Výsledky vyhledávání - "Joanna Hagelberger"

Akademický článek

Insertion Specificity of the hATx-6 Transposase of Hydra magnipapillata

Autor: Paul Riggs, George Blundell-Hunter, Joanna Hagelberger, Guoping Ren, Laurence Ettwiller, Mehmet Berkmen

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)

Transposable elements (TE) are mobile genetic elements, present in all domains of life. They commonly encode a single transposase enzyme, that performs the excision and reintegration reactions, and these enzymes have been used in mutagenesis and crea

Externí odkaz: https://doaj.org/article/de574cf1272642078eaddcdfe0505d77

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Molecular insights into the μ-opioid receptor biased signaling

Autor: Damien Maurel, Hélène Déméné, Remy Sounier, Jérôme Golebiowski, Xiaojing Cong, Julie Saint-Paul, Fanny Peysson, Ieva Vasiliauskaité-Brooks, Sébastien Granier, Joanna Hagelberger

SUMMARYGPCR functional selectivity has opened new opportunities for the design of safer drugs. Ligands orchestrate GPCR signaling cascades by modulating the receptor conformational landscape. Our study provides insights into the dynamic mechanism ena

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2c2ea04e68f0231882d24661b15fd06
https://doi.org/10.1101/2021.03.22.436421

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Molecular insights into the biased signaling mechanism of the μ-opioid receptor

Autor: Damien Maurel, Xiaojing Cong, Joanna Hagelberger, Fanny Peysson, Sébastien Granier, Hélène Déméné, Jérôme Golebiowski, Remy Sounier, Julie Saint-Paul, Ieva Vasiliauskaité-Brooks

Publikováno v: Molecular Cell
Molecular Cell, Elsevier, In press, ⟨10.1016/j.molcel.2021.07.033⟩
Molecular Cell, Elsevier, In press, 81 (20), pp.4165-4175.e6. ⟨10.1016/j.molcel.2021.07.033⟩

International audience; GPCR functional selectivity opens new opportunities for the design of safer drugs. Ligands orchestrate GPCR signaling cascades by modulating the receptor conformational landscape. Our study provides insights into the dynamic m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a896a266663e292ffa3878ad708fc2a4
https://doi.org/10.1016/j.molcel.2021.07.033

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1H, 13C and 15N backbone chemical shift assignments of camelid single-domain antibodies against active state µ-opioid receptor

Autor: Hélène Déméné, Yinshan Yang, Sébastien Granier, Remy Sounier, Joanna Hagelberger

Publikováno v: Biomolecular NMR Assignments
Biomolecular NMR Assignments, 2017, 11 (1), pp.117-121. ⟨10.1007/s12104-017-9733-z⟩
Biomolecular NMR Assignments, Springer, 2017, 11 (1), pp.117-121. ⟨10.1007/s12104-017-9733-z⟩

International audience; Nanobodies are single chain antibodies that have become a highly valuable and versatile tool for biomolecular and therapeutic research. One application field is the stabilization of active states of flexible proteins, among wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d8de019a4412309b5521f6d1ce5247
https://doi.org/10.1007/s12104-017-9733-z

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