Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Joanna L. Parish"'
Autor:
Janne J. M. van Schie, Atiq Faramarz, Jesper A. Balk, Grant S. Stewart, Erika Cantelli, Anneke B. Oostra, Martin A. Rooimans, Joanna L. Parish, Cynthia de Almeida Estéves, Katja Dumic, Ingeborg Barisic, Karin E. M. Diderich, Marjon A. van Slegtenhorst, Mohammad Mahtab, Francesca M. Pisani, Hein te Riele, Najim Ameziane, Rob M. F. Wolthuis, Job de Lange
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
WABS patient derived cells display loss of sister chromatid cohesion. Here the authors by analyzing WABS patient derived cells, reveal a role of the DDX11 helicase in resolving G-Quadruplex structures to support sister chromatid cohesion.
Externí odkaz:
https://doaj.org/article/d1dd653aad8b4232927aa9fceeb46e31
Autor:
Jack Ferguson, Karen Campos-León, Ieisha Pentland, Joanne D. Stockton, Thomas Günther, Andrew D. Beggs, Adam Grundhoff, Sally Roberts, Boris Noyvert, Joanna L. Parish
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11 (2021)
The ubiquitous host protein, CCCTC-binding factor (CTCF), is an essential regulator of cellular transcription and functions to maintain epigenetic boundaries, stabilise chromatin loops and regulate splicing of alternative exons. We have previously de
Externí odkaz:
https://doaj.org/article/e712c91edf7a40829e4e81e8544306f3
From infection to cancer: how DNA tumour viruses alter host cell central carbon and lipid metabolism
Autor:
Kamini L. Magon, Joanna L. Parish
Publikováno v:
Open Biology, Vol 11, Iss 3 (2021)
Infections cause 13% of all cancers globally, and DNA tumour viruses account for almost 60% of these cancers. All viruses are obligate intracellular parasites and hijack host cell functions to replicate and complete their life cycles to produce proge
Externí odkaz:
https://doaj.org/article/499dfe5d61de4690b5038c66ef6bd844
Autor:
Ieisha Pentland, Karen Campos-León, Marius Cotic, Kelli-Jo Davies, C David Wood, Ian J Groves, Megan Burley, Nicholas Coleman, Joanne D Stockton, Boris Noyvert, Andrew D Beggs, Michelle J West, Sally Roberts, Joanna L Parish
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e2005752 (2018)
The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted. Upon epithelial differentiation, E6/E7 transcription is increased t
Externí odkaz:
https://doaj.org/article/2b634e44faf441ed83f18dab7b93bedd
Autor:
Ethan L Morgan, Christopher W Wasson, Lucy Hanson, David Kealy, Ieisha Pentland, Victoria McGuire, Cinzia Scarpini, Nicholas Coleman, J Simon C Arthur, Joanna L Parish, Sally Roberts, Andrew Macdonald
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006975 (2018)
Human papillomaviruses (HPV) activate a number of host factors to control their differentiation-dependent life cycles. The transcription factor signal transducer and activator of transcription (STAT)-3 is important for cell cycle progression and cell
Externí odkaz:
https://doaj.org/article/e238124870e24d9a84f1a35422dae093
Autor:
Nicole V Anayannis, Nicolas F Schlecht, Miriam Ben-Dayan, Richard V Smith, Thomas J Belbin, Thomas J Ow, Duk M Blakaj, Robert D Burk, Sarah M Leonard, Ciaran B Woodman, Joanna L Parish, Michael B Prystowsky
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191581 (2018)
To assess the relationship of E2 gene disruption with viral gene expression and clinical outcome in human papillomavirus (HPV) positive head and neck squamous cell carcinoma, we evaluated 31 oropharyngeal and 17 non-oropharyngeal HPV16 positive carci
Externí odkaz:
https://doaj.org/article/4e623ed60d2d4785a84aca7798b15598
Autor:
Ieisha Pentland, Joanna L. Parish
Publikováno v:
Viruses, Vol 7, Iss 7, Pp 3574-3585 (2015)
All viruses target host cell factors for successful life cycle completion. Transcriptional control of DNA viruses by host cell factors is important in the temporal and spatial regulation of virus gene expression. Many of these factors are recruited t
Externí odkaz:
https://doaj.org/article/81ad66d7f9f34b4c941bec2af68493b8
Publikováno v:
Viruses, Vol 6, Iss 7, Pp 2762-2777 (2014)
Cervical cancer is the third most common cause of cancer-related death in women worldwide. Infection with high-risk human papillomavirus (HPV) is established as the cause of cervical carcinoma, therefore, high risk HPV detection may have prognostic s
Externí odkaz:
https://doaj.org/article/808330e819b149228fe78803485cefa9
Autor:
Hannah J. Gleneadie, Alfredo A. Molinolo, Deena M.A. Gendoo, Yao Jiang, Amy H. Baker, Jennifer L. Bryant, Sally Roberts, Paloma Garcia, Megan Burley, Joanna L Parish, J. Silvio Gutkind, Hisham Mehanna, Ben A. Scheven, Malgorzata Wiench, Nikolaos Batis, Farhat L. Khanim, Paul R. Cooper, Samuel J.H. Clokie
Publikováno v:
Cancer Letters
The DNA demethylating agent 5-aza-2′-deoxycytidine (DAC, decitabine) has anti-cancer therapeutic potential, but its clinical efficacy is hindered by DNA damage-related side effects and its use in solid tumours is debated. Here we describe how parac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe4cd8568248d99b4bf1ab3a36cfd2a
https://doi.org/10.1016/j.canlet.2020.12.029
https://doi.org/10.1016/j.canlet.2020.12.029
Publikováno v:
Current opinion in virology. 55
Persistent virus infections are achieved when the intricate balance of virus replication, host-cell division and successful immune evasion is met. The genomes of persistent DNA viruses are either maintained as extrachromosomal episomes or can integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf1c480d340a598559ec3ceb063d2a3
https://pubmed.ncbi.nlm.nih.gov/35998396
https://pubmed.ncbi.nlm.nih.gov/35998396