Comparison of seven different anesthesia protocols for nicotine pharmacologic magnetic resonance imaging in rat

Autor: Artem Shatillo, Johanna Närväinen, Markus M. Forsberg, Olli Gröhn, Jaakko Paasonen, Raimo A. Salo, Joanna K. Huttunen

Publikováno v: Paasonen, J, Salo, R A, Shatillo, A, Forsberg, M M, Närväinen, J, Huttunen, J K & Gröhn, O 2016, ' Comparison of seven different anesthesia protocols for nicotine pharmacologic magnetic resonance imaging in rat ', European Neuropsychopharmacology, vol. 26, no. 3, pp. 518-531 . https://doi.org/10.1016/j.euroneuro.2015.12.034

Pharmacologic MRI (phMRI) is a non-invasive in vivo imaging method, which can evaluate the drug effects on the brain and provide complementary information to ex vivo techniques. The preclinical phMRI studies usually require anesthesia to reduce the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718924ef1aaa1378078533d2a3833f1e
https://doi.org/10.1016/j.euroneuro.2015.12.034

Detection of Hyperexcitability by Functional Magnetic Resonance Imaging after Experimental Traumatic Brain Injury

Autor: Carmen Barba, Gabriella Colicchio, Alejandra Sierra Lopez, Joanna K. Huttunen, Olli Gröhn, Asla Pitkänen, Xavier Ekolle Ndode-Ekane, Juha-Pekka Niskanen, Artem Shatillo, Antti M. Airaksinen

Publikováno v: Journal of neurotrauma. 35(22)

Diagnosis of ongoing epileptogenesis and associated hyperexcitability after brain injury is a major challenge. Given that increased neuronal activity in the brain triggers a blood oxygenation level-dependent (BOLD) response in functional magnetic res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba57b6a91e2d8df217cd6dd4bfa686a
https://pubmed.ncbi.nlm.nih.gov/30019618

Posttraumatic epilepsy — Disease or comorbidity?

Autor: Noora Huusko, Joanna K. Huttunen, Olli Gröhn, Asla Pitkänen, Riikka Immonen, Alejandra Sierra, Samuli Kemppainen, Tamuna Bolkvadze, Xavier Ekolle Ndode-Ekane

Publikováno v: Epilepsy & Behavior. 38:19-24

Traumatic brain injury (TBI) can cause a myriad of sequelae depending on its type, severity, and location of injured structures. These can include mood disorders, posttraumatic stress disorder and other anxiety disorders, personality disorders, aggre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd894431ebbf1946980d3872be9631b3
https://doi.org/10.1016/j.yebeh.2014.01.013

Gait Impairment in a Rat Model of Focal Cerebral Ischemia

Autor: Joanna K. Huttunen, Jukka Jolkkonen, Kristina Kuptsova, Saara Parkkinen, Francisco J. Ortega, Ina M. Tarkka

Publikováno v: Stroke Research and Treatment
Stroke Research and Treatment, Vol 2013 (2013)

The availability of proper tests for gait evaluation following cerebral ischemia in rats has been limited. The automated, quantitative CatWalk system, which was initially designed to measure gait in models of spinal cord injury, neuropathic pain, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406b204bb53d269e566646788b75cffa
https://doi.org/10.1155/2013/410972

Simultaneous BOLD fMRI and local field potential measurements during kainic acid-induced seizures

Autor: Asla Pitkänen, Olli Gröhn, Joanna K. Huttunen, Shahryar K. Hekmatyar, Risto A. Kauppinen, Juha-Pekka Niskanen, Neil P. Jerome, Antti M. Airaksinen

Publikováno v: Epilepsia. 53:1245-1253

Summary Purpose: To investigate how kainic acid–induced epileptiform activity is related to hemodynamic changes probed by blood oxygenation level–dependent functional magnetic resonance imaging (BOLD fMRI). Methods: Epileptiform activity was indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ff6560ecb52799ca00cc27c83585c7c
https://doi.org/10.1111/j.1528-1167.2012.03539.x