Výsledky vyhledávání - "Joanna L Brown"

Respiratory specialists working in different ways: development of a GP hotline and respiratory support service during the COVID-19 pandemic

Autor: Mohini Parmar, Anna Bokobza, Yasmin Razak, Sarah L. Elkin, V Mak, Loong-Yuan Han, Ernie Wong, Toby Hyde, Kartik Kumar, Joanna L Brown, Katherine Groom, R K Coker

Publikováno v: e92
e88
Future Healthc J

Integration of primary and secondary care for the management of respiratory disease is a long-held ambition. Here, we describe how respiratory specialists at a large NHS trust, working with primary care clinicians in the area, set up a GP hotline and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f2a3f091b28e713461c33e0d8cb918
http://hdl.handle.net/10044/1/104159

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Proinflammatory doses of diesel exhaust in healthy subjects fail to elicit equivalent or augmented airway inflammation in subjects with asthma

Autor: Thomas Sandström, Nirina Larsson, Ragnberth Helleday, Sean T Duggan, Annelie F. Behndig, Susan J. Wilson, Ian Mudway, Joanna L Brown, Anders Blomberg, Frank J. Kelly, Nikolai Stenfors, Rosamund Dove

Publikováno v: Thorax. 66:12-19

Exposure to traffic-derived air pollutants, particularly diesel emissions, has been associated with adverse health effects, predominantly in individuals with pre-existing respiratory disease. Here the hypothesis that this heightened sensitivity refle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56354dc4be446893e0a7fa0e43b46946
https://doi.org/10.1136/thx.2010.140053

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Effects of controlled diesel exhaust exposure on apoptosis and proliferation markers in bronchial epithelium – an in vivo bronchoscopy study on asthmatics, rhinitics and healthy subjects

Autor: Ian Mudway, Susan J. Wilson, Thomas Sandström, Nikolai Stenfors, Frank J. Kelly, Anthony J. Frew, Joanna L Brown, Annelie F. Behndig, Laura Whitmarsh, Karthika Shanmuganathan

Publikováno v: BMC Pulmonary Medicine

BackgroundEpidemiological evidence demonstrates that exposure to traffic-derived pollution worsens respiratory symptoms in asthmatics, but controlled human exposure studies have failed to provide a mechanism for this effect. Here we investigated whet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5619ac2c482d81ed7156ca7e28278c1
https://eprints.soton.ac.uk/384294/

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Airway inflammatory responses to diesel exhaust in allergic rhinitics

Autor: Nikolai Stenfors, Nirina Larsson, Jamshid Pourazar, Joanna L Brown, Susan J. Wilson, Ian Mudway, Annelie F. Behndig

Publikováno v: Inhalation toxicology. 25(3)

Proximity to traffic, particularly to diesel-powered vehicles, has been associated with inducing and enhancing allergies. To investigate the basis for this association, we performed controlled exposures of allergic rhinitics to diesel exhaust (DE) at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c792ba2b54f85478869bc260c50084
https://pubmed.ncbi.nlm.nih.gov/23421487

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Lower airways inflammation in allergic rhinitics: a comparison with asthmatics and normal controls

Autor: Thomas Sandström, Jamshid Pourazar, A. J. Frew, Susan J. Wilson, Bulent Enis Sekerel, Joanna L Brown, Anders Blomberg, Annelie F. Behndig, Frank J. Kelly

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 37(5)

Allergic rhinitis (AR) and asthma represent a continuum of atopic disease. AR is believed to pre-dispose an individual to asthma. Compared with asthmatics and normal controls, the inflammatory response in the lower airways of rhinitics is not fully e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0056ac439d55f293a886dedd7d0dcbd
https://pubmed.ncbi.nlm.nih.gov/17456216

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Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans

Autor: Thomas Sandström, Nikolai Stenfors, Ian Mudway, Sean T Duggan, Christoffer Boman, Ragnberth Helleday, Susan J. Wilson, Anthony J. Frew, Annelie F. Behndig, Frank J. Kelly, Flemming R. Cassee, Joanna L Brown, Anders Blomberg

Publikováno v: The European respiratory journal. 27(2)

Pulmonary cells exposed to diesel exhaust (DE) particles in vitro respond in a hierarchical fashion with protective antioxidant responses predominating at low doses and inflammation and injury only occurring at higher concentrations. In the present s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d276ec1e4ff2f05fae10774cf19b70d
https://pubmed.ncbi.nlm.nih.gov/16452593

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