Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joanna Buchthal"'
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 8, Pp 1592-1593 (2019)
Subtropical lone star tick larvae typically emerge in late summer. We found clusters of host-seeking lone star tick larvae during early June 2018 in New York and Massachusetts, USA. Invasion and persistence of this tick in more northern locations may
Externí odkaz:
https://doaj.org/article/f50a8a69917b400a8c2e7e9a984cecea
Autor:
Xiaoge Guo, Alejandro Chavez, Alissa Lance-Byrne, Angela Tung, Ryan J Cecchi, Nghi Dang, Joanna Buchthal, Nan Cher Yeo
Publikováno v:
Synthetic Biology.
CRISPR/Cas9 has revolutionized the field of genome engineering. Yet, as the CRISPR toolbox has rapidly expanded, there remains a need for a comprehensive library of CRISPR/Cas9 reagents that allow users to perform complex cellular and genetic manipul
Autor:
George M. Church, Andrea L. Smidler, Charleston Noble, Joanna Buchthal, Kevin M. Esvelt, Martin A. Nowak, Alejandro Chavez, Jason Olejarz, Erika A. DeBenedictis, John Min
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance CRISPR-based gene drive systems—genetic elements which could be engineered to rapidly spread traits through wild populations—could help solve some of humanity’s greatest ecological and public health problems. However, if released,
Publikováno v:
Appl Environ Microbiol
Deer tick-transmitted Borrelia burgdorferi sensu stricto (Lyme disease) and Babesia microti (babesiosis) increasingly burden public health across eastern North America. The white-footed mouse is considered the primary host for subadult deer ticks and
Autor:
Benjamin E. Housden, Alejandro Chavez, Ben Ewen-Campen, Emma J. K. Kowal, Dmitry Ter-Ovanesyan, Norbert Perrimon, George M. Church, James J. Collins, Ryan J Cecchi, Benjamin W. Pruitt, Sabina J Haque, Joanna Buchthal, Raj Chari, Marcelle Tuttle
Publikováno v:
Nature Methods. 13:563-567
Several programmable transcription factors exist based on the versatile Cas9 protein, yet their relative potency and effectiveness across various cell types and species remain unexplored. Here, we compare Cas9 activator systems and examine their abil
Autor:
George M. Church, Richard N. Hall, Benjamin W. Pruitt, Suhani Vora, Mohammad R. Ebrahimkhani, Dmitry Ter-Ovanesyan, Jacob Beal, Alejandro Chavez, Samira Kiani, Ron Weiss, Emma J. K. Kowal, James J. Collins, Marcelle Tuttle, Joanna Buchthal, Jason Qian, Raj Chari
Publikováno v:
PMC
We demonstrate that by altering the length of Cas9-associated guide RNA(gRNA) we were able to control Cas9 nuclease activity and simultaneously perform genome editing and transcriptional regulation with a single Cas9 protein. We exploited these princ
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 374(1772):20180105. ROYAL SOC
Philosophical Transactions of the Royal Society B: Biological Sciences
Philosophical Transactions of the Royal Society B: Biological Sciences
Mice Against Ticks is a community-guided ecological engineering project that aims to prevent tick-borne disease by using CRISPR-based genome editing to heritably immunize the white-footed mice ( Peromyscus leucopus ) responsible for infecting many ti