Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joanna Kalafut"'
Autor:
Justyna Magdalena Hermanowicz, Anna Szymanowska, Beata Sieklucka, Robert Czarnomysy, Krystyna Pawlak, Anna Bielawska, Krzysztof Bielawski, Joanna Kalafut, Alicja Przybyszewska, Arkadiusz Surazynski, Adolfo Rivero-Muller, Mariusz Mojzych, Dariusz Pawlak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 535-548 (2021)
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in men and in women. The impact of the new pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide (MM-129) was evaluated against human colon cancer in vitro and in zebra
Externí odkaz:
https://doaj.org/article/16356bbb3b0d4b34b72198eeb4905e86
Autor:
Dariusz Rozkiewicz, Justyna Magdalena Hermanowicz, Anna Tankiewicz-Kwedlo, Beata Sieklucka, Krystyna Pawlak, Robert Czarnomysy, Krzysztof Bielawski, Arkadiusz Surazynski, Joanna Kalafut, Alicja Przybyszewska, Mariusz Koda, Katarzyna Jakubowska, Adolfo Rivero-Muller, Dariusz Pawlak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1697-1711 (2020)
Recombinant human erythropoietin (Epo) is an effective and convenient treatment for cancer-related anaemia. In our study for the first time, we evaluated the effect of simultaneous use of Epo and Bruton’s tyrosine kinase (BTK) inhibitor LFM-A13 on
Externí odkaz:
https://doaj.org/article/418377d1f791473ea76404dcb6f5a02c
Autor:
Anna Wawruszak, Jarogniew J. Luszczki, Joanna Kalafut, Karolina Okla, Marta Halasa, Adolfo Rivero-Muller, Andrzej Stepulak
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3663 (2019)
The aim of this study was to investigate the influence of the Notch1 activity level on the pharmacological interaction between cisplatin (CDDP) and two histone deacetylase inhibitors (HDIs)—valproic acid (VPA) and vorinostat (SAHA) in the triple ne
Externí odkaz:
https://doaj.org/article/d7c99994cb1f406fb4a580894dbde5e6
Synthetic biology involves the generation of logic circuits to create or control biological functions and behaviours by engineering interconnected genetic elements such as promoters, repressors, and transcriptional activators. CRISPR discovery, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3d4c565d36e070f00b56c04a044769e
https://doi.org/10.1101/2023.03.16.533022
https://doi.org/10.1101/2023.03.16.533022
Autor:
Arkadiusz Czerwonka, Joanna Kałafut, Shaoxia Wang, Alinda Anameric, Alicja Przybyszewska-Podstawka, Mervi Toriseva, Matthias Nees
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116822- (2024)
Aberration of Notch signaling is one of the key events involved in the development and progression of head and neck squamous cell carcinoma (HNSCC). The Notch pathway controls the tissue-specific differentiation of normal squamous epithelial cells an
Externí odkaz:
https://doaj.org/article/dc173e8c518f48df9aacca0bb86ccdd1
Autor:
Arkadiusz Czerwonka, Joanna Kałafut, Shaoxia Wang, Alinda Anameric, Alicja Przybyszewska-Podstawka, Jesse Mattsson, Mahtab Karbasian, Doriane Le Manach, Mervi Toriseva, Matthias Nees
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Notch signalling is one of the key molecular pathways involved in cell-to-cell signal transduction. Although the mechanisms of action of the NOTCH receptors are already relatively well known, their biological implications remain unclear, esp
Externí odkaz:
https://doaj.org/article/9c02c842501f4c619df5ba8b69591f58
Autor:
Lidia Borkiewicz, Joanna Kalafut, Karolina Dudziak, Alicja Przybyszewska-Podstawka, Ilona Telejko
Publikováno v:
Cancers, Vol 13, Iss 2643, p 2643 (2021)
Cancers
Cancers
Simple Summary Advances in RNA sequencing (RNA-seq) have led to the identification of long non-coding RNAs (lncRNAs). Molecular studies on these molecules have shown that lncRNAs act as important regulators of gene expression at the transcriptional a
Autor:
Joanna Kałafut, Jakub Czapiński, Alicja Przybyszewska-Podstawka, Arkadiusz Czerwonka, Adrian Odrzywolski, Cecilia Sahlgren, Adolfo Rivero-Müller
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract The Notch signaling pathway is a crucial regulator of cell differentiation as well as tissue organization, whose deregulation is linked to the pathogenesis of different diseases. NOTCH1 plays a key role in breast cancer progression by increa
Externí odkaz:
https://doaj.org/article/1ae1335d10fe49398ddb79f9c774c978
Autor:
Joanna Kałafut, Arkadiusz Czerwonka, Karolina Czapla, Alicja Przybyszewska-Podstawka, Justyna Magdalena Hermanowicz, Adolfo Rivero-Müller, Lidia Borkiewicz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12579 (2023)
Notch1 signalling plays a multifaceted role in tissue development and homeostasis. Currently, due to the pivotal role of Notch1 signalling, the relationship between NOTCH1 expression and the development of health disorders is being intensively studie
Externí odkaz:
https://doaj.org/article/8d2b67e2059b46c4bae2eede396ef578
Autor:
Kamila Szymańska, Joanna Kałafut, Alicja Przybyszewska, Beata Paziewska, Grzegorz Adamczuk, Michał Kiełbus, Adolfo Rivero-Müller
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Follicle stimulating hormone (FSH) plays a key role in human reproduction through, among others, induction of spermatogenesis in men and production of estrogen in women. The function FSH is performed upon binding to its cognate receptor—follicle-st
Externí odkaz:
https://doaj.org/article/6ddb52e47348401292b476a96f51d0be