Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Joanna C Grant"'
Autor:
Qingping Xu, Marc C Deller, Tine K Nielsen, Joanna C Grant, Scott A Lesley, Marc-André Elsliger, Ashley M Deacon, Ian A Wilson
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107309 (2014)
Kanadaptin is a nuclear protein of unknown function that is widely expressed in mammalian tissues. The crystal structure of the forkhead-associated (FHA) domain of human kanadaptin was determined to 1.6 Å resolution. The structure reveals an asymmet
Externí odkaz:
https://doaj.org/article/927ce7732ffc4266a9e4e2067c26f1d5
Autor:
Qingping Xu, Neil D Rawlings, Carol L Farr, Hsiu-Ju Chiu, Joanna C Grant, Lukasz Jaroszewski, Heath E Klock, Mark W Knuth, Mitchell D Miller, Dana Weekes, Marc-André Elsliger, Ashley M Deacon, Adam Godzik, Scott A Lesley, Ian A Wilson
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21875 (2011)
Imelysin-like proteins define a superfamily of bacterial proteins that are likely involved in iron uptake. Members of this superfamily were previously thought to be peptidases and were included in the MEROPS family M75. We determined the first crysta
Externí odkaz:
https://doaj.org/article/97645952e15f40f58e65882fee83ec22
Autor:
Aaron A. Thompson, Michael B. Harbut, Pei-Pei Kung, Nathan K. Karpowich, Jeffrey D. Branson, Joanna C. Grant, Deborah Hagan, Heather A. Pascual, Guoyun Bai, Reza Beheshti Zavareh, Heather R. Coate, Bernard C. Collins, Marjorie Côte, Christine F. Gelin, Kelly L. Damm-Ganamet, Hadi Gholami, Adam R. Huff, Luis Limon, Kevin J. Lumb, Puiying A. Mak, Kohki M. Nakafuku, Edmund V. Price, Amy Y. Shih, Mandana Tootoonchi, Nadeem A. Vellore, Jocelyn Wang, Na Wei, Jeannie Ziff, Scott B. Berger, James P. Edwards, Agnès Gardet, Siquan Sun, Jennifer E. Towne, Jennifer D. Venable, Zhicai Shi, Hariharan Venkatesan, Marie-Laure Rives, Sujata Sharma, Brock T. Shireman, Samantha J. Allen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
NKG2D (natural-killer group 2, member D) is a homodimeric transmembrane receptor that plays an important role in NK, γδ + , and CD8 + T cell-mediated immune responses to environmental stressors such as viral or bacterial infections and oxidative st
Autor:
Axel T. Brunger, Paul D. Adams, Thomas C. Terwilliger, Debanu Das, Ashley M. Deacon, Gunnar F. Schröder, Michael Levitt, Randy J. Read, Joanna C Grant
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
DEN refinement and automated model building with AutoBuild were used to determine the structure of a putative succinyl-diaminopimelate desuccinylase from C. glutamicum. This difficult case of molecular-replacement phasing shows that the synergism bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cfc6e252e3f177918ef3efc5765234
Autor:
Joanna C Grant, Qingping Xu, Adam Godzik, Hsiu-Ju Chiu, Ian A. Wilson, Mark W. Knuth, Marc-André Elsliger, Lukasz Jaroszewski, Scott A. Lesley, Matthew Biancalana, Ashley M. Deacon
Publikováno v:
Protein Sci
Free‐standing single‐layer β‐sheets are extremely rare in naturally occurring proteins, even though β‐sheet motifs are ubiquitous. Here we report the crystal structures of three homologous, single‐layer, anti‐parallel β‐sheet protein
Autor:
Marc-André Elsliger, Ian A. Wilson, Joanna C Grant, Mark W. Knuth, Hsiu-Ju Chiu, Ashley M. Deacon, Lukasz Jaroszewski, Mitchell D. Miller, Adam Godzik, Carol L. Farr, Scott A. Lesley
Publikováno v:
Acta crystallographica. Section D, Biological crystallography, vol 70, iss Pt 10
The crystal structure of arabinose-5-phosphate isomerase (API) fromBacteroides fragilis(bfAPI) was determined at 1.7 Å resolution and was found to be a tetramer of a single-domain sugar isomerase (SIS) with an endogenous ligand, CMP-Kdo (cytidine 5
Autor:
Abhinav Kumar, Hsiu-Ju Chiu, Ian A. Wilson, Adam Godzik, Marc-André Elsliger, Debanu Das, Joanna C Grant, Penelope Coggill, Marco Punta, Heath E. Klock, Mitchell D. Miller, Carol L. Farr, Ashley M. Deacon, Scott A. Lesley, Herbert L. Axelrod
Publikováno v:
Protein Science. 23:1380-1391
Crystal structures of three members (BACOVA_00364 from Bacteroides ovatus, BACUNI_03039 from Bacteroides uniformis and BACEGG_00036 from Bacteroides eggerthii) of the Pfam domain of unknown function (DUF4488) were determined to 1.95, 1.66, and 1.81 A
Autor:
Mireille Hervé, Rameshwar U. Kadam, Joanna C Grant, Ashley M. Deacon, M.A. Elsliger, Heath E. Klock, Hsiu-Ju Chiu, Adam Godzik, Debanu Das, Ian A. Wilson, Scott A. Lesley, Mitchell D. Miller, Dominique Mengin-Lecreulx, Mark W. Knuth
Publikováno v:
Journal of bacteriology, vol 195, iss 24
Approximately 50% of cell wall peptidoglycan in Gram-negative bacteria is recycled with each generation. The primary substrates used for peptidoglycan biosynthesis and recycling in the cytoplasm are GlcNAc-MurNAc(anhydro)-tetrapeptide and its degrada
Autor:
Debanu Das, Mark W. Knuth, Scott A. Lesley, Hsiu-Ju Chiu, Adam Godzik, Henry J Tien, Marc-André Elsliger, Joanna C Grant, Ian A. Wilson, Lukasz Jaroszewski, Ashley M. Deacon, Mitchell D. Miller, Carol L. Farr
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:1086-1092
Pseudomonas aeruginosa is an opportunistic pathogen commonly found in humans and other organisms and is an important cause of infection especially in patients with compromised immune defense mechanisms. The PA3611 gene of P. aeruginosa PAO1 encodes a
Autor:
Ashley M. Deacon, Mitchell D. Miller, Mark W. Knuth, Hsiu-Ju Chiu, Qingping Xu, Marc-André Elsliger, Ian A. Wilson, Joanna C Grant, Carol L. Farr, Scott A. Lesley, Lukasz Jaroszewski, Adam Godzik
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:164-170
PF10014 is a novel family of 2-oxyglutarate-Fe(2+) -dependent dioxygenases that are involved in biosynthesis of antibiotics and regulation of biofilm formation, likely by catalyzing hydroxylation of free amino acids or other related ligands. The crys