Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joanna Demilly"'
Autor:
Aurélien Leray, Pierre-Alban Lalys, Juliette Varin, Mohammed Bouzelha, Audrey Bourdon, Dimitri Alvarez-Dorta, Karine Pavageau, Sébastien Depienne, Maia Marchand, Anthony Mellet, Joanna Demilly, Jean-Baptiste Ducloyer, Tiphaine Girard, Bodvaël Fraysse, Mireille Ledevin, Mickaël Guilbaud, Sébastien G. Gouin, Eduard Ayuso, Oumeya Adjali, Thibaut Larcher, Thérèse Cronin, Caroline Le Guiner, David Deniaud, Mathieu Mével
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116148- (2024)
Decades of biological and clinical research have led to important advances in recombinant adeno-associated viruses rAAV-based gene therapy gene therapy. However, several challenges must be overcome to fully exploit the potential of rAAV vectors. Inno
Externí odkaz:
https://doaj.org/article/1ed978775aad41fbbbc3787da57c93b5
Autor:
Gregory Gauvain, Himanshu Akolkar, Antoine Chaffiol, Fabrice Arcizet, Mina A. Khoei, Mélissa Desrosiers, Céline Jaillard, Romain Caplette, Olivier Marre, Stéphane Bertin, Claire-Maelle Fovet, Joanna Demilly, Valérie Forster, Elena Brazhnikova, Philippe Hantraye, Pierre Pouget, Anne Douar, Didier Pruneau, Joël Chavas, José-Alain Sahel, Deniz Dalkara, Jens Duebel, Ryad Benosman, Serge Picaud
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Gauvain et al demonstrate that optogenetic therapy using the AAV2.7m8- ChR-tdT construct can partially restore vision in non-human primates to levels above those considered legally-blind. This study enables the identification of the most suitable con
Externí odkaz:
https://doaj.org/article/0b4ca90d06f64da69afaff7c49d68f90
Autor:
Che Serguera, Lev Stimmer, Claire-Maelle Fovet, Philippe Horellou, Vanessa Contreras, Nicolas Tchitchek, Julie Massonneau, Carole Leroy, Audrey Perrin, Julien Flament, Philippe Hantraye, Joanna Demilly, Romain Marignier, Pascale Chrétien, Bert‘t Hart, Jean Boutonnat, Clovis Adam, Roger Le-Grand, Kumaran Deiva
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Autoantibodies against myelin oligodendrocyte glycoprotein (anti-MOG-Abs) occur in a majority of children with acquired demyelinating syndromes (ADS) and physiopathology is still under investigation. As cynomolgus macaques immuniz
Externí odkaz:
https://doaj.org/article/e1038794ee40410a885a01b24354e627
Autor:
Aurelien Leray, Pierre-Alban Lalys, Juliette Varin, Mohammed Bouzelha, Audrey Bourdon, Dimitri Alvarez-Dorta, Karine Pavageau, Sebastien Depienne, Maia Marchand, Anthony Mellet, Joanna Demilly, Jean-Baptiste Ducloyer, Tiphaine Girard, Bodval Fraysse, Mireille Ledevin, Mickael Guilbaud, Sebastien G. Gouin, Eduard Ayuso, Oumeya Adjali, Thibaut Larcher, Therese Cronin, Caroline Le Guiner, David Deniaud, Mathieu Mevel
Decades of biological and clinical research have led to important advances in recombinant adeno-associated viruses rAAV-based gene therapy gene therapy. However, several challenges must be overcome to fully exploit the potential of rAAV vectors. Inno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33fdeaf96dcd33201a922c4fba14ec65
https://doi.org/10.26434/chemrxiv-2023-6xnn8
https://doi.org/10.26434/chemrxiv-2023-6xnn8
Autor:
José-Alain Sahel, Fabrice Arcizet, Philippe Hantraye, Serge Picaud, Gregory Gauvain, Claire-Maëlle Fovet, Jens Duebel, Pierre Pouget, Mina A. Khoei, Deniz Dalkara, Joël Chavas, Melissa Desrosiers, Elena Brazhnikova, Ryad Benosman, Didier Pruneau, Olivier Marre, Antoine Chaffiol, Joanna Demilly, Himanshu Akolkar, Anne Douar, Valérie Forster, Romain Caplette, Céline Jaillard, Stéphane Bertin
Restoring vision using optogenetics is an ideal medical application because the eye offers a direct window to access and stimulate the pathological area: the retina. Optogenetic therapy could be applied to diseases with photoreceptor degeneration suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d29dcc167fa17ca377fe8e3ece29fe
https://doi.org/10.1101/2020.05.17.100230
https://doi.org/10.1101/2020.05.17.100230
Autor:
Céline Jaillard, Gregory Gauvain, Serge Picaud, Olivier Marre, Antoine Chaffiol, Fabrice Arcizet, Stéphane Bertin, Pierre Pouget, Jens Duebel, Didier Pruneau, Anne Douar, Joël Chavas, Romain Caplette, Joanna Demilly, Elena Brazhnikova, Philippe Hantraye, Melissa Desrosiers, Valérie Forster, Claire-Maëlle Fovet, Mina A. Khoei, José-Alain Sahel, Himanshu Akolkar, Deniz Dalkara, Ryad Benosman
Publikováno v:
Communications Biology
Communications Biology, Nature Publishing Group, 2021, 4 (1), pp.125. ⟨10.1038/s42003-020-01594-w⟩
Communications Biology, 2021, 4 (1), pp.125. ⟨10.1038/s42003-020-01594-w⟩
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology, Nature Publishing Group, 2021, 4 (1), pp.125. ⟨10.1038/s42003-020-01594-w⟩
Communications Biology, 2021, 4 (1), pp.125. ⟨10.1038/s42003-020-01594-w⟩
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Vision restoration is an ideal medical application for optogenetics, because the eye provides direct optical access to the retina for stimulation. Optogenetic therapy could be used for diseases involving photoreceptor degeneration, such as retinitis
Autor:
Walter Habeler, Marc Peschanski, Elena Brazhnikova, Olivier Goureau, José-Alain Sahel, Karim Ben M'Barek, Mohamed Jarraya, Alexandra Plancheron, Claire-Maëlle Fovet, Joanna Demilly, Christelle Monville, Stéphane Bertin, Ana Bejanariu, Céline Jaillard
Publikováno v:
Biomaterials
Biomaterials, Elsevier, 2020, 230, pp.119603. ⟨10.1016/j.biomaterials.2019.119603⟩
Biomaterials, 2020, 230, pp.119603. ⟨10.1016/j.biomaterials.2019.119603⟩
Biomaterials, Elsevier, 2020, 230, pp.119603. ⟨10.1016/j.biomaterials.2019.119603⟩
Biomaterials, 2020, 230, pp.119603. ⟨10.1016/j.biomaterials.2019.119603⟩
International audience; Age-related macular degeneration as well as some forms of Retinitis Pigmentosa (RP) are characterized by a retinal degeneration involving the retinal pigment epithelium (RPE). Various strategies were proposed to cure these dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507adffd1356e0f60d616eabd2014985
https://hal.sorbonne-universite.fr/hal-02485645/document
https://hal.sorbonne-universite.fr/hal-02485645/document
Autor:
Joanna Demilly, Julie Massonneau, Romain Marignier, Roger LeGrand, Jean Boutonnat, Philippe Hantraye, Bert A. 't Hart, Nicolas Tchitchek, Audrey Perrin, Julien Flament, Ché Serguera, Vanessa Contreras, Carole Leroy, Lev Stimmer, Claire-Maëlle Fovet, Pascale Chrétien, Philippe Horellou, Kumaran Deiva, Clovis Adam
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, 2019, 16, pp.244. ⟨10.1186/s12974-019-1637-7⟩
Journal of neuroinflammation, 16(1):244. BMC
Journal of Neuroinflammation, BioMed Central, 2019, 16 (1), pp.244. ⟨10.1186/s12974-019-1637-7⟩
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Journal of Neuroinflammation, 2019, 16, pp.244. ⟨10.1186/s12974-019-1637-7⟩
Journal of neuroinflammation, 16(1):244. BMC
Journal of Neuroinflammation, BioMed Central, 2019, 16 (1), pp.244. ⟨10.1186/s12974-019-1637-7⟩
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Background Autoantibodies against myelin oligodendrocyte glycoprotein (anti-MOG-Abs) occur in a majority of children with acquired demyelinating syndromes (ADS) and physiopathology is still under investigation. As cynomolgus macaques immunized with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a1f4346110a959126490ae7f9924d5
https://cea.hal.science/cea-02397764/document
https://cea.hal.science/cea-02397764/document
Autor:
Lev Stimmer, Julien Flament, Lionel Hervé, L. Watroba, M. Berger, J.-M. Dinten, P. Aubourg, Anne Planat-Chrétien, Joanna Demilly
Publikováno v:
ECBO 2015
ECBO 2015, Jun 2015, Munich, Germany. 9538, pp.953806, 2015, SPIE Proceedings Diffuse Optical Imaging V, ⟨10.1117/12.2183733⟩
ECBO 2015, Jun 2015, Munich, Germany. 9538, pp.953806, 2015, SPIE Proceedings Diffuse Optical Imaging V, ⟨10.1117/12.2183733⟩
International audience; We conducted a preclinical assessment on young macaques aimed at detecting white matter lesions. We present the protocol we implemented to achieve the lesions detection using a bedside non-invasive optical-based Time-Resolved
Autor:
Philippe Hantraye, Claire-Maëlle Fovet, Valérie Forster, José-Alain Sahel, Joanna Demilly, Kevin Blaize, Pierre Pouget, Paul-Henri Prevot, Serge Picaud, Himanshu Akolkar, Céline Nouvel-Jaillard, Elena Brazhnikova, Marion Lanoë, Paul Langlois, Fabrice Arcizet, Elric Esposito, Ryad Benosman, Guillaume Buc, Kevin Gehere, Mina A. Khoei, Elodie Bouillet, Guillaume Chenegros, Elisabeth Dubus, Omar Oubari, Pierre M. Daye, Henri Lorach, Manon Valet, Morgane Weissenburger, Nicolas Wattiez, Yannick LeMer, Martin Deterre, Ralf Hornig, Sami Dalouz
Publikováno v:
Nature Biomedical Engineering
Nature Biomedical Engineering, Nature Publishing Group, 2020, 4 (2), pp.172-180. ⟨10.1038/s41551-019-0484-2⟩
Nature Biomedical Engineering, 2020, 4 (2), pp.172-180. ⟨10.1038/s41551-019-0484-2⟩
Nature Biomedical Engineering, Nature Publishing Group, 2020, 4 (2), pp.172-180. ⟨10.1038/s41551-019-0484-2⟩
Nature Biomedical Engineering, 2020, 4 (2), pp.172-180. ⟨10.1038/s41551-019-0484-2⟩
Retinal dystrophies and age-related macular degeneration related to photoreceptor degeneration can cause blindness. In blind patients, although the electrical activation of the residual retinal circuit can provide useful artificial visual perception,