Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Joanna Kopec"'
Autor:
Sabrina Digiovanni, Martina Lorenzati, Olga Teresa Bianciotto, Martina Godel, Simona Fontana, Muhlis Akman, Costanzo Costamagna, Pierre-Olivier Couraud, Annalisa Buffo, Joanna Kopecka, Chiara Riganti, Iris Chiara Salaroglio
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background Glioblastoma multiforme (GBM) is an aggressive tumor, difficult to treat pharmacologically because of the blood-brain barrier (BBB), which is rich in ATP-binding cassette (ABC) transporters and tight junction (TJ) proteins. The BB
Externí odkaz:
https://doaj.org/article/2b2c812198ba450381fa3d549a94c212
Autor:
Muhlis Akman, Ciro Monteleone, Gabriella Doronzo, Martina Godel, Francesca Napoli, Alessandra Merlini, Virginia Campani, Valeria Nele, Elisa Balmas, Tatiana Chontorotzea, Simona Fontana, Sabrina Digiovanni, Francesca Alice Barbu, Elena Astanina, Niloufar Jafari, Iris Chiara Salaroglio, Joanna Kopecka, Giuseppe De Rosa, Thomas Mohr, Alessandro Bertero, Luisella Righi, Silvia Novello, Giorgio Vittorio Scagliotti, Federico Bussolino, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background In non-small cell lung cancer (NSCLC) the efficacy of chemo-immunotherapy is affected by the high expression of drug efflux transporters as ABCC1 and by the low expression of ABCA1, mediating the isopentenyl pyrophosphate (IPP)-de
Externí odkaz:
https://doaj.org/article/4a6851a8a8824044acb7cc89ddb408bf
Autor:
Claudia Kalla, German Ott, Francesca Finotello, Karolina Niewola-Staszkowska, Giusy Di Conza, Michael Lahn, Lars van der Veen, Julia Schüler, Roger Falkenstern-Ge, Joanna Kopecka, Chiara Riganti
Publikováno v:
Translational Oncology, Vol 43, Iss , Pp 101857- (2024)
Targeting aberrantly expressed kinases in malignant pleural mesothelioma (MPM) is a promising therapeutic strategy. We here investigated the effect of the novel and highly selective Phosphoinositide 3-kinase delta (PI3K-δ) inhibitor roginolisib (IOA
Externí odkaz:
https://doaj.org/article/29e97e2677864d378073466d49ffbb29
Autor:
Giorgia Centonze, Dora Natalini, Silvia Grasso, Alessandro Morellato, Vincenzo Salemme, Alessio Piccolantonio, Giacomo D’Attanasio, Aurora Savino, Olga Teresa Bianciotto, Matteo Fragomeni, Andrea Scavuzzo, Matteo Poncina, Francesca Nigrelli, Mario De Gregorio, Valeria Poli, Pietro Arina, Daniela Taverna, Joanna Kopecka, Sirio Dupont, Emilia Turco, Chiara Riganti, Paola Defilippi
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-16 (2023)
Abstract p140Cap is an adaptor protein involved in assembling multi-protein complexes regulating several cellular processes. p140Cap acts as a tumor suppressor in breast cancer (BC) and neuroblastoma patients, where its expression correlates with a b
Externí odkaz:
https://doaj.org/article/9b85e2507048469f836b2d800e0a4611
Autor:
Joanna Kopeć
Publikováno v:
Acta Universitatis Lodziensis: Folia Litteraria Romanica, Vol 18, Pp 147-164 (2023)
Cette contribution est centrée sur l’enseignement-apprentissage du lexique émotionnel lié aux concepts de solitude et de silence, en vue du développement de la compétence rédactionnelle en français langue étrangère au niveau avancé (B2).
Externí odkaz:
https://doaj.org/article/36e442ecb2904557907c520bffb0f451
Autor:
Muhlis Akman, Ciro Monteleone, Gabriella Doronzo, Martina Godel, Francesca Napoli, Alessandra Merlini, Virginia Campani, Valeria Nele, Elisa Balmas, Tatiana Chontorotzea, Simona Fontana, Sabrina Digiovanni, Francesca Alice Barbu, Elena Astanina, Niloufar Jafari, Iris Chiara Salaroglio, Joanna Kopecka, Giuseppe De Rosa, Thomas Mohr, Alessandro Bertero, Luisella Righi, Silvia Novello, Giorgio Vittorio Scagliotti, Federico Bussolino, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/695ef33a539a4a9296cf6230050b6b60
Autor:
Iris C. Salaroglio, Dimas Carolina Belisario, Muhlis Akman, Sofia La Vecchia, Martina Godel, Dario Pasquale Anobile, Giacomo Ortone, Sabrina Digiovanni, Simona Fontana, Costanzo Costamagna, Menachem Rubinstein, Joanna Kopecka, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-24 (2022)
Abstract Background Solid tumors subjected to intermittent hypoxia are characterized by resistance to chemotherapy and immune-killing by effector T-lymphocytes, particularly tumor-infiltrating Vγ9Vδ2 T-lymphocytes. The molecular circuitries determi
Externí odkaz:
https://doaj.org/article/339f95a15a81485b9051ea494da23165
Autor:
Iris Chiara Salaroglio, Dimas Carolina Belisario, Paolo Bironzo, Preeta Ananthanarayanan, Luisa Ricci, Sabrina Digiovanni, Simona Fontana, Francesca Napoli, Alberto Sandri, Chiara Facolmatà, Roberta Libener, Valentina Comunanza, Federica Grosso, Elena Gazzano, Francesco Leo, Riccardo Taulli, Federico Bussolino, Luisella Righi, Mauro Giulio Papotti, Silvia Novello, Giorgio Vittorio Scagliotti, Chiara Riganti, Joanna Kopecka
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background The combination of pemetrexed and cisplatin remains the reference first-line systemic therapy for malignant pleural mesothelioma (MPM). Its activity is moderate because of tumor aggressiveness, immune-suppressive environment and r
Externí odkaz:
https://doaj.org/article/da52a5cccfcf413bae005aae8e780d71
Autor:
Gamal Eldein Fathy Abd-ellatef, Elena Gazzano, Ahmed H. El-Desoky, Ahmed R. Hamed, Joanna Kopecka, Dimas Carolina Belisario, Costanzo Costamagna, Mohamed Assem S. Marie, Sohair R. Fahmy, Abdel-Hamid Z. Abdel-Hamid, Chiara Riganti
Publikováno v:
Pharmacological Research, Vol 189, Iss , Pp 106708- (2023)
Externí odkaz:
https://doaj.org/article/bfe63ecb3a0845558d14096a808aade6