Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joanna E, Cobb"'
Autor:
Joanna E Cobb, Darren Plant, Edward Flynn, Meriem Tadjeddine, Philippe Dieudé, François Cornélis, Lisbeth Ärlestig, Solbritt Rantapää Dahlqvist, George Goulielmos, Dimitrios T Boumpas, Prodromos Sidiropoulos, Sophine B Krintel, Lykke M Ørnbjerg, Merete L Hetland, Lars Klareskog, Thomas Haeupl, Andrew Filer, Christopher D Buckley, Karim Raza, Torsten Witte, Reinhold E Schmidt, Oliver FitzGerald, Douglas Veale, Stephen Eyre, Jane Worthington
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66456 (2013)
ObjectivesGenome-wide association studies have facilitated the identification of over 30 susceptibility loci for rheumatoid arthritis (RA). However, evidence for a number of potential susceptibility genes have not so far reached genome-wide significa
Externí odkaz:
https://doaj.org/article/628ccdef86944f8a88af42fb2ef3e519
Autor:
Jane E Munro, John Bowes, Marta Brozynska, Gad Abraham, Rodrigo Cánovas, Wendy Thomson, Samantha L. Smith, Joanna E. Cobb, Hakon Hakonarson, Michael Inouye, Justine A. Ellis, Yun Li
Publikováno v:
Cánovas, R, Cobb, J, Brozynska, M, Bowes, J, Li, Y R, Smith, S L, Hakonarson, H, Thomson, W, Ellis, J A, Abraham, G, Munro, J E & Inouye, M 2020, ' Genomic risk scores for juvenile idiopathic arthritis and its subtypes ', Annals of the rheumatic diseases . https://doi.org/10.1136/annrheumdis-2020-217421
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases
ObjectivesJuvenile idiopathic arthritis (JIA) is an autoimmune disease and a common cause of chronic disability in children. Diagnosis of JIA is based purely on clinical symptoms, which can be variable, leading to diagnosis and treatment delays. Desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779fc9ebaf89448f1b9d7245c65f6fc0
https://www.research.manchester.ac.uk/portal/en/publications/genomic-risk-scores-for-juvenile-idiopathic-arthritis-and-its-subtypes(839b8c4e-5fff-4844-9c73-db82c1ea303d).html
https://www.research.manchester.ac.uk/portal/en/publications/genomic-risk-scores-for-juvenile-idiopathic-arthritis-and-its-subtypes(839b8c4e-5fff-4844-9c73-db82c1ea303d).html
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5081 (2009)
BACKGROUND: The functional polymorphism that explains the established association of the androgen receptor (AR) with androgenetic alopecia (AGA) remains unidentified, but Copy Number Variation (CNV) might be relevant. CNV involves changes in copy num
Externí odkaz:
https://doaj.org/article/f5714e57159a4b5caab7a2f53c05b0e2
Autor:
Katrina J. Allen, David Martino, Thanh D. Dang, Melanie R Neeland, Joanna E. Cobb, Mimi L.K. Tang, Justine A. Ellis, Peter Vuillermin, Alice Barnett, Richard Saffery
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Food allergy poses a significant clinical and public health burden affecting 2–10% of infants. Using integrated DNA methylation and transcriptomic profiling, we found that polyclonal activation of naive CD4+ T cells through the T cell receptor resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531ddc7e0fcfcca4e47934697dbf27ab
https://doi.org/10.1038/s41467-018-05608-4
https://doi.org/10.1038/s41467-018-05608-4
Autor:
Angela Pezic, Jonathan D Akikusa, Roger C. Allen, Anne-Louise Ponsonby, Jane E Munro, Justine A. Ellis, Terence Dwyer, Joanna E. Cobb, Rachel Chiaroni-Clarke
Publikováno v:
Photochemistry and photobiology. 95(3)
Cutaneous sun exposure is an important determinant of circulating vitamin D. Both sun exposure and vitamin D have been inversely associated with risk of autoimmune disease. In juvenile idiopathic arthritis (JIA), low circulating vitamin D appears com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c9d92dd3fad7c13426d678349f1102
https://pubmed.ncbi.nlm.nih.gov/30378692
https://pubmed.ncbi.nlm.nih.gov/30378692
Autor:
Jeffrey M. Craig, Nicholas C. Wong, LW Yip, R Bosnich, Stephen B. Harrap, Justine A. Ellis, Joanna E. Cobb, Jennifer Martinick, Rodney Sinclair, Richard Saffery
Publikováno v:
British Journal of Dermatology. 165:210-213
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5e35c4951f8faeab01222af79151af
https://doi.org/10.1111/j.1365-2133.2011.10335.x
https://doi.org/10.1111/j.1365-2133.2011.10335.x
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 35:372-375
1. The search for DNA sequence variants for complex human polygenic conditions has been a strong focus of recent genetic research. While gene loci have been identified, few variants in the coding sequences of these genes have been found, suggesting t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1eab99f7ba3a7c6179fee72a50a2b91
https://doi.org/10.1111/j.1440-1681.2008.04880.x
https://doi.org/10.1111/j.1440-1681.2008.04880.x
Publikováno v:
Experimental Dermatology. 19:1026-1028
Please cite this paper as: Evidence for two independent functional variants for androgenetic alopecia around the androgen receptor gene. Experimental Dermatology 2010; 19: 1026–1028. Abstract: The gene encoding the androgen receptor (AR) is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa9abe05240fbcb2bf96bbb944e84236
https://doi.org/10.1111/j.1600-0625.2010.01132.x
https://doi.org/10.1111/j.1600-0625.2010.01132.x
Autor:
Charles E. Schwartz, Quang M. Bui, Cindy Skinner, Elva Z. Shi, Danuta Z. Loesch, Jacqueline K. Hewitt, David E. Godler, Yoshimi Inaba, Alison Arvaj, Jonathon Cohen, Randi J Hagerman, Sylvia A Metcalfe, Howard R. Slater, Joanna E. Cobb, Amy S Herlihy, Tiffany Wotton, David Francis, John L. Hopper, Kate Pope, David J. Amor
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics. 15(4)
We show that a novel fragile X–related epigenetic element 2 FMR1 methylation test can be used along with a test for sex-determining region Y (SRY) to provide the option of combined fragile X syndrome and sex chromosome aneuploidy newborn screening.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15638a09765b55bd25c4d6e3c8614d0
https://pubmed.ncbi.nlm.nih.gov/23060046
https://pubmed.ncbi.nlm.nih.gov/23060046
Publikováno v:
Experimental dermatology. 19(11)
The gene encoding the androgen receptor (AR) is associated with male pattern baldness (androgenetic alopecia - AGA). In case-control and family analyses, we mapped AR and the adjacent intergenic regions. We found evidence for association with two ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d9a53ffcf41d257877a07f4799e9978
https://pubmed.ncbi.nlm.nih.gov/21073542
https://pubmed.ncbi.nlm.nih.gov/21073542