Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joanna M. Tarr"'
Publikováno v:
Journal of Ophthalmology, Vol 2010 (2010)
Objectives. Using apocynin (inhibitor of NADPH oxidase), and Mitoquinol 10 nitrate (MitoQ; mitochondrial-targeted antioxidant), we addressed the importance of mitochondria versus NADPH oxidase-derived ROS in glucose-induced apoptosis of pericytes. Me
Externí odkaz:
https://doaj.org/article/5599fdc763e14c41871bc5c80df8a6fe
Autor:
Edwin Bremer, Paul Eggleton, Marco de Bruyn, Jia Newcombe, Nicholas J. Gutowski, Alexandra C. Kendall, Joanna M. Tarr, Janet E. Holley, Wijnand Helfrich
Publikováno v:
Multiple Sclerosis and Related Disorders, 3(5), 650-658. ELSEVIER SCI LTD
Background: A subset of T-cells expresses the B-cell marker CD20 and in rheumatoid arthritis secretes Interleukin (IL)-17. IL-17 secreting T-cells (Th17) have also been implicated in the inflammatory response in the central nervous system in multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486348eb438628799b271ae2f51ec1a8
https://doi.org/10.1016/j.msard.2014.06.001
https://doi.org/10.1016/j.msard.2014.06.001
Autor:
Rakesh Chibber, Mohit Chopra, Eva M. Kohner, Ruhul Choudhury, Joanna M. Tarr, Thomas Phillip Ellis, Kirti Kaul
Publikováno v:
Current Diabetes Reviews. 9:146-160
Diabetic retinopathy (DR) is the leading cause of blindness amongst the working-age population, and diabetes accelerated cardiovascular disease (CVD) the commonest cause of death in diabetic patients. Although, there is evidence suggesting a close as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9d6be6b1271a06d211b498243378b9
https://doi.org/10.2174/157339913805076481
https://doi.org/10.2174/157339913805076481
Publikováno v:
Cellular Signalling. 24:873-878
Increasing evidence suggests that chronic, sub-clinical inflammation plays an important role in the pathogenesis of diabetic retinopathy. We have established the potential role of the inflammatory enzyme, core 2 β-1, 6-N-acetylglucosaminyltransferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97fc69de9ae70671edfa03aabb2e1f77
https://doi.org/10.1016/j.cellsig.2011.12.003
https://doi.org/10.1016/j.cellsig.2011.12.003
Autor:
Robert Morse, Philip J. Young, Joanna M. Tarr, Paul Eggleton, Debra J. Shaw, Steven Johnson, Paul G. Winyard, Peter G. Petrov, Richard C Haigh
Publikováno v:
Journal of Molecular Biology. 401:799-812
Calreticulin (CRT) is an endoplasmic reticulum (ER) chaperone responsible for glycoprotein folding and Ca 2+ homeostasis. CRT also has extracellular functions, e.g. tumor and apoptotic cell recognition and wound healing, but the mechanism of CRT extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e83cb6eb8539a80bea690dbb4aabd9
https://doi.org/10.1016/j.jmb.2010.06.064
https://doi.org/10.1016/j.jmb.2010.06.064
Autor:
Kim M. Gooding, Richard C Haigh, Matthew Whiteman, Angela C. Shore, Paul G. Winyard, Joanna M. Tarr
Publikováno v:
Annals of the New York Academy of Sciences. 1203:146-150
Blood concentrations of hydrogen sulfide (H(2)S) are markedly elevated in several animal models of inflammation. Pharmacological inhibition of H(2)S synthesis reduces inflammation and swelling, suggesting that H(2)S is a potential inflammatory mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30fb4955de2c0e66c6204cac889071d0
https://doi.org/10.1111/j.1749-6632.2010.05556.x
https://doi.org/10.1111/j.1749-6632.2010.05556.x
Autor:
Naila Rabbani, Attia Anwar, Usman Ahmed, Matthew L. Costa, Nicola D Mackay, Paul G. Winyard, Paul J. Thornalley, Andrew Filer, Richard S. Savage, Richard C Haigh, Karim Raza, Joanna M. Tarr, Richard A. Watts
Publikováno v:
Scientific Reports
There is currently no biochemical test for detection of early-stage osteoarthritis (eOA). Tests for early-stage rheumatoid arthritis (eRA) such as rheumatoid factor (RF) and anti–cyclic citrullinated peptide (CCP) antibodies require refinement to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c52943dcc23ecb7751c28b816244775
https://doi.org/10.1038/srep09259
https://doi.org/10.1038/srep09259
Publikováno v:
ResearcherID
Nitric oxide (NO) is a small, highly reactive, diffusible free radical which has been implicated in many physiological and pathophysiological processes. It has either pro-apoptotic or anti-apoptotic effects on cells, depending upon a host of factors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6652a6252d958073c76496999996c7
https://doi.org/10.2174/138161206779010477
https://doi.org/10.2174/138161206779010477
Publikováno v:
Advances in experimental medicine and biology. 771
With the incidence, and prevalence of diabetes mellitus increasing worldwide, diabetic retinopathy is expected to reach epidemic proportions. The aim of this chapter is to introduce diabetic retinopathy, a leading cause of blindness in people of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72833061f52c51fa5150ac1f9b236769
https://pubmed.ncbi.nlm.nih.gov/23393674
https://pubmed.ncbi.nlm.nih.gov/23393674
Publikováno v:
Advances in experimental medicine and biology. 771
The chronic metabolic disorder diabetes mellitus is a fast-growing global problem with huge social, health, and economic consequences. It is estimated that in 2010 there were globally 285 million people (approximately 6.4% of the adult population) su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ca157a2a557493d0a56abd2924cf7ae
https://pubmed.ncbi.nlm.nih.gov/23393665
https://pubmed.ncbi.nlm.nih.gov/23393665