Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Joanna Crawford"'
Autor:
Arti M. Raghubar, Nicholas A. Matigian, Joanna Crawford, Leo Francis, Robert Ellis, Helen G. Healy, Andrew J. Kassianos, Monica S. Y. Ng, Matthew J. Roberts, Simon Wood, Andrew J. Mallett
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-9 (2023)
Abstract Perioperative immune checkpoint inhibitor (ICI) trials for intermediate high-risk clear cell renal cell carcinoma (ccRCC) have failed to consistently demonstrate improved patient outcomes. These unsuccessful ICI trials suggest that the tumou
Externí odkaz:
https://doaj.org/article/61bde8200489472a9c91dfe298700bf9
Autor:
Tuan Vo, Brad Balderson, Kahli Jones, Guiyan Ni, Joanna Crawford, Amanda Millar, Elissa Tolson, Matthew Singleton, Marija Kojic, Thomas Robertson, Shaun Walters, Onkar Mulay, Dharmesh D. Bhuva, Melissa J. Davis, Brandon J. Wainwright, Quan Nguyen, Laura A. Genovesi
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-28 (2023)
Abstract Background Medulloblastoma (MB) is a malignant tumour of the cerebellum which can be classified into four major subgroups based on gene expression and genomic features. Single-cell transcriptome studies have defined the cellular states under
Externí odkaz:
https://doaj.org/article/7b01e6e8430f4272932f8e0c58f61003
Autor:
Brett D. McKinnon, Samuel W. Lukowski, Sally Mortlock, Joanna Crawford, Sharat Atluri, Sugarniya Subramaniam, Rebecca L. Johnston, Konstantinos Nirgianakis, Keisuke Tanaka, Akwasi Amoako, Michael D. Mueller, Grant W. Montgomery
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Comparing single cell transcriptome data to clinical characteristics and in vitro growth profiles uncovers a potential role for divergent mesenchymal-derived stromal fibroblast maturation in endometriosis susceptibility.
Externí odkaz:
https://doaj.org/article/0ac755ce9ecd40d88fb16a385464e310
Autor:
Katherine Petrie, Mark Deady, Deborah Lupton, Joanna Crawford, Katherine M. Boydell, Samuel B. Harvey
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Medical practitioners can experience considerable stress and poor mental health during their careers, with doctors in training known to be particularly vulnerable. Previous research has documented work-related factors that may pla
Externí odkaz:
https://doaj.org/article/e0fee0552aeb4afebc8ef35850056973
Publikováno v:
Australian and New Zealand Journal of Public Health, Vol 45, Iss 4, Pp 318-324 (2021)
Abstract Objectives: To examine the perceptions of health professionals regarding the gaps in mental health service provision in Australia and their need for assistance in managing patients with mental illness. Method: A total of 570 health professio
Externí odkaz:
https://doaj.org/article/b76538adf88a46f0a981caa2f8577a80
Autor:
Sushma Marla, Sally Mortlock, Sohye Yoon, Joanna Crawford, Stacey Andersen, Michael D. Mueller, Brett McKinnon, Quan Nguyen, Grant W. Montgomery
Publikováno v:
Cells, Vol 12, Iss 13, p 1736 (2023)
Identifying tissue-specific molecular signatures of active regulatory elements is critical to understanding gene regulatory mechanisms. In this study, transcription start sites (TSS) and enhancers were identified using Cap analysis of gene expression
Externí odkaz:
https://doaj.org/article/3487a2c21f20448eb09f5232b7137e46
Autor:
Arti M. Raghubar, Duy T. Pham, Xiao Tan, Laura F. Grice, Joanna Crawford, Pui Yeng Lam, Stacey B. Andersen, Sohye Yoon, Siok Min Teoh, Nicholas A. Matigian, Anne Stewart, Leo Francis, Monica S. Y. Ng, Helen G. Healy, Alexander N. Combes, Andrew J. Kassianos, Quan Nguyen, Andrew J. Mallett
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Available transcriptomes of the mammalian kidney provide limited information on the spatial interplay between different functional nephron structures due to the required dissociation of tissue with traditional transcriptome-based methodologies. A dee
Externí odkaz:
https://doaj.org/article/f9f48ceb22244753811383cd23084a84
Autor:
Guy Helman, Bryan R. Lajoie, Joanna Crawford, Asako Takanohashi, Marzena Walkiewicz, Egor Dolzhenko, Andrew M. Gross, Vladimir G. Gainullin, Stephen J. Bent, Emma M. Jenkinson, Sacha Ferdinandusse, Hans R. Waterham, Imen Dorboz, Enrico Bertini, Noriko Miyake, Nicole I. Wolf, Truus E. M. Abbink, Susan M. Kirwin, Christina M. Tan, Grace M. Hobson, Long Guo, Shiro Ikegawa, Amy Pizzino, Johanna L. Schmidt, Genevieve Bernard, Raphael Schiffmann, Marjo S. van derKnaap, Cas Simons, Ryan J. Taft, Adeline Vanderver
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 1, Pp 144-152 (2020)
Abstract Genetic white matter disorders have heterogeneous etiologies and overlapping clinical presentations. We performed a study of the diagnostic efficacy of genome sequencing in 41 unsolved cases with prior exome sequencing, resolving an addition
Externí odkaz:
https://doaj.org/article/b313ae0552894ab4b545c7fc6b8eee71
Autor:
Jun Xu, Caitlin Falconer, Quan Nguyen, Joanna Crawford, Brett D. McKinnon, Sally Mortlock, Anne Senabouth, Stacey Andersen, Han Sheng Chiu, Longda Jiang, Nathan J. Palpant, Jian Yang, Michael D. Mueller, Alex W. Hewitt, Alice Pébay, Grant W. Montgomery, Joseph E. Powell, Lachlan J.M Coin
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract A variety of methods have been developed to demultiplex pooled samples in a single cell RNA sequencing (scRNA-seq) experiment which either require hashtag barcodes or sample genotypes prior to pooling. We introduce scSplit which utilizes gen
Externí odkaz:
https://doaj.org/article/1b71a24d668b46c094a1546909858b98
Autor:
Isabelle Counson, Alexandra Bartholomew, Joanna Crawford, Katherine Petrie, Geetanjali Basarkod, Victoria Moynihan, Josie Pires, Rachel Cohen, Nicholas Glozier, Samuel Harvey, Samineh Sanatkar
Publikováno v:
JMIR Formative Research, Vol 5, Iss 12, p e26370 (2021)
BackgroundJunior physicians report higher levels of psychological distress than senior doctors and report several barriers to seeking professional mental health support, including concerns about confidentiality and career progression. Mobile health (
Externí odkaz:
https://doaj.org/article/a1809c61f9bf4c7eb971fc4d6fa25f51