Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joanna Karolina Ledwon"'
Publikováno v:
International Journal of Molecular Medicine. 34:1647-1654
Obesity contributes to the development of non-alcoholic fatty liver disease (NAFLD), which is characterized by the upregulated expression of two key inflammatory mediators: tumor necrosis factor (Tnfa) and monocyte chemotactic protein 1 (Mcp1; also k
Autor:
Jerzy Ostrowski, Kazimiera Pysniak, Michal Mikula, Marek Woszczyński, Krzysztof Goryca, Monika Nesteruk, Joanna Karolina Ledwon, Ewa E. Hennig, Agnieszka Paziewska, Bożena Walewska-Zielecka
Publikováno v:
Journal of Cellular and Molecular Medicine
One of the main questions regarding nonalcoholic fatty liver disease is the molecular background of the transition from simple steatosis (SS) to the inflammatory and fibrogenic condition of steatohepatitis (NASH). We examined the gene expression chan
Autor:
Marek Woszczyński, Jerzy Ostrowski, Tymon Rubel, Monika Nesteruk, Ewa E. Hennig, Michalina Dabrowska, Krzysztof Goryca, Agnieszka Paziewska, Michal Mikula, Joanna Karolina Ledwon, Michal Dadlez, Jakub Karczmarski, Artur Dzwonek
Publikováno v:
Functional & Integrative Genomics
Although mitochondrial dysfunction is implicated in the pathogenesis of obesity, the molecular mechanisms underlying obesity-related metabolic abnormalities are not well established. We performed mitochondrial quantitative proteomic and whole transcr
Autor:
Joanna Karolina Ledwon, Jerzy Ostrowski, Ewa E. Hennig, Dorota Nowakowska, Anna Niwińska, Natalia Maryan, Krzysztof Goryca
Publikováno v:
BMC Cancer
Background Breast cancer is the most common type of cancer and the second leading cause of cancer-death among women in Poland. The known high-risk mutations account for 25% of familial aggregation cases and 5% of total breast cancer predisposition. G
Autor:
Urszula Kuklinska, Jerzy Ostrowski, Michalina Dabrowska, Michal Mikula, Maria Kulecka, Marta Grzelak, Marta Miaczynska, Joanna Karolina Ledwon, Jakub Karczmarski, Krzysztof Ginalski, Izabela Rumienczyk, Krzysztof Goryca, Malgorzata Statkiewicz, Karol Bomsztyk, Katarzyna Paczkowska, Magdalena Skrzypczak, Kamil Jastrzębski
Publikováno v:
Europe PubMed Central
Nucleic Acids Research
Nucleic Acids Research
Genome-wide mechanisms that coordinate expression of subsets of functionally related genes are largely unknown. Recent studies show that receptor tyrosine kinases and components of signal transduction cascades including the extracellular signal-regul
Autor:
Krzysztof Przytulski, Ewa E. Hennig, Jerzy Ostrowski, Georg Homuth, Jaroslaw Regula, Artur A. Antoniewicz, Monika Nesteruk, Jakub Karczmarski, Teresa Starzyńska, Natalia Maryan, Aneta Majewska, Jan Wolski, Alexander Teumer, Agnieszka Paziewska, Andrzej Rutkowski, Pawel Gaj, Joanna Karolina Ledwon
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35307 (2012)
PLoS ONE
PLoS ONE
BackgroundProstate cancer (PCa) and colorectal cancer (CRC) are the most commonly diagnosed cancers and cancer-related causes of death in Poland. To date, numerous single nucleotide polymorphisms (SNPs) associated with susceptibility to both cancer t