Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Joanna M, Williams"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract Current clinical tests for Parkinson’s disease (PD) provide insufficient diagnostic accuracy leading to an urgent need for improved diagnostic biomarkers. As microRNAs (miRNAs) are promising biomarkers of various diseases, including PD, th
Externí odkaz:
https://doaj.org/article/e4fb0f1b1c3943fb9b83815221a84ac2
Autor:
Nikita Potemkin, Sophie M. F. Cawood, Jackson Treece, Diane Guévremont, Christy J. Rand, Catriona McLean, Jo-Ann L. Stanton, Joanna M. Williams
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract RNA sequencing offers unprecedented access to the transcriptome. Key to this is the identification and quantification of many different species of RNA from the same sample at the same time. In this study we describe a novel protocol for simu
Externí odkaz:
https://doaj.org/article/a7d7921e30b34c38876a6b356d48fd25
Autor:
Aimee J. Chu, Joanna M. Williams
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Astrocytes actively regulate numerous cell types both within and outside of the central nervous system in health and disease. Indeed, astrocyte morphology, gene expression and function, alongside the content of astrocyte-derived extracellular vesicle
Externí odkaz:
https://doaj.org/article/3f576707d968447fbf2df01aefe3877b
Autor:
Rhys W. Livingstone, Megan K. Elder, Anurag Singh, Courteney M. Westlake, Warren P. Tate, Wickliffe C. Abraham, Joanna M. Williams
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Regulation of AMPA receptor expression by neuronal activity and neuromodulators is critical to the expression of both long-term potentiation (LTP) and memory. In particular, Ca2+-permeable AMPARs (CP-AMPAR) play a unique role in these processes due t
Externí odkaz:
https://doaj.org/article/9290877e3a9240328cd488775be4af9a
Autor:
Brigid Ryan, Ashleigh O’Mara Baker, Christina Ilse, Kiri L. Brickell, Hannah M. Kersten, Joanna M. Williams, Donna Rose Addis, Lynette J. Tippett, Maurice A. Curtis
Publikováno v:
Journal of the Royal Society of New Zealand. 53:511-531
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f6bfe454d953c31d7b361d7e1a22277
https://doi.org/10.1080/03036758.2022.2101483
https://doi.org/10.1080/03036758.2022.2101483
Autor:
Rhys W. Livingstone, Megan K. Elder, Maya C. Barrett, Courteney M. Westlake, Katie Peppercorn, Warren P. Tate, Wickliffe C. Abraham, Joanna M. Williams
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Secreted amyloid precursor protein-α (sAPPα) is a neuroprotective and memory-enhancing molecule, however, the mechanisms through which sAPPα promotes these effects are not well understood. Recently, we have shown that sAPPα enhances cell-surface
Externí odkaz:
https://doaj.org/article/d8621d86ccc64b138cfd845ca9e51ebf
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
How memories are maintained, and how memories are lost during aging or disease, are intensely investigated issues. Arguably, the reigning theory is that synaptic modifications allow for the formation of engrams during learning, and sustaining engrams
Externí odkaz:
https://doaj.org/article/2a6f4f7f41fd482c9d15ec279c588072
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170407 (2017)
Translation of synaptic mRNA contributes to alterations in the proteome necessary to consolidate long-term potentiation (LTP), a model of memory processes. Yet, how this process is controlled is not fully resolved. MicroRNAs are non-coding RNAs that
Externí odkaz:
https://doaj.org/article/e371dc051417451fab0cdd7cac7b483f
Autor:
Megan K. Elder, Aline Loehfelm, Alexander Tups, Peter P. Jones, Joanna M. Williams, Alisa Boucsein
Publikováno v:
The FASEB Journal. 34:4635-4652
The importance of fatty acids (FAs) for healthy brain development and function has become more evident in the past decades. However, most studies focus on the hypothalamus as an important FA-sensing brain region involved in energy homeostasis. Less w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629f906be82bbb203eb032d0c518a62c
https://doi.org/10.1096/fj.201902517r
https://doi.org/10.1096/fj.201902517r
Autor:
Nikita Potemkin, Sophie M. F. Cawood, Jackson Treece, Diane Guévremont, Christy J. Rand, Catriona McLean, Jo-Ann L. Stanton, Joanna M. Williams
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
RNA sequencing offers unprecedented access to the transcriptome. Key to this is the identification and quantification of many different species of RNA from the same sample at the same time. In this study we describe a novel protocol for simultaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e320b6bf5aa3dba9bd4e7bc3543e545
https://pubmed.ncbi.nlm.nih.gov/35022475
https://pubmed.ncbi.nlm.nih.gov/35022475