Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Joanna L. Parish"'
Autor:
Janne J. M. van Schie, Atiq Faramarz, Jesper A. Balk, Grant S. Stewart, Erika Cantelli, Anneke B. Oostra, Martin A. Rooimans, Joanna L. Parish, Cynthia de Almeida Estéves, Katja Dumic, Ingeborg Barisic, Karin E. M. Diderich, Marjon A. van Slegtenhorst, Mohammad Mahtab, Francesca M. Pisani, Hein te Riele, Najim Ameziane, Rob M. F. Wolthuis, Job de Lange
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
WABS patient derived cells display loss of sister chromatid cohesion. Here the authors by analyzing WABS patient derived cells, reveal a role of the DDX11 helicase in resolving G-Quadruplex structures to support sister chromatid cohesion.
Externí odkaz:
https://doaj.org/article/d1dd653aad8b4232927aa9fceeb46e31
Autor:
Jack Ferguson, Karen Campos-León, Ieisha Pentland, Joanne D. Stockton, Thomas Günther, Andrew D. Beggs, Adam Grundhoff, Sally Roberts, Boris Noyvert, Joanna L. Parish
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11 (2021)
The ubiquitous host protein, CCCTC-binding factor (CTCF), is an essential regulator of cellular transcription and functions to maintain epigenetic boundaries, stabilise chromatin loops and regulate splicing of alternative exons. We have previously de
Externí odkaz:
https://doaj.org/article/e712c91edf7a40829e4e81e8544306f3
From infection to cancer: how DNA tumour viruses alter host cell central carbon and lipid metabolism
Autor:
Kamini L. Magon, Joanna L. Parish
Publikováno v:
Open Biology, Vol 11, Iss 3 (2021)
Infections cause 13% of all cancers globally, and DNA tumour viruses account for almost 60% of these cancers. All viruses are obligate intracellular parasites and hijack host cell functions to replicate and complete their life cycles to produce proge
Externí odkaz:
https://doaj.org/article/499dfe5d61de4690b5038c66ef6bd844
Autor:
Ieisha Pentland, Joanna L. Parish
Publikováno v:
Viruses, Vol 7, Iss 7, Pp 3574-3585 (2015)
All viruses target host cell factors for successful life cycle completion. Transcriptional control of DNA viruses by host cell factors is important in the temporal and spatial regulation of virus gene expression. Many of these factors are recruited t
Externí odkaz:
https://doaj.org/article/81ad66d7f9f34b4c941bec2af68493b8
Publikováno v:
Viruses, Vol 6, Iss 7, Pp 2762-2777 (2014)
Cervical cancer is the third most common cause of cancer-related death in women worldwide. Infection with high-risk human papillomavirus (HPV) is established as the cause of cervical carcinoma, therefore, high risk HPV detection may have prognostic s
Externí odkaz:
https://doaj.org/article/808330e819b149228fe78803485cefa9
Autor:
Hannah J. Gleneadie, Alfredo A. Molinolo, Deena M.A. Gendoo, Yao Jiang, Amy H. Baker, Jennifer L. Bryant, Sally Roberts, Paloma Garcia, Megan Burley, Joanna L Parish, J. Silvio Gutkind, Hisham Mehanna, Ben A. Scheven, Malgorzata Wiench, Nikolaos Batis, Farhat L. Khanim, Paul R. Cooper, Samuel J.H. Clokie
Publikováno v:
Cancer Letters
The DNA demethylating agent 5-aza-2′-deoxycytidine (DAC, decitabine) has anti-cancer therapeutic potential, but its clinical efficacy is hindered by DNA damage-related side effects and its use in solid tumours is debated. Here we describe how parac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe4cd8568248d99b4bf1ab3a36cfd2a
https://doi.org/10.1016/j.canlet.2020.12.029
https://doi.org/10.1016/j.canlet.2020.12.029
Publikováno v:
Current opinion in virology. 55
Persistent virus infections are achieved when the intricate balance of virus replication, host-cell division and successful immune evasion is met. The genomes of persistent DNA viruses are either maintained as extrachromosomal episomes or can integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf1c480d340a598559ec3ceb063d2a3
https://pubmed.ncbi.nlm.nih.gov/35998396
https://pubmed.ncbi.nlm.nih.gov/35998396
Publikováno v:
Seminars in Immunopathology
Human papillomaviruses (HPV) are a large family of viruses which contain a circular, double-stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by the recruitment of cellular histones which are subject to host cell–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3964666163c50fe5654170313acefa0
https://doi.org/10.1007/s00281-019-00773-0
https://doi.org/10.1007/s00281-019-00773-0
Autor:
Karen Campos-León, Joanne D. Stockton, Andrew D Beggs, Joanna L Parish, Boris Noyvert, Ieisha Pentland, Sally Roberts, Thomas Günther, Jack Ferguson
The ubiquitous host protein, CCCTC-binding factor (CTCF), is an essential regulator of cellular transcription and functions to maintain epigenetic boundaries, stabilise chromatin loops and regulate splicing of alternative exons. We have previously de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::929fc92b4a1d7214fbe44fde1c793d0a
https://doi.org/10.1101/2021.04.30.442078
https://doi.org/10.1101/2021.04.30.442078
Human papillomavirus 16 (HPV16) is a high-risk alphapapillomavirus that is associated with cancers of mucosal epithelia. The virus genome exists in cells as an episome but can integrate and overexpress the E6 and E7 viral oncogenes. In related high-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f22b9cca3d04a1e00c1177c4919f15
https://doi.org/10.1101/2021.02.18.431881
https://doi.org/10.1101/2021.02.18.431881