Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joanna F. Mulvaney"'
Autor:
Ruishuang Geng, Teppei Noda, Joanna F Mulvaney, Vincent Y W Lin, Albert S B Edge, Alain Dabdoub
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148339 (2016)
In the inner ear Wnt signaling is necessary for proliferation, cell fate determination, growth of the cochlear duct, polarized orientation of stereociliary bundles, differentiation of the periotic mesenchyme, and homeostasis of the stria vascularis.
Externí odkaz:
https://doaj.org/article/3f770b22005f4111953a41c91acfd8d4
Autor:
Danielle R. Lenz, Rory Kirchner, Lihong Xie, Hao Chiang, Anshula Samarajeewa, Albert S.B. Edge, Joanna F. Mulvaney, Alain Dabdoub
Publikováno v:
Development (Cambridge, England)
Lack of sensory hair cell (HC) regeneration in mammalian adults is a major contributor to hearing loss. In contrast, the neonatal mouse cochlea retains a transient capacity for regeneration, and forced Wnt activation in neonatal stages promotes suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b110e93ba5edc02f68d92014e709b381
https://doi.org/10.1242/dev.166579
https://doi.org/10.1242/dev.166579
Publikováno v:
Biology of the Cell. 107:41-60
Background information The vertebrate basic helix-loop-helix transcription factor Atoh1 is essential for maturation and survival of mechanosensory hair cells of the inner ear, neurogenesis, differentiation of the intestine, homeostasis of the colon a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd71966e11a7ebfb6e95414baae1e74
https://doi.org/10.1111/boc.201400078
https://doi.org/10.1111/boc.201400078
Autor:
Alain Dabdoub, Lingxiang Hu, Albert S.B. Edge, Fuxin Shi, Joanna F. Mulvaney, Bonnie E. Jacques
Publikováno v:
The Journal of Neuroscience. 34:6470-6479
The development of hair cells in the auditory system can be separated into steps; first, the establishment of progenitors for the sensory epithelium, and second, the differentiation of hair cells. Although the differentiation of hair cells is known t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a80ce077286330ff1273c248b16bae
https://doi.org/10.1523/jneurosci.4305-13.2014
https://doi.org/10.1523/jneurosci.4305-13.2014
Autor:
Joanna F. Mulvaney, Toshio Suda, W. W. Sun, Bonnie E. Jacques, Keiyo Takubo, A. Yatteau, W. Yamada, Alain Dabdoub
Publikováno v:
Developmental Dynamics. 242:179-188
Background: In the cochlea, patterning of the organ of Corti is tightly regulated to produce a single row of sound-detecting inner hair cells and three rows of outer hair cells, which amplify and refine the signal. The recently identified R-Spondin f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd939d01919aabdeff8398b232769596
https://doi.org/10.1002/dvdy.23908
https://doi.org/10.1002/dvdy.23908
Autor:
Cathrine Thompkins, Koji Nishimura, Shuh Yow Lin, Willy W. Sun, Joanna F. Mulvaney, Teppei Noda, Alain Dabdoub, Allison B. Coffin
Publikováno v:
Scientific Reports
Here we present spatio-temporal localization of Kremen1, a transmembrane receptor, in the mammalian cochlea and investigate its role in the formation of sensory organs in mammal and fish model organisms. We show that Kremen1 is expressed in prosensor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3eb3ac064dd50a7f81f1cb8a748061
Publikováno v:
Biology of the cell. 107(2)
The vertebrate basic helix-loop-helix transcription factor Atoh1 is essential for maturation and survival of mechanosensory hair cells of the inner ear, neurogenesis, differentiation of the intestine, homeostasis of the colon and is implicated in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5df8db9735263b92405ae2f923f82ce
https://pubmed.ncbi.nlm.nih.gov/25412697
https://pubmed.ncbi.nlm.nih.gov/25412697
Autor:
Joanna F. Mulvaney, Alain Dabdoub
Atoh1 (also known as Math1, Hath1, and Cath1 in mouse, human, and chicken, respectively) is a proneural basic helix–loop–helix (bHLH) transcription factor that is required in a variety of developmental contexts. Atoh1 is involved in differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef4cca86c183d5b4deba9ed8b622f51
https://europepmc.org/articles/PMC3346892/
https://europepmc.org/articles/PMC3346892/
