982829
https://hdl.handle.net/11250/2982829
Autor:
Kamila Delaney, Caroline Gabus, Françoise Schwager, Joanna M. Wenda, Florian A. Steiner, Monica Gotta, Reinier F Prosée
Centromere protein A (CENP-A) is a histone H3 variant that defines centromeric chromatin and is essential for centromere function. In most eukaryotes CENP-A-containing chromatin is epigenetically maintained, and centromere identity is inherited from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b66a5471ca693d72ac6234ec316e574
https://doi.org/10.1101/2020.10.05.325985
https://doi.org/10.1101/2020.10.05.325985
Publikováno v:
Essays in Biochemistry
The aim of mitosis is to segregate duplicated chromosomes equally into daughter cells during cell division. Meiosis serves a similar purpose, but additionally separates homologous chromosomes to produce haploid gametes for sexual reproduction. Both m
Publikováno v:
Genome Res
Histone H3.3 is a replication-independent variant of histone H3 with important roles in development, differentiation, and fertility. Here, we show that loss of H3.3 results in replication defects in Caenorhabditis elegans embryos at elevated temperat