Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Joanna Bereta"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 711-731 (2021)
In parallel with the expansion of RNA interference (RNAi) techniques, accumulating evidence indicates that RNAi analyses might be seriously biased due to the off-target effects of gene-specific short hairpin RNAs (shRNAs). Our findings indicated that
Externí odkaz:
https://doaj.org/article/ba660ea76d094a3381dfa9b500a05a08
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The binding of mouse IgG3 to Fcγ receptors (FcγR) and the existence of a mouse IgG3-specific receptor have been discussed for 40 years. Recently, integrin beta-1 (ITGB1) was proposed to be a part of an IgG3 receptor involved in the phagocy
Externí odkaz:
https://doaj.org/article/2bbaaea2d9a7418096ecc6dd6f69a07b
Publikováno v:
Biology Open, Vol 11, Iss 3 (2022)
RNA interference is one of the common methods of studying protein functions. In recent years critical reports have emerged indicating that off-target effects may have a much greater impact on RNAi-based analysis than previously assumed. We studied th
Externí odkaz:
https://doaj.org/article/42563579b5294978bcf8cacdb4c9bbbf
Publikováno v:
Biology Open, Vol 8, Iss 2 (2019)
ADAM17 is a cell membrane metalloproteinase responsible for the release of ectodomains of numerous proteins from the cell surface. Although ADAM17 is often overexpressed in tumours and at sites of inflammation, little is known about the regulation of
Externí odkaz:
https://doaj.org/article/ddee771f9c8d4b4587f0eb4f5f7168e2
Autor:
Tomasz Klaus, Joanna Bereta
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mouse IgG3 is highly protective against several life-threatening bacteria. This isotype is the only one among mouse IgGs that forms non-covalent oligomers, has increased functional affinity to polyvalent antigens, and efficiently agglutinates erythro
Externí odkaz:
https://doaj.org/article/c74f37eb868a4526b6a926b7b17d288c
Autor:
Bartlomiej Kalaska, Kamil Kaminski, Emilia Sokolowska, Dominik Czaplicki, Monika Kujdowicz, Krystyna Stalinska, Joanna Bereta, Krzysztof Szczubialka, Dariusz Pawlak, Maria Nowakowska, Andrzej Mogielnicki
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119486 (2015)
Protamine, the only registered antidote of unfractionated heparin (UFH), may produce a number of adverse effects, such as anaphylactic shock or serious hypotension. We aimed to develop an alternative UFH antidote as efficient as protamine, but safer
Externí odkaz:
https://doaj.org/article/5ddbab7f7d014d5cb8e4535beec460b0
Autor:
Renata Mężyk-Kopeć, Barbara Wyroba, Krystyna Stalińska, Tomasz Próchnicki, Karolina Wiatrowska, Witold W Kilarski, Melody A Swartz, Joanna Bereta
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132661 (2015)
Tumor-associated lymphatic vessels actively participate in tumor progression and dissemination. ADAM17, a sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules, is believed to promote tumor development, facilitating
Externí odkaz:
https://doaj.org/article/ca5c9b3bc81c43888bc051bdfae04a8d
Autor:
Sudipta Das, Maria Czarnek, Monika Bzowska, Renata Mężyk-Kopeć, Krystyna Stalińska, Barbara Wyroba, Jolanta Sroka, Jarosław Jucha, Dawid Deneka, Paulina Stokłosa, Justyna Ogonek, Melody A Swartz, Zbigniew Madeja, Joanna Bereta
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50791 (2012)
ADAM17 (a disintegrin and metalloprotease 17) is a major sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules and is often overexpressed in malignant cells. It is generally accepted that ADAM17 promotes tumor develo
Externí odkaz:
https://doaj.org/article/8656bee2c12d4a449e7fa9ea5ac56467
Publikováno v:
Molecular Biotechnology.
In recent years, CRISPR interference (CRISPRi) technology of gene silencing has emerged as a promising alternative to RNA interference (RNAi) surpassing the latter in terms of efficiency and accuracy. Here, we describe the construction of a set of tr
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 26, Iss, Pp 711-731 (2021)
Molecular Therapy: Nucleic Acids, Vol 26, Iss, Pp 711-731 (2021)
In parallel with the expansion of RNA interference (RNAi) techniques, accumulating evidence indicates that RNAi analyses might be seriously biased due to the off-target effects of gene-specific short hairpin RNAs (shRNAs). Our findings indicated that