Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joanna E. Zawacka-Pankau"'
Autor:
Vera V. Grinkevich, Aparna Vema, Karin Fawkner, Natalia Issaeva, Virginia Andreotti, Eleanor R. Dickinson, Elisabeth Hedström, Clemens Spinnler, Alberto Inga, Lars-Gunnar Larsson, Anders Karlén, Margareta Wilhelm, Perdita E. Barran, Andrei L. Okorokov, Galina Selivanova, Joanna E. Zawacka-Pankau
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Restoration of the p53 tumor suppressor for personalised cancer therapy is a promising treatment strategy. However, several high-affinity MDM2 inhibitors have shown substantial side effects in clinical trials. Thus, elucidation of the molecular mecha
Externí odkaz:
https://doaj.org/article/6e3200658e124c519165fca58876e250
Publikováno v:
International journal of molecular sciences. 23(13)
Despite the recent development of precision medicine and targeted therapies, lung cancer remains the top cause of cancer-related mortality worldwide. The patients diagnosed with metastatic disease have a five-year survival rate lower than 6%. In meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee44bc269b98aacc1ad9a8a0a070d507
https://pubmed.ncbi.nlm.nih.gov/35806218
https://pubmed.ncbi.nlm.nih.gov/35806218
Autor:
Vera V. Grinkevich, Aparna Vema, Karin Fawkner, Natalia Issaeva, Virginia Andreotti, Eleanor R. Dickinson, Elisabeth Hedström, Clemens Spinnler, Alberto Inga, Lars-Gunnar Larsson, Anders Karlén, Margareta Wilhelm, Perdita E. Barran, Andrei L. Okorokov, Galina Selivanova, Joanna E. Zawacka-Pankau
Restoration of the p53 tumor suppressor for personalised cancer therapy is a promising strategy. However, high-affinity MDM2 inhibitors have shown substantial side effects in clinical trials. Thus, elucidation of the molecular mechanisms of action of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc285934fd6328f7bd97b29f69441c5
https://doi.org/10.1101/2021.12.24.474003
https://doi.org/10.1101/2021.12.24.474003
